DK0565558T3 - Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer - Google Patents

Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer

Info

Publication number: DK0565558T3
Authority: DK; Denmark
Prior art keywords: octan; azabicyclo; imines; intermediates; preparation
Prior art date: 1991-01-03

Application number

DK92901603.8T

Other languages

English (en)

Inventor

Dennis M Godek

Charles W Murtiashaw

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-01-03

Filing date

1991-12-18

Publication date

1995-03-06

1991-12-18 Application filed by Pfizer filed Critical Pfizer

1995-03-06 Application granted granted Critical

1995-03-06 Publication of DK0565558T3 publication Critical patent/DK0565558T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Indole Compounds (AREA)
Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)

DK92901603.8T 1991-01-03 1991-12-18 Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer DK0565558T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/637,102 US5138060A (en)	1991-01-03	1991-01-03	Process and intermediates for preparing azabicyclo(2.2.2)octan-3-imines

Publications (1)

Publication Number	Publication Date
DK0565558T3 true DK0565558T3 (da)	1995-03-06

Family

ID=24554545

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92901603.8T DK0565558T3 (da)	1991-01-03	1991-12-18	Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer

Country Status (21)

Country	Link
US (1)	US5138060A (da)
EP (1)	EP0565558B1 (da)
JP (5)	JPH05508867A (da)
KR (1)	KR970001157B1 (da)
AT (1)	ATE115580T1 (da)
AU (1)	AU653380B2 (da)
CA (2)	CA2098989C (da)
DE (1)	DE69106003T2 (da)
DK (1)	DK0565558T3 (da)
ES (1)	ES2065161T3 (da)
FI (3)	FI933065A0 (da)
GR (1)	GR3015021T3 (da)
HU (1)	HU9301931D0 (da)
IE (1)	IE65005B1 (da)
IL (1)	IL100541A0 (da)
MX (1)	MX9200003A (da)
NO (1)	NO932431L (da)
NZ (1)	NZ241161A (da)
PT (1)	PT99970B (da)
WO (1)	WO1992012152A1 (da)
ZA (1)	ZA928B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5364943A (en) *	1991-11-27	1994-11-15	Pfizer Inc.	Preparation of substituted piperidines
PL170516B1 (en) *	1991-06-20	1996-12-31	Pfizer	Method of obtaining novel derivatives of fluoroalkoxy benzylaminic compounds of piperidine
CA2123403C (en) *	1991-11-12	2002-02-05	Brian T. O'neill	Acyclic ethylenediamine derivatives as substance p receptor antagonists
DE69331190T2 (de) *	1992-05-18	2002-04-18	Pfizer Inc., New York	Überbrückte azabicyclische derivate als substanz p antagonisten
US5637699A (en) *	1992-06-29	1997-06-10	Merck & Co., Inc.	Process for preparing morpholine tachykinin receptor antagonists
US5719147A (en) *	1992-06-29	1998-02-17	Merck & Co., Inc.	Morpholine and thiomorpholine tachykinin receptor antagonists
US6048859A (en)	1992-06-29	2000-04-11	Merck & Co., Inc.	Morpholine and thiomorpholine tachykinin receptor antagonists
JPH07506379A (ja) *	1992-08-04	1995-07-13	ファイザー・インコーポレーテッド	物質ｐ受容体アンタゴニストとしての３−ベンジルアミノ−２−フェニル−ピペリジン
US5387595A (en) *	1992-08-26	1995-02-07	Merck & Co., Inc.	Alicyclic compounds as tachykinin receptor antagonists
US5518628A (en) *	1993-11-08	1996-05-21	Shipley Company Inc.	Purification process
TW385308B (en) *	1994-03-04	2000-03-21	Merck & Co Inc	Prodrugs of morpholine tachykinin receptor antagonists
US6861526B2 (en)	2002-10-16	2005-03-01	Pfizer Inc.	Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
US20050112695A1 (en) *	2003-10-27	2005-05-26	Meyer Donald W.	Method of detecting bovine spongiform encephalopathy

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3560510A (en) *	1969-03-05	1971-02-02	Aldrich Chem Co Inc	2-benzhydrylquinuclidines
US3993652A (en) *	1973-07-09	1976-11-23	Air Products And Chemicals, Inc.	Cyclic quaternary hydroxyalkyl phenoxide catalysts for isocyanate reactions
US4203990A (en) *	1979-04-30	1980-05-20	G. D. Searle & Co.	Anti-diarrheal 2-substituted quinuclidines
FR2529548A1 (fr) *	1982-07-02	1984-01-06	Delalande Sa	Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS59110656A (ja) *	1982-12-15	1984-06-26	Hiroyuki Nohira	光学活性な１―フェニル―２―（パラ―トリル）エチルアミンの製造方法
DE3604591A1 (de) *	1986-02-14	1987-08-20	Degussa	Verfahren zur herstellung chiraler glycinderivate
JPS6354342A (ja) *	1986-08-26	1988-03-08	Daicel Chem Ind Ltd	（±）−α−エチルベンジルアミンの光学分割方法
JPS63145256A (ja) *	1986-12-09	1988-06-17	Nippon Kayaku Co Ltd	光学活性ホモフエニルアラニンの製造法及び中間体
MX18467A (es) *	1988-11-23	1993-07-01	Pfizer	Agentes terapeuticos de quinuclidinas
CA2109415C (en) *	1991-05-22	1998-12-29	Fumitaka Ito	Substituted 3-aminoquinuclidines

1991
- 1991-01-03 US US07/637,102 patent/US5138060A/en not_active Expired - Lifetime
- 1991-12-18 WO PCT/US1991/009186 patent/WO1992012152A1/en active Application Filing
- 1991-12-18 DK DK92901603.8T patent/DK0565558T3/da active
- 1991-12-18 CA CA002098989A patent/CA2098989C/en not_active Expired - Fee Related
- 1991-12-18 JP JP92502391A patent/JPH05508867A/ja not_active Withdrawn
- 1991-12-18 ES ES92901603T patent/ES2065161T3/es not_active Expired - Lifetime
- 1991-12-18 FI FI933065A patent/FI933065A0/fi not_active Application Discontinuation
- 1991-12-18 EP EP92901603A patent/EP0565558B1/en not_active Expired - Lifetime
- 1991-12-18 HU HU9301931A patent/HU9301931D0/hu unknown
- 1991-12-18 AU AU91298/91A patent/AU653380B2/en not_active Expired - Fee Related
- 1991-12-18 AT AT92901603T patent/ATE115580T1/de not_active IP Right Cessation
- 1991-12-18 JP JP4502391A patent/JPH0768244B1/ja active Pending
- 1991-12-18 CA CA002158130A patent/CA2158130C/en not_active Expired - Fee Related
- 1991-12-18 DE DE69106003T patent/DE69106003T2/de not_active Expired - Fee Related
- 1991-12-18 KR KR1019930702007A patent/KR970001157B1/ko not_active Expired - Lifetime
- 1991-12-23 NZ NZ241161A patent/NZ241161A/en unknown
- 1991-12-27 IL IL100541A patent/IL100541A0/xx unknown
1992
- 1992-01-02 PT PT99970A patent/PT99970B/pt not_active IP Right Cessation
- 1992-01-02 MX MX9200003A patent/MX9200003A/es unknown
- 1992-01-02 IE IE920001A patent/IE65005B1/en not_active IP Right Cessation
- 1992-01-02 ZA ZA928A patent/ZA928B/xx unknown
1993
- 1993-07-02 NO NO93932431A patent/NO932431L/no unknown
1994
- 1994-12-26 JP JP6322350A patent/JP2845425B2/ja not_active Expired - Fee Related
- 1994-12-26 JP JP6322355A patent/JP2703193B2/ja not_active Expired - Fee Related
- 1994-12-26 JP JP6322353A patent/JP2583026B2/ja not_active Expired - Fee Related
1995
- 1995-02-08 GR GR950400264T patent/GR3015021T3/el unknown
2000
- 2000-05-10 FI FI20001108A patent/FI20001108L/fi not_active Application Discontinuation
- 2000-05-10 FI FI20001109A patent/FI20001109A7/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO932431D0 (no)	1993-07-02
FI933065A7 (fi)	1993-07-02
FI20001109L (fi)	2000-05-10
JPH05508867A (ja)	1993-12-09
EP0565558B1 (en)	1994-12-14
US5138060A (en)	1992-08-11
FI20001109A7 (fi)	2000-05-10
CA2098989C (en)	1998-02-03
CA2098989A1 (en)	1992-07-04
FI20001108A7 (fi)	2000-05-10
IL100541A0 (en)	1992-09-06
JPH07316154A (ja)	1995-12-05
JPH07316153A (ja)	1995-12-05
WO1992012152A1 (en)	1992-07-23
CA2158130C (en)	1998-07-14
JPH07330766A (ja)	1995-12-19
MX9200003A (es)	1992-07-01
CA2158130A1 (en)	1992-07-04
FI933065L (fi)	1993-07-02
EP0565558A1 (en)	1993-10-20
ATE115580T1 (de)	1994-12-15
DE69106003T2 (de)	1995-04-27
DE69106003D1 (de)	1995-01-26
ES2065161T3 (es)	1995-02-01
JP2703193B2 (ja)	1998-01-26
IE65005B1 (en)	1995-10-04
GR3015021T3 (en)	1995-05-31
JPH0768244B1 (da)	1995-07-26
JP2583026B2 (ja)	1997-02-19
NZ241161A (en)	1994-10-26
JP2845425B2 (ja)	1999-01-13
PT99970A (pt)	1993-02-26
ZA928B (en)	1993-07-02
HU9301931D0 (en)	1993-12-28
IE920001A1 (en)	1992-07-15
AU9129891A (en)	1992-08-17
FI20001108L (fi)	2000-05-10
KR970001157B1 (ko)	1997-01-29
PT99970B (pt)	1999-06-30
NO932431L (no)	1993-07-02
AU653380B2 (en)	1994-09-29
FI933065A0 (fi)	1993-07-02
KR930703312A (ko)	1993-11-29

Publication	Publication Date	Title
AU518470B2 (en)	1981-10-01	2-(2-alkoxyethyl)-2:-hydroxy-6,7-benzomorphanes
DK0565558T3 (da)	1995-03-06	Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer
NO823836L (no)	1983-05-18	Fremgangsmaate ved fremstilling av antifibrinolytisk aktive forbindelser.
DK0532515T3 (da)	1997-04-21	Fremstilling af substituerede piperidiner
CA2065008A1 (en)	1991-03-01	Light Activated Acyl-Enzymes
DK0619806T3 (da)	1996-02-05	Fremstilling af substituerede piperidiner
ZA9419B (en)	1995-01-04	Preparation process for sulphurated derivatives of imidazole and the new intermediates obtained.
DK305879A (da)	1980-01-22	R fremgangsmaade til fremstilling af oxadiazolpyrimidinderivate
EP0598910A4 (en)	1994-02-07	METHOD FOR PRODUCING NUCLEOSIDE DERIVATIVES.
DK0779895T3 (da)	2000-03-13	Forbedret fremgangsmåde til fremstilling af sidekædederivater af cyclohexapeptidyl-lipopeptider
SE8002827L (sv)	1980-10-17	Antibiotikum och sett for dess framstellning
DK0662475T3 (da)	1998-06-02	Fremgangsmåde til fremstilling af 2-perfluoralkyl-3-oxazolin-5-on.
DK0661263T3 (da)	2001-07-02	Fremgangsmåde til fremstilling af 2,4,5-tribrompyrrol-3-carbonitril
GB2226315B (en)	1991-02-06	Intermediates useful in the production of pesticides
IT1270834B (it)	1997-05-13	Disolfuro chinolico
SE7905060L (sv)	1979-12-13	Nya 1-pyrrol- och 1-pyrrolidin-karboxylsyraderivat och sett for framstellning derav
DK0678515T3 (da)	1998-11-02	Fremgangsmåde og mellemprodukter til fremstilling af 5-oxaspiro[2.4]heptan-on
DK0614890T3 (da)	1997-10-13	Fremgangsmåde til fremstilling af eventuelt 2-substituerede 5-chlorimidazoler.
ES2164258T3 (es)	2002-02-16	Procedimiento de preparacion de derivados de carbamoilmetilurea.
DK452684D0 (da)	1984-09-21	Fremgangsmaade til fremstilling af quinolin-4-oner
DK0555283T3 (da)	1995-07-03	Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre