DK0413191T3 - 1-(Pyridinylamino)-2-pyrrolidinoner, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler - Google Patents

1-(Pyridinylamino)-2-pyrrolidinoner, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Info

Publication number: DK0413191T3
Authority: DK; Denmark
Prior art keywords: pyridinylamino; pyrrolidinones; loweralkyl; aryl; drugs
Prior art date: 1989-08-02

Application number

DK90114659.7T

Other languages

English (en)

Inventor

Richard Charles Dr Effland

David Gordon Dr Wettlaufer

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-02

Filing date

1990-07-31

Publication date

1994-10-24

1990-07-31 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1994-10-24 Application granted granted Critical

1994-10-24 Publication of DK0413191T3 publication Critical patent/DK0413191T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Hydrogenated Pyridines (AREA)

DK90114659.7T 1989-08-02 1990-07-31 1-(Pyridinylamino)-2-pyrrolidinoner, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler DK0413191T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/388,413 US4994472A (en)	1989-08-02	1989-08-02	1-(pyridinylamino)-2-pyrrolidinones as pain relievers

Publications (1)

Publication Number	Publication Date
DK0413191T3 true DK0413191T3 (da)	1994-10-24

Family

ID=23534027

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90114659.7T DK0413191T3 (da)	1989-08-02	1990-07-31	1-(Pyridinylamino)-2-pyrrolidinoner, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler

Country Status (17)

Country	Link
US (1)	US4994472A (da)
EP (1)	EP0413191B1 (da)
JP (1)	JPH0674264B2 (da)
KR (1)	KR0164437B1 (da)
AT (1)	ATE109142T1 (da)
AU (1)	AU635051B2 (da)
CA (1)	CA2022484C (da)
DE (1)	DE69011013T2 (da)
DK (1)	DK0413191T3 (da)
ES (1)	ES2059929T3 (da)
FI (1)	FI903818A0 (da)
IE (1)	IE65117B1 (da)
IL (1)	IL95250A (da)
NO (1)	NO903388L (da)
NZ (1)	NZ234724A (da)
PT (1)	PT94878B (da)
ZA (1)	ZA906049B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5356908A (en) *	1989-04-21	1994-10-18	E. I. Du Pont De Nemours And Company	Fungicidal oxazolidinones
OA09338A (fr) *	1989-12-27	1992-09-15	Monsanto Co	"Pyridines substituées".
AUPM656594A0 (en) *	1994-06-30	1994-07-21	Orbital Engine Company (Australia) Proprietary Limited	A method and apparatus relating to control of the operation of an internal combustion engine
BR9708655A (pt) *	1996-04-12	1999-08-03	Hoechst Marion Roussel Inc	Derivados de isatina como inibidores de acetilcolinesterase e analgésicos
US6100276A (en) *	1996-04-12	2000-08-08	Aventis Pharmaceuticals Inc.	Isatin derivatives as acetylcholinesterase inhibitors and analgesics
US20050065205A1 (en)	2002-03-07	2005-03-24	Daniel Alkon	Methods for Alzheimer's disease treatment and cognitive enhance
US6825229B2 (en)	2002-03-07	2004-11-30	Blanchette Rockefeller Neurosciences Institute	Methods for Alzheimer's Disease treatment and cognitive enhancement
KR20050094761A (ko) *	2002-07-02	2005-09-28	블랜체트 록펠러 뉴로사이언시즈 인스티튜트	브리오스타틴형 화합물을 사용한 ｓＡＰＰα 분비의 증진및 인지 개선을 위한 수단으로서의 ＰＫＣ 활성화
TW201206425A (en)	2004-05-18	2012-02-16	Brni Neurosciences Inst	Treatment of depressive disorders
GB0412019D0 (en) *	2004-05-28	2004-06-30	Novartis Ag	Organic compounds
US20070054890A1 (en)	2005-07-29	2007-03-08	Alkon Daniel L	Protein synthesis required for long-term memory is induced by PKC activation on days preceding associative learning
EP2754448A3 (en)	2007-02-09	2014-12-24	Blanchette Rockefeller Neurosciences, Institute	Therapeutic effects of bryostatins, bryologs, and other related substances on head trauma-induced memory impairment and brain injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670184A1 (de) *	1967-01-20	1971-01-21	Boehringer Sohn Ingelheim	Verfahren zur Herstellung heterocyclisch substituierter Hydrazino-imidazoline-(2)
US4260767A (en) *	1979-12-26	1981-04-07	American Cyanamid Company	2-Pyridylhydrazides
US4324884A (en) *	1980-09-25	1982-04-13	General Electric Company	Organic amine catalyzed method for making polyetherimide
US4752610A (en) *	1985-12-04	1988-06-21	Hoechst-Roussel Pharmaceuticals Inc.	N-(pyrrol-1-yl)pyridinamines having memory enhancing properties
US4792562A (en) *	1985-12-04	1988-12-20	Hoechst-Roussel Pharmaceuticals, Inc.	N-(pyrrol-1-yl)pyridinamines having memory enhancing activity
JPH0699307B2 (ja) *	1987-08-20	1994-12-07	キッセイ薬品工業株式会社	抗痴呆剤
US4868190A (en) *	1988-12-27	1989-09-19	Hoechst-Roussel Pharmaceuticals, Inc.	N-pyridinyl-9H-carbazol-9-amines

1989
- 1989-08-02 US US07/388,413 patent/US4994472A/en not_active Expired - Lifetime
1990
- 1990-07-31 DK DK90114659.7T patent/DK0413191T3/da active
- 1990-07-31 ES ES90114659T patent/ES2059929T3/es not_active Expired - Lifetime
- 1990-07-31 IL IL9525090A patent/IL95250A/en active IP Right Revival
- 1990-07-31 DE DE69011013T patent/DE69011013T2/de not_active Expired - Lifetime
- 1990-07-31 NZ NZ234724A patent/NZ234724A/en unknown
- 1990-07-31 EP EP90114659A patent/EP0413191B1/en not_active Expired - Lifetime
- 1990-07-31 AT AT90114659T patent/ATE109142T1/de not_active IP Right Cessation
- 1990-07-31 FI FI903818A patent/FI903818A0/fi not_active Application Discontinuation
- 1990-08-01 NO NO90903388A patent/NO903388L/no unknown
- 1990-08-01 AU AU60002/90A patent/AU635051B2/en not_active Ceased
- 1990-08-01 CA CA002022484A patent/CA2022484C/en not_active Expired - Fee Related
- 1990-08-01 PT PT94878A patent/PT94878B/pt not_active IP Right Cessation
- 1990-08-01 ZA ZA906049A patent/ZA906049B/xx unknown
- 1990-08-01 IE IE278690A patent/IE65117B1/en not_active IP Right Cessation
- 1990-08-01 JP JP2202617A patent/JPH0674264B2/ja not_active Expired - Lifetime
- 1990-08-01 KR KR1019900011816A patent/KR0164437B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
IE65117B1 (en)	1995-10-04
IE902786A1 (en)	1991-02-27
KR0164437B1 (ko)	1999-01-15
AU6000290A (en)	1991-02-07
KR910004597A (ko)	1991-03-29
ZA906049B (en)	1991-04-24
ATE109142T1 (de)	1994-08-15
US4994472A (en)	1991-02-19
PT94878B (pt)	1997-08-29
EP0413191A1 (en)	1991-02-20
DE69011013T2 (de)	1994-12-22
CA2022484A1 (en)	1991-02-03
JPH0674264B2 (ja)	1994-09-21
ES2059929T3 (es)	1994-11-16
IL95250A (en)	1994-01-25
DE69011013D1 (de)	1994-09-01
NZ234724A (en)	1992-01-29
PT94878A (pt)	1991-04-18
JPH0368572A (ja)	1991-03-25
EP0413191B1 (en)	1994-07-27
CA2022484C (en)	2000-10-17
IL95250A0 (en)	1991-06-10
NO903388L (no)	1991-02-04
FI903818A0 (fi)	1990-07-31
AU635051B2 (en)	1993-03-11
NO903388D0 (no)	1990-08-01

Publication	Publication Date	Title
AU6208990A (en)	1991-03-14	N-substituted-4-pyrimidinamines and pyrimidindiamines, a process for their preparation and their use as medicaments
DK0415102T3 (da)	1995-06-19	1,3-Dihydro-1-(pyridinylamino)-2H-indol-2-oner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
DK0413191T3 (da)	1994-10-24	1-(Pyridinylamino)-2-pyrrolidinoner, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
NO903390D0 (no)	1990-08-01	Fremgangsmaate for fremstilling av 2,3-dihydro-1-(pyridinylamino)-indoler og deres anvendelse som legemidler.