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DE69938645D1 - Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung - Google Patents

Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung

Info

Publication number
DE69938645D1
DE69938645D1 DE69938645T DE69938645T DE69938645D1 DE 69938645 D1 DE69938645 D1 DE 69938645D1 DE 69938645 T DE69938645 T DE 69938645T DE 69938645 T DE69938645 T DE 69938645T DE 69938645 D1 DE69938645 D1 DE 69938645D1
Authority
DE
Germany
Prior art keywords
optically active
acid derivatives
carboxylic acid
benzodioxin
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69938645T
Other languages
English (en)
Inventor
Koji Kawamura
Masahiro Ueno
Masashi Suzuki
Makoto Yanai
Toshihiro Takahashi
Koichi Itoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Pharma Inc
Original Assignee
Nisshin Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Pharma Inc filed Critical Nisshin Pharma Inc
Application granted granted Critical
Publication of DE69938645D1 publication Critical patent/DE69938645D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69938645T 1998-07-31 1999-07-23 Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung Expired - Fee Related DE69938645D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21782998 1998-07-31
PCT/JP1999/003963 WO2000006562A1 (en) 1998-07-31 1999-07-23 Optically active 1,4-benzodioxine-2-carboxylic acid derivatives and process for producing the same

Publications (1)

Publication Number Publication Date
DE69938645D1 true DE69938645D1 (de) 2008-06-19

Family

ID=16710410

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69938645T Expired - Fee Related DE69938645D1 (de) 1998-07-31 1999-07-23 Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung

Country Status (8)

Country Link
US (3) US6222050B1 (de)
EP (1) EP1020458B1 (de)
KR (1) KR100523713B1 (de)
AT (1) ATE394390T1 (de)
CA (1) CA2303195C (de)
DE (1) DE69938645D1 (de)
TW (1) TW531536B (de)
WO (1) WO2000006562A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69938645D1 (de) * 1998-07-31 2008-06-19 Nisshin Pharma Inc Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung
US7241272B2 (en) 2001-11-13 2007-07-10 Baxter International Inc. Method and composition for removing uremic toxins in dialysis processes
WO2004070045A1 (ja) * 2003-02-10 2004-08-19 Nisshin Pharma Inc. 光学活性な６－ホルミル－１,４－ベンゾジオキシン－２－カルボン酸誘導体の製造方法
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
WO2005083102A1 (ja) * 2004-03-01 2005-09-09 Mercian Corporation 光学活性1,4-ベンゾジオキシン-2-カルボン酸誘導体の製造方法
US8057423B2 (en) * 2007-07-05 2011-11-15 Baxter International Inc. Dialysis system having disposable cassette
US8114276B2 (en) * 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
US9415150B2 (en) * 2007-11-09 2016-08-16 Baxter Healthcare S.A. Balanced flow dialysis machine
CN105541537B (zh) * 2016-03-28 2018-01-23 山东成泰化工有限公司 一种调整碳四烯烃异构反应选择性的调节剂及方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4118507A (en) * 1977-03-17 1978-10-03 Shell Oil Company Benzodioxincarboxamide lipogenesis inhibitors
US4208424A (en) * 1979-04-26 1980-06-17 Shell Oil Company Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids
FR2704857B1 (fr) * 1993-05-07 1995-06-23 Adir Nouvelles benzodioxines substituées, leur procédé de préparation et les compositions pharmaceutiques les contenant.
US5482971A (en) * 1993-10-01 1996-01-09 American Cyanamid Company Beta3 -adrenergic agents and their use in pharmaceutical compositions
DE69618634T2 (de) 1995-05-12 2002-06-20 Nisshin Pharma Inc., Tokio/Tokyo 1,4-benzodioxin-derivate
AU5723098A (en) * 1996-12-30 1998-07-31 American Home Products Corporation Substituted benzo{1,4}dioxanes as antiobesity agents
JP4233135B2 (ja) * 1997-11-11 2009-03-04 日清ファルマ株式会社 ６−（２−（ｒ）−アミノプロピル）−１，４−ベンゾジオキサン−２−（ｒ）−カルボン酸誘導体およびその製造方法
DE69938645D1 (de) * 1998-07-31 2008-06-19 Nisshin Pharma Inc Optisch aktive 1,4-benzodioxin-2-carbonsäure-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
KR100523713B1 (ko) 2005-10-26
US6329533B2 (en) 2001-12-11
US6509482B2 (en) 2003-01-21
US6222050B1 (en) 2001-04-24
KR20010024367A (ko) 2001-03-26
ATE394390T1 (de) 2008-05-15
CA2303195C (en) 2008-01-15
US20020028957A1 (en) 2002-03-07
CA2303195A1 (en) 2000-02-10
WO2000006562A1 (en) 2000-02-10
EP1020458B1 (de) 2008-05-07
TW531536B (en) 2003-05-11
US20010018529A1 (en) 2001-08-30
EP1020458A1 (de) 2000-07-19
EP1020458A4 (de) 2004-09-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee