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DE69943048D1 - METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS - Google Patents

METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS

Info

Publication number
DE69943048D1
DE69943048D1 DE69943048T DE69943048T DE69943048D1 DE 69943048 D1 DE69943048 D1 DE 69943048D1 DE 69943048 T DE69943048 T DE 69943048T DE 69943048 T DE69943048 T DE 69943048T DE 69943048 D1 DE69943048 D1 DE 69943048D1
Authority
DE
Germany
Prior art keywords
epidermis
detection
biological factors
polynucleotide
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69943048T
Other languages
German (de)
Inventor
Lawrence A Rheins
Vera B Morhenn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dermtech International
Original Assignee
Dermtech International
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermtech International filed Critical Dermtech International
Application granted granted Critical
Publication of DE69943048D1 publication Critical patent/DE69943048D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006—Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Disclosed is a method for removing polynucleotide from the skin. This polynucleotide can be used to detect dermatitis and distinguish an irritant reaction from an allergic reaction by characterizing the polynucleotide according to the polypeptide which it encodes. Additionally, provided are methods for non-invasive isolation of samples from the skin as well as kits for use in the methods provided herein.
DE69943048T 1998-08-18 1999-08-17 METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS Expired - Lifetime DE69943048D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9702598P 1998-08-18 1998-08-18
PCT/US1999/019012 WO2000010579A1 (en) 1998-08-18 1999-08-17 Method for detection of biological factors in epidermis

Publications (1)

Publication Number Publication Date
DE69943048D1 true DE69943048D1 (en) 2011-01-27

Family

ID=22260397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69943048T Expired - Lifetime DE69943048D1 (en) 1998-08-18 1999-08-17 METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS

Country Status (13)

Country Link
US (7) US6949338B2 (en)
EP (1) EP1112077B1 (en)
JP (2) JP4476488B2 (en)
KR (1) KR100689725B1 (en)
AT (1) ATE491462T1 (en)
AU (1) AU754471B2 (en)
CA (1) CA2340673C (en)
DE (1) DE69943048D1 (en)
DK (1) DK1112077T3 (en)
ES (1) ES2358175T3 (en)
IL (3) IL141481A0 (en)
PT (1) PT1112077E (en)
WO (1) WO2000010579A1 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69943048D1 (en) * 1998-08-18 2011-01-27 Dermtech International San Diego METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS
DE10100127A1 (en) * 2001-01-03 2002-10-02 Henkel Kgaa Procedure for determining the homeostasis of the skin
DE10100121A1 (en) * 2001-01-03 2002-08-01 Henkel Kgaa Method for determining skin stress or skin aging in vitro
US6790179B2 (en) 2001-08-01 2004-09-14 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
WO2002095418A2 (en) * 2001-08-01 2002-11-28 Johnson & Johnson Consumer Companies, Inc. Method of examining and diagnosing skin health
US6840910B2 (en) 2001-08-01 2005-01-11 Johnson & Johnson Consumer Companies, Inc. Method of distributing skin care products
US6855117B2 (en) 2001-08-01 2005-02-15 Johnson & Johnson Consumer Companies, Inc. Method of treating the skin of a subject
AU2002346008A1 (en) * 2001-06-28 2003-03-03 Dermtech International Method for detection of melanoma
EP1474685A2 (en) * 2002-02-12 2004-11-10 Biotesys Gmbh Analysis of vital substances
DE10229981A1 (en) * 2002-07-03 2004-02-05 Henkel Kgaa Procedure for the identification of infection-specific regulated genes of the skin
US20040219537A1 (en) * 2003-05-02 2004-11-04 Fenrich Richard K. Epidermal collection method, kit, and device
US7183057B2 (en) * 2004-03-31 2007-02-27 Dermtech International Tape stripping methods for analysis of skin disease and pathological skin state
US7238494B2 (en) 2004-04-30 2007-07-03 Imi International Medical Innovations, Inc. Direct assay of cholesterol in skin samples removed by tape stripping
US20050272112A1 (en) * 2004-04-28 2005-12-08 Imi International Medical Innovations, Inc. Direct assay of cholesterol in skin removed by tape stripping
US20070059679A1 (en) * 2005-09-09 2007-03-15 Michelle Garay Method for demonstrating efficacy of a topically applied active ingredient
US20070059268A1 (en) * 2005-09-09 2007-03-15 Laura Magee Compositions, methods and kits for treating allergic dermatitis of skin
US20070281314A1 (en) * 2006-04-20 2007-12-06 Dermtech International Methods for capture and detection of micro-RNA molecules from the skin by non-invasive tape stripping
US20080187502A1 (en) * 2007-02-02 2008-08-07 Michelle Garay Assessment and mitigation of oxidative stress in skin
EP2363505A3 (en) * 2007-05-04 2011-12-21 Dermtech International Diagnosis of melanoma by nucleic acid analysis
WO2008154532A1 (en) * 2007-06-11 2008-12-18 California Pacific Medical Center Method and kit for dynamic gene expression monitoring
CA2724322C (en) 2008-05-14 2019-07-16 Dermtech International Diagnosis of melanoma and solar lentigo by nucleic acid analysis
EP2977469A1 (en) 2008-08-28 2016-01-27 Dermtech International Determining age ranges of skin samples
ES2716402T3 (en) 2008-11-03 2019-06-12 Kapa Biosystems Inc Chimeric DNA polymerases
EP2478088B1 (en) * 2009-09-16 2016-08-31 Life Technologies Corporation Lysis buffers for extracting nucleic acids
US8420054B2 (en) * 2009-09-18 2013-04-16 The Procter & Gamble Company Noninvasive method for measuring histamine from skin as an objective measurement of itch
DE102009043485A1 (en) 2009-09-30 2011-03-31 Henkel Ag & Co. Kgaa Diagnosing chronic stress in organisms comprises providing sample from hair follicles, determining expression of a marker for chronic stress, optionally determining e.g. expression of further marker for stress, and correlating the results
DE102009046128A1 (en) 2009-10-29 2010-08-05 Henkel Ag & Co. Kgaa Non-invasive method for screening of active agent/formulation against skin aging in vivo, comprises contacting human with agent/formulation, applying adhesive tape to skin and tearing off, extracting the biological material and detecting
EP3752645A4 (en) 2018-02-14 2022-04-13 Dermtech, Inc. NEW GENE CLASSIFIERS AND THEIR USE IN NON-MELANOMA SKIN CANCER
KR20210031640A (en) 2018-05-09 2021-03-22 덤테크, 인크. Novel gene classifiers and their use in autoimmune diseases
GB2576374A (en) 2018-08-17 2020-02-19 Ecole Polytechnique Fed Lausanne Epfl Skin cell analysis
WO2020198229A1 (en) 2019-03-26 2020-10-01 Dermtech, Inc. Novel gene classifiers and uses thereof in skin cancers
IT202000030071A1 (en) * 2020-12-15 2021-03-15 Service Biotech S R L Creation of a dermatological signaling device similar to a patch test for the identification of allergic reactions to medicines, prior to administration to the patient.
USD966299S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD966300S1 (en) 2021-02-16 2022-10-11 Dermtech, Inc. Computer display panel with a graphical user interface for a dermatology report
USD989861S1 (en) 2021-02-16 2023-06-20 Dermtech, Inc. Dermatology report document
USD988399S1 (en) 2021-02-16 2023-06-06 Dermtech, Inc. Dermatology report document
EP4363604A1 (en) * 2021-06-30 2024-05-08 Ampel Biosolutions, LLC Methods and systems for machine learning analysis of inflammatory skin diseases
USD1061554S1 (en) 2022-09-09 2025-02-11 Dermtech, Llc Computer display panel with a graphical user interface for a dermatology report

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DE3247264A1 (en) * 1982-12-21 1984-06-28 Siemens AG, 1000 Berlin und 8000 München BIFOCAL PACEMAKER WITH TWO UNIPOLAR ELECTRODES
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4560939A (en) * 1984-04-02 1985-12-24 Sperry Corporation Synchronized selectable rate clocking system
SE8404895L (en) * 1984-10-01 1986-03-17 Torkel Ingemar Fischer MEANS OF A SENSITIVITY TEST
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5460939A (en) * 1986-04-18 1995-10-24 Advanced Tissue Sciences, Inc. Temporary living skin replacement
US4971800A (en) 1988-07-08 1990-11-20 The Regents Of The University Of California Method and compositions for enhancing the cutaneous penetration of pharmacologically active agents
US5583032A (en) * 1992-10-21 1996-12-10 The Cleveland Clinic Foundation And National Institutes Of Health Method of cleaving specific strands of RNA
US5753612A (en) * 1992-10-27 1998-05-19 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Pharmaceutical composition and method for inhibiting hair growth by administration of activin or activin agonists
JP3262443B2 (en) * 1994-01-12 2002-03-04 ポーラ化成工業株式会社 Method for measuring the degree of skin keratinocyte damage
JP3453871B2 (en) * 1994-08-31 2003-10-06 株式会社資生堂 Evaluation method of desmosome function
US6054277A (en) * 1996-05-08 2000-04-25 Regents Of The University Of Minnesota Integrated microchip genetic testing system
US5811239A (en) * 1996-05-13 1998-09-22 Frayne Consultants Method for single base-pair DNA sequence variation detection
US6056859A (en) * 1997-02-12 2000-05-02 Lockheed Martin Energy Research Corporation Method and apparatus for staining immobilized nucleic acids
DE69943048D1 (en) * 1998-08-18 2011-01-27 Dermtech International San Diego METHOD FOR THE DETECTION OF BIOLOGICAL FACTORS IN EPIDERMIS
KR100326937B1 (en) * 1998-09-23 2002-03-13 정연보 A method to obtain human skin DNA samples with an adhesive sheet

Also Published As

Publication number Publication date
US20020110824A1 (en) 2002-08-15
JP2002523145A (en) 2002-07-30
EP1112077B1 (en) 2010-12-15
ES2358175T3 (en) 2011-05-06
KR20010089165A (en) 2001-09-29
IL141481A (en) 2009-02-11
AU5575499A (en) 2000-03-14
DK1112077T3 (en) 2011-04-04
JP4476488B2 (en) 2010-06-09
US6949338B2 (en) 2005-09-27
US20020197604A1 (en) 2002-12-26
CA2340673C (en) 2013-11-12
US20020119471A1 (en) 2002-08-29
US20020150918A1 (en) 2002-10-17
US6720145B2 (en) 2004-04-13
IL141481A0 (en) 2002-03-10
AU754471B2 (en) 2002-11-14
PT1112077E (en) 2011-03-16
US20020115086A1 (en) 2002-08-22
US20020127573A1 (en) 2002-09-12
CA2340673A1 (en) 2000-03-02
JP2007029106A (en) 2007-02-08
EP1112077A4 (en) 2003-08-27
EP1112077A1 (en) 2001-07-04
WO2000010579A1 (en) 2000-03-02
IL194772A (en) 2012-12-31
KR100689725B1 (en) 2007-03-09
ATE491462T1 (en) 2011-01-15
US20020110822A1 (en) 2002-08-15

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