DK0571253T3 - Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning - Google Patents
Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkningInfo
- Publication number
- DK0571253T3 DK0571253T3 DK93401239T DK93401239T DK0571253T3 DK 0571253 T3 DK0571253 T3 DK 0571253T3 DK 93401239 T DK93401239 T DK 93401239T DK 93401239 T DK93401239 T DK 93401239T DK 0571253 T3 DK0571253 T3 DK 0571253T3
- Authority
- DK
- Denmark
- Prior art keywords
- antidiabetic
- benzimidazole derivatives
- coagulant effect
- platelet coagulant
- platelet
- Prior art date
Links
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 230000000702 anti-platelet effect Effects 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
- 230000009852 coagulant defect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9206036A FR2691462B1 (fr) | 1992-05-19 | 1992-05-19 | Nouveaux derives du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR9209488A FR2694293B1 (fr) | 1992-07-31 | 1992-07-31 | Nouveau dérivé du benzimidazole, son procédé de préparation et les compositions pharmaceutiques qui le contiennent. |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0571253T3 true DK0571253T3 (da) | 1999-07-19 |
Family
ID=26229468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93401239T DK0571253T3 (da) | 1992-05-19 | 1993-05-14 | Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning |
Country Status (10)
Country | Link |
---|---|
US (2) | US5623073A (da) |
EP (1) | EP0571253B1 (da) |
JP (1) | JP2506263B2 (da) |
AT (1) | ATE172975T1 (da) |
AU (1) | AU656466B2 (da) |
CA (1) | CA2096475A1 (da) |
DE (1) | DE69321875T2 (da) |
DK (1) | DK0571253T3 (da) |
ES (1) | ES2126636T3 (da) |
NZ (1) | NZ247643A (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1159277C (zh) | 1993-06-25 | 2004-07-28 | 默里尔药物公司 | 用于制备抗组胺哌啶衍生物的新中间体 |
US6147216A (en) * | 1993-06-25 | 2000-11-14 | Merrell Pharmaceuticals Inc. | Intermediates useful for the preparation of antihistaminic piperidine derivatives |
AUPN236595A0 (en) | 1995-04-11 | 1995-05-11 | Rescare Limited | Monitoring of apneic arousals |
FR2765223B1 (fr) * | 1997-06-25 | 1999-08-27 | Adir | Nouveaux derives tricycliques du benzimidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6930197B2 (en) | 1998-07-02 | 2005-08-16 | Aventis Pharmaceuticals Inc. | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
US6683094B2 (en) | 1998-07-02 | 2004-01-27 | Aventis Pharmaceuticals Inc. | Antihistaminic piperidine derivatives and intermediates for the preparation thereof |
JP3398121B2 (ja) | 2000-05-16 | 2003-04-21 | 株式会社堀場製作所 | 粒度分布測定装置 |
US6888004B2 (en) * | 2001-01-26 | 2005-05-03 | Bristol-Myers Squibb Company | Imidazolyl derivatives as corticotropin releasing factor inhibitors |
WO2005113004A2 (en) * | 2004-05-14 | 2005-12-01 | The Cleveland Clinic Founfation | Small molecule inhibitors for mrp1 and other multidrug transporters |
CA2646437C (en) * | 2006-03-17 | 2016-05-17 | Ambit Biosciences Corporation | Imidazolothiazole compounds for the treatment of disease |
KR20150104231A (ko) * | 2007-09-19 | 2015-09-14 | 암비트 바이오사이언시즈 코포레이션 | N-(5-tert-부틸-이속사졸-3-일)-N''-[4-[7-(2-모르폴린-4-일-에톡시)이미다조[2,1-B][1,3]벤조티아졸-2-일]페닐]우레아를 포함하는 고체 형태, 그의 조성물 및 그의 용도 |
EP2268620A4 (en) * | 2008-03-27 | 2011-08-10 | Burnham Inst Medical Research | INHIBITORS OF THE ANTIGEN RECEPTOR-INDUCED ACTIVATION OF NF-KAPPA-B |
GB0808968D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substitute quinazolines |
GB0808952D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substituted quinazolines |
GB0808967D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substitute quinazolines |
GB0808947D0 (en) * | 2008-05-16 | 2008-06-25 | Shire Llc | Substituted quinazolines |
IN2014MN00258A (da) * | 2011-07-15 | 2015-09-25 | Janssen Pharmaceuticals Inc | |
HRP20211156T1 (hr) * | 2015-08-28 | 2021-12-24 | Chdi Foundation, Inc. | Kontrastna sredstva za slikovnu dijagnostiku huntingtin proteina |
CN108250202B (zh) * | 2018-01-15 | 2019-10-25 | 陕西师范大学 | 2,3-二取代苯并咪唑并[1,2-a]嘧啶类化合物及其制备方法和应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3732243A (en) * | 1970-06-23 | 1973-05-08 | Sankyo Co | 2-(p-bromophenyl)-9-dimethyl-amino-propyl-9h-imidazo(1,2-a)benzimidazole |
GB1476949A (en) * | 1974-11-20 | 1977-06-16 | Wyeth John & Brother Ltd | Imidazo-1,2-a-benzimidazole and pyrimido-1,2-a-benzimidazole derivatives their preparation and their pharmaceutical compositions |
US5008282A (en) * | 1988-12-28 | 1991-04-16 | Kotobuki Seiyaku Co. Ltd. | Cyclic guanidine derivatives, anti-ulceratives and methods of manufacturing the same |
-
1993
- 1993-05-14 EP EP93401239A patent/EP0571253B1/fr not_active Expired - Lifetime
- 1993-05-14 DE DE69321875T patent/DE69321875T2/de not_active Expired - Fee Related
- 1993-05-14 DK DK93401239T patent/DK0571253T3/da active
- 1993-05-14 ES ES93401239T patent/ES2126636T3/es not_active Expired - Lifetime
- 1993-05-14 AT AT93401239T patent/ATE172975T1/de active
- 1993-05-18 JP JP5151016A patent/JP2506263B2/ja not_active Expired - Lifetime
- 1993-05-18 US US08/063,531 patent/US5623073A/en not_active Expired - Fee Related
- 1993-05-18 CA CA002096475A patent/CA2096475A1/fr not_active Abandoned
- 1993-05-18 AU AU38608/93A patent/AU656466B2/en not_active Ceased
- 1993-05-18 NZ NZ247643A patent/NZ247643A/en unknown
-
1994
- 1994-10-28 US US08/330,903 patent/US5639756A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2096475A1 (fr) | 1993-11-20 |
ATE172975T1 (de) | 1998-11-15 |
US5639756A (en) | 1997-06-17 |
ES2126636T3 (es) | 1999-04-01 |
EP0571253B1 (fr) | 1998-11-04 |
DE69321875D1 (de) | 1998-12-10 |
AU3860893A (en) | 1993-11-25 |
EP0571253A1 (fr) | 1993-11-24 |
JP2506263B2 (ja) | 1996-06-12 |
JPH0687859A (ja) | 1994-03-29 |
NZ247643A (en) | 1995-07-26 |
US5623073A (en) | 1997-04-22 |
DE69321875T2 (de) | 1999-06-17 |
AU656466B2 (en) | 1995-02-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0571253T3 (da) | Benzimidazolderivater med antidiabetisk og antiblodpladekoagulerende virkning | |
IS4185A (is) | Hliðstæð aðferð til framleiðslu fenýlsúlfonylamino-pýrimidines afleiða | |
ATE18902T1 (de) | Aminosaeurederivate und ihre therapeutischen verwendungen. | |
FI914928A0 (fi) | Hydroximetyl (metylencyklopentyl) puriner och -pyrimidiner. | |
TR199501253A2 (tr) | Amino(tio) eter türevleri. | |
NO179834C (no) | Substituerte cykloheksanderivater og anvendelse av forbindelsene for fremstilling av legemidler | |
FI932105A0 (fi) | Sulfonylbensylsubstituerade benso- och pyridopyridoner | |
NZ240575A (en) | N-benzoylproline derivatives and pharmaceutical compositions | |
DK0459256T3 (da) | Oxazolidiononer | |
DE69115526D1 (de) | 2,4-Pyrimidindionderivate und diese enthaltende Arzneimittel | |
IT1270975B (it) | Composti piperidin-triazinici atti all'impiego come stabilizzanti allaluce, al calore e alla ossidazione per materiali organici | |
NO306116B1 (no) | Ny benzotiadiazinforbindelse og farmasöytiske sammensetninger | |
FI892675A0 (fi) | 2,6-dihalogenpyridin-3 -karboxylsyraderivat och deras framstaellning. | |
DE59404557D1 (de) | Hetero-tricyclisch-substituierte Phenyl-cyclohexan-carbonsäurederivate | |
ATE170862T1 (de) | 5-ht3 pyrrolopyrazinderivate | |
DK0625520T3 (da) | Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet | |
IT1263892B (it) | Composti piperidin-triazinici atti all'impiego come stabilizzanti per materiali organici | |
ATE123025T1 (de) | 2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica. | |
DK0552631T3 (da) | Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider | |
ATE111099T1 (de) | Ergolinderivate. | |
ES2061182T3 (es) | 2-fluoroneplanocina a y su fabricacion. |