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DK0637236T3 - Pharmaceutical composition and process for its preparation - Google Patents

Pharmaceutical composition and process for its preparation

Info

Publication number
DK0637236T3
DK0637236T3 DK93908973.6T DK93908973T DK0637236T3 DK 0637236 T3 DK0637236 T3 DK 0637236T3 DK 93908973 T DK93908973 T DK 93908973T DK 0637236 T3 DK0637236 T3 DK 0637236T3
Authority
DK
Denmark
Prior art keywords
preparation
pharmaceutical composition
prepn
clodronate
dissolves
Prior art date
Application number
DK93908973.6T
Other languages
Danish (da)
Inventor
Juhani Posti
Kirsi Katila
Pertti Rantala
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Application granted granted Critical
Publication of DK0637236T3 publication Critical patent/DK0637236T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A pharmaceutical prepn. for oral use comprises, as active agent, dichloromethylene bisphosphonic acid (clodronate) (I) or a pharmacologically acceptable salt, the prepn. being enteric coated with a film which dissolves at pH 5-7.2.
DK93908973.6T 1992-04-24 1993-04-21 Pharmaceutical composition and process for its preparation DK0637236T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9201299A SE501389C2 (en) 1992-04-24 1992-04-24 Pharmaceutical preparation and process for its preparation

Publications (1)

Publication Number Publication Date
DK0637236T3 true DK0637236T3 (en) 1997-03-17

Family

ID=20386054

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93908973.6T DK0637236T3 (en) 1992-04-24 1993-04-21 Pharmaceutical composition and process for its preparation

Country Status (21)

Country Link
US (1) US5525354A (en)
EP (1) EP0637236B1 (en)
JP (1) JP3536106B2 (en)
AT (1) ATE143802T1 (en)
AU (1) AU671830B2 (en)
CA (1) CA2134196C (en)
CZ (1) CZ282871B6 (en)
DE (2) DE69305335T2 (en)
DK (1) DK0637236T3 (en)
EE (1) EE03107B1 (en)
ES (1) ES2094539T3 (en)
FI (1) FI110667B (en)
GR (1) GR3022249T3 (en)
HK (1) HK13097A (en)
HU (1) HU219342B (en)
IL (1) IL105403A (en)
NO (1) NO306654B1 (en)
RU (1) RU2116074C1 (en)
SE (1) SE501389C2 (en)
TW (1) TW273515B (en)
WO (1) WO1993021907A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6406714B1 (en) 1992-12-02 2002-06-18 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids
HU220872B1 (en) † 1993-05-15 2002-06-29 Roche Diagnostics Gmbh Tablets containing dichloromethylene diphosphonic acid as active agent with enhanced bioavailability and process for producing them
US5431920A (en) * 1993-09-21 1995-07-11 Merck Frosst, Canada, Inc. Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
FI94926C (en) * 1993-11-12 1995-11-27 Leiras Oy Method for preparing a clodronate preparation
TW390813B (en) * 1994-04-29 2000-05-21 Merck & Co Inc Wet granulation formulation for bisphosphonic acids
US20010007863A1 (en) 1998-06-18 2001-07-12 Merck & Co., Inc. Wet granulation formulation for bisphosphonic acids
FI98343C (en) * 1995-03-21 1997-06-10 Orion Yhtymae Oy Oral formulation
DE19719680A1 (en) 1997-05-09 1998-11-19 Boehringer Mannheim Gmbh Use of diphosphonic acids for the preventive treatment of long-term consequences of bladder enlargement or replacement
JPH11137208A (en) * 1997-11-14 1999-05-25 Nikken Chem Co Ltd Solid material rapidly soluble in oral cavity and its production
EP0998932A1 (en) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Solid pharmaceutical dosage form containing diphosphonates or their salts and method for its production
EP0998933A1 (en) * 1998-10-09 2000-05-10 Boehringer Mannheim Gmbh Process for producing pharmaceutical compositions containing diphosphonates for oral administration
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
ES2301477T3 (en) * 1999-02-22 2008-07-01 Merrion Research I Limited SOLID ORAL DOSAGE FORM CONTAINING A POTENTIATOR.
SE9901272D0 (en) * 1999-04-09 1999-04-09 Astra Ab New improved formulation
PE20011065A1 (en) 2000-02-01 2001-11-21 Procter & Gamble PROCESS FOR MANUFACTURING GEMINAL BISPHOSPHONATES
PE20011061A1 (en) 2000-02-01 2001-11-20 Procter & Gamble SELECTIVE CRYSTALLIZATION OF 3-PYRIDYL-1-HYDROXY-ETHYLIDEN-1,1-BISPHOSPHONIC SODIUM ACID AS HEMIPENTAHYDRATE OR MONOHYDRATE
MXPA03007837A (en) * 2001-03-01 2004-03-16 Emisphere Techonologies Inc Compositions for delivering bisphosphonates.
JP2004537516A (en) 2001-05-11 2004-12-16 オラセンス リミテッド Antisense penetration enhancer
US20030070584A1 (en) * 2001-05-15 2003-04-17 Cynthia Gulian Dip coating compositions containing cellulose ethers
AU4061702A (en) * 2001-05-15 2003-04-03 Mcneil-Ppc, Inc. Dip coating compositions containing starch or dextrin
US8309118B2 (en) * 2001-09-28 2012-11-13 Mcneil-Ppc, Inc. Film forming compositions containing sucralose
US7429619B2 (en) * 2002-08-02 2008-09-30 Mcneil Consumer Healthcare Polyacrylic film forming compositions
US20080287400A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7645459B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of bisphosphonates
US20080286359A1 (en) 2004-05-24 2008-11-20 Richard John Dansereau Low Dosage Forms Of Risedronate Or Its Salts
US7645460B2 (en) 2004-05-24 2010-01-12 The Procter & Gamble Company Dosage forms of risedronate
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
AU2007235251B2 (en) 2006-04-07 2013-02-07 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
KR20110007614A (en) 2008-05-07 2011-01-24 메리온 리서치 Ⅲ 리미티드 Composition and preparation method of RNNH related compounds
DE102008022520A1 (en) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Solid sustained-release pharmaceutical formulation
WO2011120033A1 (en) 2010-03-26 2011-09-29 Merrion Research Iii Limited Pharmaceutical compositions of selective factor xa inhibitors for oral administration
AU2012204213A1 (en) 2011-01-07 2013-06-13 Merrion Research Iii Limited Pharmaceutical compositions of iron for oral administration
ES2975708T3 (en) 2015-01-29 2024-07-12 Novo Nordisk As Tablets comprising GLP-1 agonist and enteric coating

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
ES2040733T3 (en) * 1986-12-20 1993-11-01 Boehringer Mannheim Gmbh MEDICINES CONTAINING CLODRONATE AND PROCEDURE FOR ITS PREPARATION.
EP0313845A1 (en) * 1987-09-29 1989-05-03 Warner-Lambert Company Stabilization of enteric coated dosage form
FR2629716B1 (en) * 1988-04-07 1991-07-19 Sanofi Sa PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION BASED ON A DIPHOSPHONIC ACID DERIVATIVE

Also Published As

Publication number Publication date
EP0637236B1 (en) 1996-10-09
HUT74572A (en) 1997-01-28
SE501389C2 (en) 1995-01-30
NO306654B1 (en) 1999-12-06
NO944001D0 (en) 1994-10-21
AU671830B2 (en) 1996-09-12
DE637236T1 (en) 1995-07-06
ATE143802T1 (en) 1996-10-15
US5525354A (en) 1996-06-11
FI110667B (en) 2003-03-14
HK13097A (en) 1997-02-14
GR3022249T3 (en) 1997-04-30
RU2116074C1 (en) 1998-07-27
TW273515B (en) 1996-04-01
DE69305335T2 (en) 1997-04-30
SE9201299L (en) 1993-10-25
SE9201299D0 (en) 1992-04-24
IL105403A (en) 1998-03-10
EE03107B1 (en) 1998-08-17
CZ261494A3 (en) 1995-02-15
EP0637236A1 (en) 1995-02-08
DE69305335D1 (en) 1996-11-14
NO944001L (en) 1994-10-21
CA2134196C (en) 2004-02-10
ES2094539T3 (en) 1997-01-16
CA2134196A1 (en) 1993-11-11
IL105403A0 (en) 1993-08-18
JPH07505898A (en) 1995-06-29
RU94045950A (en) 1996-11-10
WO1993021907A1 (en) 1993-11-11
AU3955093A (en) 1993-11-29
JP3536106B2 (en) 2004-06-07
CZ282871B6 (en) 1997-11-12
FI944961L (en) 1994-10-21
HU219342B (en) 2001-03-28
FI944961A0 (en) 1994-10-21
HU9403067D0 (en) 1994-12-28

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