DK0420121T3 - Antitumormiddel - Google Patents
AntitumormiddelInfo
- Publication number
- DK0420121T3 DK0420121T3 DK90118339.2T DK90118339T DK0420121T3 DK 0420121 T3 DK0420121 T3 DK 0420121T3 DK 90118339 T DK90118339 T DK 90118339T DK 0420121 T3 DK0420121 T3 DK 0420121T3
- Authority
- DK
- Denmark
- Prior art keywords
- antitumor agent
- chem
- compound
- formula
- pharmaceutically acceptable
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1251534A JP2919867B2 (ja) | 1989-09-27 | 1989-09-27 | 抗腫瘍剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0420121T3 true DK0420121T3 (da) | 1993-05-03 |
Family
ID=17224245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90118339.2T DK0420121T3 (da) | 1989-09-27 | 1990-09-25 | Antitumormiddel |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0420121B1 (ko) |
| JP (1) | JP2919867B2 (ko) |
| KR (1) | KR970008106B1 (ko) |
| AT (1) | ATE86866T1 (ko) |
| CA (1) | CA2025857A1 (ko) |
| DE (1) | DE69001111T2 (ko) |
| DK (1) | DK0420121T3 (ko) |
| ES (1) | ES2046641T3 (ko) |
| GR (1) | GR3007401T3 (ko) |
| RU (1) | RU2027442C1 (ko) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5599903A (en) * | 1992-04-03 | 1997-02-04 | Terrapin Technologies, Inc. | Glutathione analogs and paralog panels comprising glutathione mimics |
| DE69122831T2 (de) * | 1990-04-26 | 1997-03-27 | Senju Pharma Co | S-(niedere fettsäuren)-substituierte glutathionderivate |
| US5556942A (en) * | 1991-04-29 | 1996-09-17 | Terrapin Technologies, Inc. | Glutathione S-transferase-activated compounds |
| FR2698543B1 (fr) * | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
| US5908919A (en) * | 1993-10-01 | 1999-06-01 | Terrapin Technologies | Urethane mediated, GST specific molecular release systems |
| US5880097A (en) * | 1996-01-04 | 1999-03-09 | Terrapin Techologies, Inc. | Tethered prodrugs |
| GB0011059D0 (en) | 2000-05-08 | 2000-06-28 | Pharmacia & Upjohn Spa | Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione |
| GB0015446D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites |
| GB0015447D0 (en) | 2000-06-23 | 2000-08-16 | Pharmacia & Upjohn Spa | Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents |
| GB0016447D0 (en) | 2000-07-04 | 2000-08-23 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| IT1318696B1 (it) | 2000-09-15 | 2003-08-27 | Pharmacia & Upjohn Spa | Coniugati di glutatione con derivati della distamicina ad attivita'antitumorale. |
| GB0029004D0 (en) | 2000-11-28 | 2001-01-10 | Pharmacia & Upjohn Spa | Process for preparing distamycin derivatives |
| US6969592B2 (en) | 2001-09-26 | 2005-11-29 | Pharmacia Italia S.P.A. | Method for predicting the sensitivity to chemotherapy |
| RU2282438C1 (ru) * | 2005-03-24 | 2006-08-27 | Александра Петровна Безрукова | Средство, обладающее противоопухолевой активностью |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE788945A (ko) | 1971-09-20 | 1973-03-19 | Oreal | |
| DE3722647A1 (de) * | 1987-07-09 | 1989-01-19 | Gerhard Ohlenschlaeger | Galenische verwendung eines tripeptids als arzneimittel |
-
1989
- 1989-09-27 JP JP1251534A patent/JP2919867B2/ja not_active Expired - Lifetime
-
1990
- 1990-09-20 CA CA002025857A patent/CA2025857A1/en not_active Abandoned
- 1990-09-25 DK DK90118339.2T patent/DK0420121T3/da active
- 1990-09-25 AT AT90118339T patent/ATE86866T1/de not_active IP Right Cessation
- 1990-09-25 ES ES199090118339T patent/ES2046641T3/es not_active Expired - Lifetime
- 1990-09-25 EP EP90118339A patent/EP0420121B1/en not_active Expired - Lifetime
- 1990-09-25 DE DE9090118339T patent/DE69001111T2/de not_active Expired - Fee Related
- 1990-09-26 RU SU904831461A patent/RU2027442C1/ru active
- 1990-09-27 KR KR1019900015378A patent/KR970008106B1/ko not_active Expired - Fee Related
-
1993
- 1993-03-18 GR GR930400515T patent/GR3007401T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2919867B2 (ja) | 1999-07-19 |
| DE69001111D1 (de) | 1993-04-22 |
| RU2027442C1 (ru) | 1995-01-27 |
| CA2025857A1 (en) | 1991-03-28 |
| EP0420121B1 (en) | 1993-03-17 |
| DE69001111T2 (de) | 1993-07-22 |
| KR970008106B1 (ko) | 1997-05-21 |
| ES2046641T3 (es) | 1994-02-01 |
| KR910005859A (ko) | 1991-04-27 |
| JPH03112933A (ja) | 1991-05-14 |
| ATE86866T1 (de) | 1993-04-15 |
| GR3007401T3 (ko) | 1993-07-30 |
| EP0420121A1 (en) | 1991-04-03 |
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