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DE69838986D1 - Polypeptide, deren herstellung und verwendung - Google Patents

Polypeptide, deren herstellung und verwendung

Info

Publication number
DE69838986D1
DE69838986D1 DE69838986T DE69838986T DE69838986D1 DE 69838986 D1 DE69838986 D1 DE 69838986D1 DE 69838986 T DE69838986 T DE 69838986T DE 69838986 T DE69838986 T DE 69838986T DE 69838986 D1 DE69838986 D1 DE 69838986D1
Authority
DE
Germany
Prior art keywords
function
polypeptides
preparation
aids
diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69838986T
Other languages
English (en)
Other versions
DE69838986T2 (de
Inventor
Shuji Hinuma
Kazuhiko Tatemoto
Masaki Hosoya
Yugo Habata
Ryo Fujii
Chieko Kitada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69838986D1 publication Critical patent/DE69838986D1/de
Publication of DE69838986T2 publication Critical patent/DE69838986T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69838986T 1997-12-24 1998-12-22 Polypeptide, deren herstellung und verwendung Expired - Lifetime DE69838986T2 (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP35395597 1997-12-24
JP35395597 1997-12-24
JP3257798 1998-02-16
JP3257798 1998-02-16
JP22085398 1998-08-04
JP22085398 1998-08-04
JP27164598 1998-09-25
JP27164598 1998-09-25
PCT/JP1998/005805 WO1999033976A1 (en) 1997-12-24 1998-12-22 Polypeptide, their production and use

Publications (2)

Publication Number Publication Date
DE69838986D1 true DE69838986D1 (de) 2008-02-21
DE69838986T2 DE69838986T2 (de) 2009-01-08

Family

ID=27459639

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69838986T Expired - Lifetime DE69838986T2 (de) 1997-12-24 1998-12-22 Polypeptide, deren herstellung und verwendung

Country Status (9)

Country Link
US (3) US6492324B1 (de)
EP (1) EP1040189B1 (de)
KR (1) KR20010033601A (de)
CN (1) CN1283228A (de)
AT (1) ATE383424T1 (de)
AU (1) AU1685499A (de)
CA (1) CA2313246A1 (de)
DE (1) DE69838986T2 (de)
WO (1) WO1999033976A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1062337B1 (de) * 1998-03-13 2011-11-09 Brown University Research Foundation Isoform des humanen n-artigen calciumkanals und dessen verwendungen
AU5759399A (en) * 1998-09-25 2000-04-17 Takeda Chemical Industries Ltd. Peptide derivative
EP1138772A4 (de) * 1998-12-11 2005-04-06 Takeda Chemical Industries Ltd Verfahren zur herstellung von apelin
CN1419563A (zh) * 2000-03-23 2003-05-21 武田药品工业株式会社 肽衍生物
DE10138569A1 (de) * 2001-08-06 2003-04-30 Bayer Ag Regulation des APJ-Rezeptors
WO2003063892A1 (fr) * 2002-01-29 2003-08-07 Takeda Chemical Industries, Ltd. Utilisation d'apeline
US20060073484A1 (en) 2002-12-30 2006-04-06 Mathies Richard A Methods and apparatus for pathogen detection and analysis
US7342105B2 (en) 2003-02-28 2008-03-11 Takeda Chemcial Industries, Ltd. Antibody and use thereof
DE602004027798D1 (de) * 2003-03-12 2010-08-05 Univ Arizona State Verfahren zur regulierung von angiogenese mit apelin-zusammensetzungen
US7947280B2 (en) * 2003-05-22 2011-05-24 The Board Of Trustees Of The Leland Stanford Junior University Apelin and uses thereof
WO2006019193A1 (ja) * 2004-08-20 2006-02-23 Takeda Pharmaceutical Company Limited 阻害剤・促進剤の用途
WO2006023893A2 (en) * 2004-08-23 2006-03-02 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for modulating angiogenesis and apoptosis with apelin compositions
US8673848B2 (en) 2012-01-27 2014-03-18 Novartis Ag Synthetic apelin mimetics for the treatment of heart failure
CA2634363A1 (en) 2005-12-20 2007-06-28 Takeda Pharmaceutical Company Limited Novel application of apelin
EP2017355A4 (de) * 2006-04-25 2010-01-06 Univ Kyushu Nat Univ Corp Mit arteriosklerosekrankheit assoziiertes gen und verwendung davon
RU2010114044A (ru) * 2007-09-11 2011-10-20 Мондобайотек Лабораториз Аг (Li) Применение белка полосы 3 (824-829) и/или фактора ингибирования высвобождения меланотропина в качестве терапевтического средства при лечении инфекции pseudomonas aeruginosa
US8946382B2 (en) * 2009-02-27 2015-02-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Apelin peptides and methods of use
GB201012603D0 (en) * 2010-07-27 2010-09-08 Ucb Pharma Sa Protein purification
WO2013050441A1 (en) 2011-10-05 2013-04-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical composition for inhibiting or preventing platelet aggregation
ES2638649T3 (es) 2011-11-28 2017-10-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Composición farmacéutica para su uso en el tratamiento de disfunciones asociadas al envejecimiento
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
US8921307B2 (en) 2012-11-20 2014-12-30 Novartis Ag Synthetic linear apelin mimetics for the treatment of heart failure
SG11201506335YA (en) 2013-03-14 2015-09-29 Regeneron Pharma Apelin fusion proteins and uses thereof
EA201690278A1 (ru) 2013-07-25 2016-06-30 Новартис Аг Циклические полипептиды для лечения сердечной недостаточности
TW201518323A (zh) 2013-07-25 2015-05-16 Novartis Ag 合成ａｐｅｌｉｎ多肽之生物結合物
MX377716B (es) 2013-11-20 2025-03-11 Regeneron Pharma Moduladores de aplnr y usos de estos.
EP3157942B1 (de) 2014-06-23 2020-06-17 Novartis AG Ortsspezifische proteinmodifikationen
US10588980B2 (en) 2014-06-23 2020-03-17 Novartis Ag Fatty acids and their use in conjugation to biomolecules
ES2854400T3 (es) 2014-10-13 2021-09-21 Univ Maryland Fc-ELA--32 y su uso en el tratamiento de afecciones cardiacas
MX2017009534A (es) 2015-01-23 2018-04-10 Novartis Ag Conjugados de acidos grasos y apelina sintetica con mayor vida media.
WO2016151018A1 (en) 2015-03-24 2016-09-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Method and pharmaceutical composition for use in the treatment of diabetes
US11484577B2 (en) 2016-02-15 2022-11-01 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for the treatment of post-operative cognitive dysfunction
EP3228630A1 (de) 2016-04-07 2017-10-11 IMBA-Institut für Molekulare Biotechnologie GmbH Kombination eines apelin-antagonisten und angiogeneseinhibitor zur behandlung von krebs
CN108376608B (zh) * 2018-02-10 2020-11-06 青岛大学 一种磁性纳米粒子及其制备磁性固相载体的用途
CN110655577A (zh) 2018-06-13 2020-01-07 鸿运华宁（杭州）生物医药有限公司 APJ抗体及其与Elabela的融合蛋白质，以及其药物组合物和应用
CN109575117B (zh) * 2018-12-14 2021-09-21 昆明积大制药股份有限公司 [Pyr1]-apelin-13的制备方法
AU2023316015A1 (en) 2022-07-25 2025-02-13 Centre Hospitalier Universitaire De Toulouse Use of apelin for the treatment of lymphedema

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2118372T3 (es) * 1992-11-17 1998-09-16 Icos Corp Nuevos receptores siete transmembrana v28.
CA2232733A1 (en) * 1995-09-20 1997-03-27 Orikkalapat Prem Das Yeast receptor and g-protein fusion protein

Also Published As

Publication number Publication date
EP1040189B1 (de) 2008-01-09
WO1999033976A1 (en) 1999-07-08
KR20010033601A (ko) 2001-04-25
US6492324B1 (en) 2002-12-10
US20090075334A1 (en) 2009-03-19
CA2313246A1 (en) 1999-07-08
DE69838986T2 (de) 2009-01-08
US7410776B2 (en) 2008-08-12
US20030092618A1 (en) 2003-05-15
US7799533B2 (en) 2010-09-21
EP1040189A1 (de) 2000-10-04
CN1283228A (zh) 2001-02-07
ATE383424T1 (de) 2008-01-15
AU1685499A (en) 1999-07-19

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