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DK0516234T3 - Phenoxyphenylderivater - Google Patents

Phenoxyphenylderivater

Info

Publication number
DK0516234T3
DK0516234T3 DK92201484.0T DK92201484T DK0516234T3 DK 0516234 T3 DK0516234 T3 DK 0516234T3 DK 92201484 T DK92201484 T DK 92201484T DK 0516234 T3 DK0516234 T3 DK 0516234T3
Authority
DK
Denmark
Prior art keywords
phenoxyphenyl
ch2nr1r2
lives
dihydro
imidazole
Prior art date
Application number
DK92201484.0T
Other languages
English (en)
Inventor
Gerardus Stephanus Franc Ruigt
Johannes Hubertus Wieringa
Dirk Leysen
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK0516234T3 publication Critical patent/DK0516234T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/58Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
DK92201484.0T 1991-05-29 1992-05-25 Phenoxyphenylderivater DK0516234T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91201288 1991-05-29

Publications (1)

Publication Number Publication Date
DK0516234T3 true DK0516234T3 (da) 1996-01-29

Family

ID=8207675

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92201484.0T DK0516234T3 (da) 1991-05-29 1992-05-25 Phenoxyphenylderivater

Country Status (15)

Country Link
US (2) US5190965A (da)
EP (1) EP0516234B1 (da)
JP (1) JPH05148197A (da)
KR (1) KR920021493A (da)
AT (1) ATE127777T1 (da)
AU (1) AU650136B2 (da)
CA (1) CA2068373A1 (da)
DE (1) DE69204743T2 (da)
DK (1) DK0516234T3 (da)
ES (1) ES2079783T3 (da)
FI (1) FI922433L (da)
GR (1) GR3018357T3 (da)
IE (1) IE67144B1 (da)
NO (1) NO178395C (da)
ZA (1) ZA923283B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives
US5447948A (en) * 1992-05-07 1995-09-05 Yale University Dopamine and noradrenergic reuptake inhibitors in treatment of schizophrenia
EA004860B1 (ru) * 1999-02-23 2004-08-26 Пфайзер Продактс Инк. Ингибиторы обратного захвата моноаминов для лечения расстройств цнс
US7375125B2 (en) * 1999-08-04 2008-05-20 Ore Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
EP1204645A2 (en) * 1999-08-04 2002-05-15 Millennium Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
IL149105A0 (en) * 1999-10-13 2002-11-10 Pfizer Prodcts Inc Biaryl ether derivatives useful as monoamine reuptake inhibitors
US6410736B1 (en) 1999-11-29 2002-06-25 Pfizer Inc. Biaryl ether derivatives useful as monoamine reuptake inhibitors
GB0007884D0 (en) * 2000-03-31 2000-05-17 Pfizer Ltd Diphenyl ether compounds useful in therapy
US6448293B1 (en) 2000-03-31 2002-09-10 Pfizer Inc. Diphenyl ether compounds useful in therapy
US6548484B1 (en) 2000-04-12 2003-04-15 International Medical Innovations, Inc. Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation
US6630504B2 (en) 2000-08-31 2003-10-07 Pfizer Inc. Phenoxyphenylheterocyclyl derivatives as SSRIs
DE60119047D1 (de) * 2000-08-31 2006-06-01 Pfizer Phenoxyphenylheterozyklen als Serotonin-Wiederaufnahmehemmer
AU2001278650A1 (en) * 2000-08-31 2002-03-13 Pfizer Inc. Phenoxybenzylamine derivatives as selective serotonin re-uptake inhibitors
US6610747B2 (en) 2000-08-31 2003-08-26 Pfizer Inc. Phenoxybenzylamine derivatives as SSRIs
US6436938B1 (en) * 2001-01-22 2002-08-20 Pfizer Inc. Combination treatment for depression
US20020165217A1 (en) * 2001-05-01 2002-11-07 Pfizer Inc. Combination treatment for anxiety and depression
EP1260221A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination treatment for depression and anxiety
EP1262196A3 (en) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combination of a monoamine reuptake inhibitor and an opioid antagonist for use in alcoholism and alcohol dependence
US20020183306A1 (en) * 2001-05-30 2002-12-05 Pfizer Inc. Combination treatment for sleep disorders including sleep apnea
SI1572173T1 (sl) 2002-12-13 2010-08-31 Warner Lambert Co Alfa-2-delta ligand za zdravljenje simptomov spodnjega dela sečil
WO2007036781A1 (en) * 2005-09-30 2007-04-05 Pfizer Products Inc. Diphenyl ether monoamine reuptake inhibitor
EA017171B1 (ru) * 2006-12-22 2012-10-30 Рекордати Айерленд Лимитед КОМБИНИРОВАННАЯ ТЕРАПИЯ ЗАБОЛЕВАНИЙ НИЖНИХ МОЧЕВЫВОДЯЩИХ ПУТЕЙ С ИСПОЛЬЗОВАНИЕМ ЛИГАНДОВ αδ И НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ (НПВП)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579582A (en) * 1967-02-16 1971-05-18 Universal Oil Prod Co Hydroxy and/or hydrocarbyloxy and amino substituted tetrahydronaphthalenes
GB1187200A (en) * 1967-04-04 1970-04-08 Dow Chemical Co 2-[(Halophenoxy) Methyl]-2-Imidazolines
NL7013566A (da) * 1969-09-29 1971-03-31
US3996279A (en) * 1973-01-02 1976-12-07 Gerot-Pharmazeutika Dr. Walter Otto K.G. Novel 2-amino methyl-4,6-dihalogenphenol derivatives and methods for the preparation thereof
AT332863B (de) * 1973-01-02 1976-10-25 Gerot Pharmazeutika Verfahren zur herstellung von neuen 2-aminomethyl-4,6-dihalogenphenolderivaten sowie deren additionssalzen mit sauren
DE2403138A1 (de) * 1974-01-23 1975-07-31 Hoechst Ag Benzylaminderivate und verfahren zu ihrer herstellung
IE40911B1 (en) * 1974-04-11 1979-09-12 Schering Ag Imidazole derivatives and process for their manufacture
DE2418502C3 (de) * 1974-04-11 1980-04-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen Dichlorbenzyl- [2-( a -imidazolylbutyl)-phenyl] -äther und -thioäther, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4055665A (en) * 1974-11-25 1977-10-25 Merck & Co., Inc. Treating arrythmia with phenylthioaralkylamines
US3946119A (en) * 1974-12-23 1976-03-23 Sandoz, Inc. Optionally substituted α-tertiary butyl-p-phenoxybenzylamines and their use as hypolipidemic agents
US4151302A (en) * 1975-06-28 1979-04-24 Merck Patent Gesellschaft Mit Beschrankter Haftung Araliphatic dihalogen compounds composition and method of use
GB1561411A (en) * 1977-02-25 1980-02-20 Science Union & Cie 2-phenoxyphenyl pyrrolidines and pharmaceutical compositions containing them
JPS55104240A (en) * 1979-02-07 1980-08-09 Idemitsu Kosan Co Ltd N-(alpha,alpha-dimethylbenzyl)-acetamide derivative and herbicide containing the same
JPS56108752A (en) * 1980-01-28 1981-08-28 Sumitomo Chem Co Ltd N-substituted benzylphenylacetamide derivative, its preparation and herbicide containing the same as active constituent
US5149714A (en) * 1987-08-14 1992-09-22 Merrell Dow Pharmaceuticals Inc. Antidepressants
JPH0791249B2 (ja) * 1988-11-10 1995-10-04 北興化学工業株式会社 メタアリールオキシアラルキルアミン誘導体および除草剤
JPH07103079B2 (ja) * 1988-11-21 1995-11-08 北興化学工業株式会社 パラアリールオキシアラルキルアミン誘導体および殺虫・殺ダニ剤
ZA899033B (en) * 1988-12-01 1990-09-26 Merrell Dow Pharma Phenoxy and phenylthio,amino substituted benzocycloalkane derivatives in the treatment and prevention of drug-resistant protozoal infections
ZA923283B (en) * 1991-05-29 1993-01-27 Akzo Nv Phenoxyphenyl derivatives

Also Published As

Publication number Publication date
FI922433A0 (fi) 1992-05-27
US5430063A (en) 1995-07-04
NO178395C (no) 1996-03-20
ES2079783T3 (es) 1996-01-16
NO178395B (no) 1995-12-11
FI922433L (fi) 1992-11-30
AU1710492A (en) 1992-12-03
IE921422A1 (en) 1992-12-02
JPH05148197A (ja) 1993-06-15
EP0516234B1 (en) 1995-09-13
DE69204743T2 (de) 1996-04-04
US5190965A (en) 1993-03-02
EP0516234A1 (en) 1992-12-02
KR920021493A (ko) 1992-12-18
AU650136B2 (en) 1994-06-09
NO922110L (no) 1992-11-30
IE67144B1 (en) 1996-03-06
ATE127777T1 (de) 1995-09-15
CA2068373A1 (en) 1992-11-30
DE69204743D1 (de) 1995-10-19
GR3018357T3 (en) 1996-03-31
NO922110D0 (no) 1992-05-27
ZA923283B (en) 1993-01-27

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