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DK0424248T3 - 20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf - Google Patents

20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf

Info

Publication number
DK0424248T3
DK0424248T3 DK90402898.2T DK90402898T DK0424248T3 DK 0424248 T3 DK0424248 T3 DK 0424248T3 DK 90402898 T DK90402898 T DK 90402898T DK 0424248 T3 DK0424248 T3 DK 0424248T3
Authority
DK
Denmark
Prior art keywords
optionally substituted
radical
carbon atoms
alkenyl
alkyl
Prior art date
Application number
DK90402898.2T
Other languages
English (en)
Inventor
Francois Clemence
Claude Oberlander
Jean-Luc Haesslein
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of DK0424248T3 publication Critical patent/DK0424248T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90402898.2T 1989-10-17 1990-10-16 20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf DK0424248T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8913544A FR2653124B1 (fr) 1989-10-17 1989-10-17 Nouveaux derives substitues en 15 de la 20, 21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant.

Publications (1)

Publication Number Publication Date
DK0424248T3 true DK0424248T3 (da) 1996-03-04

Family

ID=9386471

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90402898.2T DK0424248T3 (da) 1989-10-17 1990-10-16 20,21-dinoreburnamein med substitution i 15-stillingen, fremgangsmåde til deres fremstilling samt mellemprodukter til brug derved, deres anvendelse som lægemidler og præparater med indhold deraf

Country Status (19)

Country Link
US (1) US6534515B2 (da)
EP (1) EP0424248B1 (da)
JP (1) JPH03133981A (da)
KR (1) KR0180706B1 (da)
CN (1) CN1040000C (da)
AT (1) ATE132867T1 (da)
AU (1) AU646817B2 (da)
CA (1) CA2027724A1 (da)
DE (1) DE69024745T2 (da)
DK (1) DK0424248T3 (da)
ES (1) ES2081957T3 (da)
FR (1) FR2653124B1 (da)
GR (1) GR3018736T3 (da)
HU (1) HU218937B (da)
IE (1) IE71209B1 (da)
MX (1) MX22863A (da)
PT (1) PT95600B (da)
RU (1) RU2069663C1 (da)
ZA (1) ZA907832B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2865649A1 (fr) * 2004-01-30 2005-08-05 Biocortech Utilisation du 14,15-dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures
FR2865650B1 (fr) * 2004-01-30 2008-06-13 Biocortech Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR22021E (fr) * 1919-12-30 1921-04-21 Dujardin Et Cie Perfectionnements aux frappeurs pneumatiques
AU532001B2 (en) * 1978-11-20 1983-09-15 Sumitomo Chemical Company, Limited Polycyclic indole derivatives
FR2514357A1 (fr) * 1981-10-08 1983-04-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine eventuellement substitues sur le cycle e, procede de preparation et application comme medicaments
FR2623503B1 (da) * 1987-11-19 1991-04-05 Roussel Uclaf
FR2623501B1 (fr) * 1987-11-19 1990-03-16 Roussel Uclaf Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
HU218937B (hu) 2001-01-29
HUT55013A (en) 1991-04-29
CN1051042A (zh) 1991-05-01
ES2081957T3 (es) 1996-03-16
ATE132867T1 (de) 1996-01-15
AU646817B2 (en) 1994-03-10
FR2653124B1 (fr) 1992-01-17
PT95600A (pt) 1991-09-13
KR0180706B1 (ko) 1999-03-20
AU6466890A (en) 1991-04-26
FR2653124A1 (fr) 1991-04-19
DE69024745D1 (de) 1996-02-22
CA2027724A1 (fr) 1991-04-18
ZA907832B (en) 1991-12-24
EP0424248A2 (fr) 1991-04-24
US20020045637A1 (en) 2002-04-18
HU906462D0 (en) 1991-04-29
EP0424248B1 (fr) 1996-01-10
RU2069663C1 (ru) 1996-11-27
IE903702A1 (en) 1991-04-24
MX22863A (es) 1993-11-01
PT95600B (pt) 1997-08-29
KR910007930A (ko) 1991-05-30
JPH03133981A (ja) 1991-06-07
IE71209B1 (en) 1997-02-12
US6534515B2 (en) 2003-03-18
DE69024745T2 (de) 1996-11-14
EP0424248A3 (en) 1992-01-22
CN1040000C (zh) 1998-09-30
GR3018736T3 (en) 1996-04-30

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