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DE69833797D1 - Substituierte 2-benzylamino-2-phenyl-acetamidverbindungen - Google Patents

Substituierte 2-benzylamino-2-phenyl-acetamidverbindungen

Info

Publication number
DE69833797D1
DE69833797D1 DE69833797T DE69833797T DE69833797D1 DE 69833797 D1 DE69833797 D1 DE 69833797D1 DE 69833797 T DE69833797 T DE 69833797T DE 69833797 T DE69833797 T DE 69833797T DE 69833797 D1 DE69833797 D1 DE 69833797D1
Authority
DE
Germany
Prior art keywords
benzylamino
phenyl
substituted
acetamide compounds
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69833797T
Other languages
English (en)
Other versions
DE69833797T2 (de
Inventor
Paolo Pevarello
Mario Varasi
Patricia Salvati
Claes Post
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Newron Pharmaceuticals SpA
Original Assignee
Newron Pharmaceuticals SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharmaceuticals SpA filed Critical Newron Pharmaceuticals SpA
Application granted granted Critical
Publication of DE69833797D1 publication Critical patent/DE69833797D1/de
Publication of DE69833797T2 publication Critical patent/DE69833797T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69833797T 1997-12-31 1998-12-12 Substituierte 2-benzylamino-2-phenyl-acetamid-verbindungen Expired - Fee Related DE69833797T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9727521 1997-12-31
GBGB9727521.8A GB9727521D0 (en) 1997-12-31 1997-12-31 Substituted 2-benzylamino-2-phenyl-acetamide compounds
PCT/EP1998/008158 WO1999035123A1 (en) 1997-12-31 1998-12-12 Substituted 2-benzylamino-2-phenyl-acetamide compounds

Publications (2)

Publication Number Publication Date
DE69833797D1 true DE69833797D1 (de) 2006-05-04
DE69833797T2 DE69833797T2 (de) 2006-10-19

Family

ID=10824340

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69833797T Expired - Fee Related DE69833797T2 (de) 1997-12-31 1998-12-12 Substituierte 2-benzylamino-2-phenyl-acetamid-verbindungen

Country Status (23)

Country Link
US (1) US6303819B1 (de)
EP (1) EP1044186B9 (de)
JP (1) JP3839665B2 (de)
KR (1) KR100629628B1 (de)
AT (1) ATE319680T1 (de)
BG (1) BG64700B1 (de)
CA (1) CA2316082C (de)
CZ (1) CZ296722B6 (de)
DE (1) DE69833797T2 (de)
EA (1) EA003097B1 (de)
ES (1) ES2256976T3 (de)
GB (1) GB9727521D0 (de)
HK (1) HK1028021A1 (de)
HR (1) HRP20000508B9 (de)
HU (1) HUP0100184A3 (de)
ID (1) ID26622A (de)
IL (1) IL136735A0 (de)
NO (1) NO327259B1 (de)
NZ (1) NZ505441A (de)
PL (1) PL194745B1 (de)
PT (1) PT1044186E (de)
TR (1) TR200001950T2 (de)
WO (1) WO1999035123A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
MXPA03004644A (es) * 2000-11-27 2003-09-05 Pharmacia Italia Spa Derivados de fenilacetamdia-pirazol y su uso como agentes antitumorales.
ATE317280T1 (de) 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
US6667327B2 (en) 2002-02-04 2003-12-23 Hoffmann-La Roche Inc. Pyridine amido derivatives
EP1438956A1 (de) * 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind
WO2004087125A1 (en) * 2003-04-02 2004-10-14 Ionix Pharmaceuticals Limited Amino acid derivatives as inhibitors of mammalian sodium channels
EP1524267A1 (de) * 2003-10-15 2005-04-20 Newron Pharmaceuticals S.p.A. Substituierte Benzylaminoalkylen-Heterozyklen
EP1680127B1 (de) 2003-10-23 2008-10-15 F. Hoffmann-La Roche Ag Benzazepin-derivate als mao-b-hemmer
EP1533302A1 (de) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. Histidinderivate
EP1533298A1 (de) * 2003-11-21 2005-05-25 Newron Pharmaceuticals S.p.A. 3-aminopyrrolidonederivate
EP1535908A1 (de) * 2003-11-24 2005-06-01 Newron Pharmaceuticals S.p.A. N-Acyl-N'-Beznylalyklendiamin Derivate
EP1588704A1 (de) 2004-04-22 2005-10-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidderivate zur Behandlung des Restless-Leg-Syndroms und der Suchterkrankungen
RS51411B (en) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. USE (R) - (HALOBENZYLOXY) BENZYLAMINO-PROPANAMIDE AS SELECTIVE MODULATORS OF SODIUM AND / OR CALCIUM CHANNELS
HUE028329T2 (en) * 2005-12-22 2016-12-28 Newron Pharm Spa 2-Phenylethylamino derivatives acting as calcium and / or sodium channel modulators
EP1870097A1 (de) 2006-06-15 2007-12-26 Newron Pharmaceuticals S.p.A. Alpha-aminoamidederivate zur Behandlung von kognitiven Störungen
CA2679039A1 (en) * 2007-03-05 2008-09-12 F. Hoffmann-La Roche Ag Aminoamides as orexin antagonists
US11111208B2 (en) * 2019-06-17 2021-09-07 RK Pharma Solutions LLC Process for the preparation of safinamide mesylate intermediate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541204A (en) * 1994-12-02 1996-07-30 Bristol-Myers Squibb Company Aryloxypropanolamine β 3 adrenergic agonists
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
US5688830A (en) 1996-01-25 1997-11-18 Syntex (U.S.A.) Inc. Treatment of neuropathic pain

Also Published As

Publication number Publication date
HRP20000508B1 (en) 2007-02-28
CA2316082C (en) 2006-02-07
ID26622A (id) 2001-01-25
PL194745B1 (pl) 2007-06-29
IL136735A0 (en) 2001-06-14
GB9727521D0 (en) 1998-02-25
EP1044186B1 (de) 2006-03-08
HRP20000508A2 (en) 2001-02-28
PL341514A1 (en) 2001-04-23
WO1999035123A1 (en) 1999-07-15
HRP20000508B9 (en) 2008-05-31
EA003097B1 (ru) 2002-12-26
EP1044186B9 (de) 2006-06-21
BG104569A (en) 2001-02-28
DE69833797T2 (de) 2006-10-19
KR100629628B1 (ko) 2006-09-29
BG64700B1 (bg) 2005-12-30
KR20010033779A (ko) 2001-04-25
ATE319680T1 (de) 2006-03-15
NO20003398D0 (no) 2000-06-29
HUP0100184A2 (hu) 2001-07-30
EP1044186A1 (de) 2000-10-18
JP3839665B2 (ja) 2006-11-01
NO20003398L (no) 2000-08-02
PT1044186E (pt) 2006-07-31
TR200001950T2 (tr) 2000-11-21
NO327259B1 (no) 2009-05-25
JP2002500214A (ja) 2002-01-08
NZ505441A (en) 2001-12-21
CA2316082A1 (en) 1999-07-15
HUP0100184A3 (en) 2002-11-28
US6303819B1 (en) 2001-10-16
HK1028021A1 (en) 2001-02-02
ES2256976T3 (es) 2006-07-16
CZ296722B6 (cs) 2006-05-17
EA200000728A1 (ru) 2001-02-26
CZ20002496A3 (cs) 2000-12-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee