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DK0559884T4 - Recombinant viral vectors for expression in muscle cells - Google Patents

Recombinant viral vectors for expression in muscle cells

Info

Publication number
DK0559884T4
DK0559884T4 DK92921684T DK92921684T DK0559884T4 DK 0559884 T4 DK0559884 T4 DK 0559884T4 DK 92921684 T DK92921684 T DK 92921684T DK 92921684 T DK92921684 T DK 92921684T DK 0559884 T4 DK0559884 T4 DK 0559884T4
Authority
DK
Denmark
Prior art keywords
muscle cells
expression
vectors
viral vectors
recombinant viral
Prior art date
Application number
DK92921684T
Other languages
Danish (da)
Other versions
DK0559884T3 (en
Inventor
Michel Perricaudet
Pascale Briand
Leslie Stratford-Perricaudet
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9417378&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0559884(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK0559884T3 publication Critical patent/DK0559884T3/en
Publication of DK0559884T4 publication Critical patent/DK0559884T4/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Non-replicatable viral recombinant vectors which are recognizable by muscle cell receptors, and furthermore modified by an insertion nucleic acid coding for a polypeptide sequence to be expressed in said muscle cells, are used to obtain a drug for treating muscle cell diseases or diseases which, by virtue of their location in the body, are accessible to the products of the expression of the above mentioned nucleotide sequence, as secreted by said muscle cells. A method for producing said vectors, vectors such as those described above, and their use in pharmaceutical compositions are also provided.
DK92921684T 1991-09-27 1992-09-25 Recombinant viral vectors for expression in muscle cells DK0559884T4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9111947A FR2681786A1 (en) 1991-09-27 1991-09-27 RECOMBINANT VECTORS OF VIRAL ORIGIN, PROCESS FOR OBTAINING SAME AND THEIR USE FOR THE EXPRESSION OF POLYPEPTIDES IN MUSCLE CELLS.
PCT/FR1992/000898 WO1993006223A1 (en) 1991-09-27 1992-09-25 Viral recombinant vectors for expression in muscle cells

Publications (2)

Publication Number Publication Date
DK0559884T3 DK0559884T3 (en) 2000-10-02
DK0559884T4 true DK0559884T4 (en) 2004-08-02

Family

ID=9417378

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92921684T DK0559884T4 (en) 1991-09-27 1992-09-25 Recombinant viral vectors for expression in muscle cells

Country Status (12)

Country Link
EP (1) EP0559884B2 (en)
JP (1) JP3487597B2 (en)
AT (1) ATE192500T1 (en)
AU (1) AU666142B2 (en)
CA (1) CA2097185C (en)
DE (1) DE69230993T3 (en)
DK (1) DK0559884T4 (en)
ES (1) ES2147553T5 (en)
FR (1) FR2681786A1 (en)
GR (1) GR3034094T3 (en)
SG (1) SG49081A1 (en)
WO (1) WO1993006223A1 (en)

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ATE304604T1 (en) * 1993-06-24 2005-09-15 Frank L Graham ADENOVIRUS VECTORS FOR GENE THERAPY
US6730507B1 (en) 1993-06-24 2004-05-04 Merck & Co., Inc. Use of helper-dependent adenoviral vectors of alternative serotypes permits repeat vector administration
US6080569A (en) * 1993-06-24 2000-06-27 Merck & Co., Inc. Adenovirus vectors generated from helper viruses and helper-dependent vectors
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US6281010B1 (en) * 1995-06-05 2001-08-28 The Trustees Of The University Of Pennsylvania Adenovirus gene therapy vehicle and cell line
US6974694B2 (en) 1995-06-07 2005-12-13 Advec, Inc. Adenoviruses for control of gene expression
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US6544523B1 (en) 1996-11-13 2003-04-08 Chiron Corporation Mutant forms of Fas ligand and uses thereof
IL133710A0 (en) 1997-06-30 2001-04-30 Rhone Poulence Rorer S A Improved method for transferring nucleic acid into the striped muscle and combination thereof
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Also Published As

Publication number Publication date
JPH06502771A (en) 1994-03-31
DE69230993T3 (en) 2004-12-16
GR3034094T3 (en) 2000-11-30
FR2681786B1 (en) 1995-05-12
ATE192500T1 (en) 2000-05-15
CA2097185A1 (en) 1993-03-28
AU2790292A (en) 1993-04-27
CA2097185C (en) 2007-07-24
SG49081A1 (en) 1998-05-18
EP0559884B2 (en) 2004-04-07
AU666142B2 (en) 1996-02-01
ES2147553T3 (en) 2000-09-16
DE69230993T2 (en) 2000-11-30
EP0559884B1 (en) 2000-05-03
DE69230993D1 (en) 2000-06-08
JP3487597B2 (en) 2004-01-19
WO1993006223A1 (en) 1993-04-01
ES2147553T5 (en) 2004-11-16
FR2681786A1 (en) 1993-04-02
EP0559884A1 (en) 1993-09-15
DK0559884T3 (en) 2000-10-02

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