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DE69916492D1 - Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen - Google Patents

Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen

Info

Publication number
DE69916492D1
DE69916492D1 DE69916492T DE69916492T DE69916492D1 DE 69916492 D1 DE69916492 D1 DE 69916492D1 DE 69916492 T DE69916492 T DE 69916492T DE 69916492 T DE69916492 T DE 69916492T DE 69916492 D1 DE69916492 D1 DE 69916492D1
Authority
DE
Germany
Prior art keywords
drug
volatile
plaster
active substances
liquid active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69916492T
Other languages
English (en)
Other versions
DE69916492T3 (de
DE69916492T2 (de
Inventor
J Miranda
C J Ii Betlach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
J. DEV LTD., ATHLONE, ROSCOMMON, IE
Original Assignee
Elan Pharma International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22337613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69916492(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Pharma International Ltd filed Critical Elan Pharma International Ltd
Application granted granted Critical
Publication of DE69916492D1 publication Critical patent/DE69916492D1/de
Publication of DE69916492T2 publication Critical patent/DE69916492T2/de
Publication of DE69916492T3 publication Critical patent/DE69916492T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69916492T 1998-12-07 1999-12-07 Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen Expired - Lifetime DE69916492T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11128598P 1998-12-07 1998-12-07
US111285P 1998-12-07
PCT/US1999/028697 WO2000033812A2 (en) 1998-12-07 1999-12-07 Transdermal patch for delivering volatile liquid drugs

Publications (3)

Publication Number Publication Date
DE69916492D1 true DE69916492D1 (de) 2004-05-19
DE69916492T2 DE69916492T2 (de) 2005-05-12
DE69916492T3 DE69916492T3 (de) 2008-08-14

Family

ID=22337613

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916492T Expired - Lifetime DE69916492T3 (de) 1998-12-07 1999-12-07 Pflaster zur transdermalen applikation von flüchtigen, flüssigen wirkstoffen

Country Status (9)

Country Link
EP (1) EP1137406B2 (de)
JP (1) JP2002531488A (de)
KR (1) KR100885235B1 (de)
AT (1) ATE264098T1 (de)
AU (1) AU778992B2 (de)
CA (1) CA2380391A1 (de)
DE (1) DE69916492T3 (de)
NZ (2) NZ525878A (de)
WO (1) WO2000033812A2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060002949A1 (en) 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20030170195A1 (en) 2000-01-10 2003-09-11 Noven Pharmaceuticals, Inc. Compositions and methods for drug delivery
WO2000041538A2 (en) 1999-01-14 2000-07-20 Noven Pharmaceuticals, Inc. Dermal compositions
CA2437899C (en) 2001-02-13 2012-05-15 Gregory M. Glenn Vaccine for transcutaneous immunization against etec-caused traveler's diarrhea
DE10110391A1 (de) 2001-03-03 2002-09-26 Lohmann Therapie Syst Lts Hochflexibles Nikotin transdermales therapeutisches System mit Nikotin als Wirkstoff
JP2004525921A (ja) * 2001-03-19 2004-08-26 イオマイ コーポレイシヨン 経皮免疫用パッチ
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
US20040086551A1 (en) 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
US20040209961A1 (en) * 2003-03-14 2004-10-21 John Devane Treatment of intestinal conditions with N-2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine
US20070224284A1 (en) 2004-03-12 2007-09-27 John Devane Methods and compositions comprising at least one alpha3 beta4 nAChR antagonist or pharmaceutically acceptable salt thereof
WO2005025549A2 (en) 2003-09-10 2005-03-24 Noven Pharmaceuticals, Inc. Multi-layer transdermal drug delivery device
ES2626784T3 (es) 2003-10-28 2017-07-26 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos
ITMI20041697A1 (it) * 2004-09-03 2004-12-03 Bouty S P A Sistema terapeutico a rilascio controllato per uso topico in forma di cerotto multistrato
US8343538B2 (en) 2004-10-08 2013-01-01 Noven Pharmaceuticals, Inc. Compositions and methods for controlling the flux of a drug from a transdermal drug delivery systems
US20060078602A1 (en) 2004-10-08 2006-04-13 Noven Pharmaceuticals, Inc. Device for transdermal administration of drugs including acrylic polymers
IL177071A0 (en) 2005-08-01 2006-12-10 Nitto Denko Corp Method of preparing a nicotine transdermal preparation
EP1774964B1 (de) 2005-10-13 2014-08-06 Nitto Denko Corporation Nikotinhaltiges transdermales therapeutisches System und dessen Herstellung
DE102006054733A1 (de) 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
AU2009300184A1 (en) * 2008-09-30 2010-04-08 Teikoku Pharma Usa, Inc. Transdermal extended-delivery donepezil compositions and methods for using the same
EP2298277A1 (de) * 2009-09-09 2011-03-23 Labtec GmbH Transdermale Pflasterformulierung
EA023786B1 (ru) 2010-04-30 2016-07-29 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Трансдермальные композиции на основе пропиниламиноиндана
US9119799B2 (en) 2011-03-24 2015-09-01 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
EP2776020B1 (de) 2011-11-09 2019-09-11 Teikoku Seiyaku Co., Ltd. Verfahren zur behandlung von neoplasmen der haut
KR20150059177A (ko) 2012-11-02 2015-05-29 테이코쿠 팔마 유에스에이, 인코포레이티드 프로피닐아미노인단 경피 조성물
DE102013013397A1 (de) 2013-08-13 2015-03-12 Epinamics Gmbh Aerosolspender für transdermal wirkende pharmazeutische Zusammensetzungen
DE102013020633A1 (de) 2013-12-16 2015-06-18 Epinamics Gmbh Dermale und/oder transdermale pharmazeutische Zusammensetzung enthaltend eine terpenoide Verbindung
DE102020112143B4 (de) 2020-05-05 2022-03-17 Lts Lohmann Therapie-Systeme Ag Nicotin - Corona

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4717568A (en) * 1985-08-09 1988-01-05 Alza Corporation Laminar arrangement for increasing delivery of beneficial agent from dispenser
US5316759A (en) † 1986-03-17 1994-05-31 Robert J. Schaap Agonist-antagonist combination to reduce the use of nicotine and other drugs
DE3629304A1 (de) † 1986-08-28 1988-03-24 Lohmann Gmbh & Co Kg Transdermales therapeutisches system, seine verwendung und verfahren zu seiner herstellung
CH674618A5 (de) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
GB8807504D0 (en) † 1988-03-29 1988-05-05 Sandoz Ltd Improvements in/relating to organic compounds
DE3908432A1 (de) * 1989-03-14 1990-09-27 Lohmann Therapie Syst Lts Pflaster als therapeutisches system zur verabreichung von wirkstoffen an die haut mit einer abgestuften wirkstoffabgabe, verfahren zu seiner herstellung sowie verwendung
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
EP0708627B1 (de) † 1993-07-09 2000-02-02 Cygnus, Inc. Verfahren und vorrichtung für die transdermale oder transbuccale therapeutische verabreichung von nikotinsubstituten
DE4332094C2 (de) † 1993-09-22 1995-09-07 Lohmann Therapie Syst Lts Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung
CA2183083C (en) * 1994-03-07 2006-01-03 Charles D. Ebert Drug-containing adhesive composite transdermal delivery device
NZ309980A (en) * 1995-06-07 2001-06-29 Noven Pharma Transdermal composition containing a blend of one or more polymers, one or more drugs that has a low molecular weight and is liquid at room temperature
US5691365A (en) * 1995-07-18 1997-11-25 University Of Kentucky Research Foundation Nicotinic receptor antagonists in the treatment of neuropharmacological disorders
JPH09301853A (ja) * 1996-05-14 1997-11-25 Nitto Denko Corp 貼付剤および貼付製剤

Also Published As

Publication number Publication date
DE69916492T3 (de) 2008-08-14
WO2000033812A2 (en) 2000-06-15
WO2000033812A3 (en) 2000-11-23
DE69916492T2 (de) 2005-05-12
JP2002531488A (ja) 2002-09-24
AU778992B2 (en) 2004-12-23
NZ525878A (en) 2004-12-24
EP1137406B2 (de) 2008-01-23
EP1137406B1 (de) 2004-04-14
KR20010101147A (ko) 2001-11-14
AU2587700A (en) 2000-06-26
EP1137406A2 (de) 2001-10-04
NZ512788A (en) 2003-07-25
KR100885235B1 (ko) 2009-02-24
CA2380391A1 (en) 2000-06-15
ATE264098T1 (de) 2004-04-15

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: J. DEV LTD., ATHLONE, ROSCOMMON, IE

8366 Restricted maintained after opposition proceedings