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DE69831594D1 - Intakte oder zerstörte insektenzellen als antigenadjuvant - Google Patents

Intakte oder zerstörte insektenzellen als antigenadjuvant

Info

Publication number
DE69831594D1
DE69831594D1 DE69831594T DE69831594T DE69831594D1 DE 69831594 D1 DE69831594 D1 DE 69831594D1 DE 69831594 T DE69831594 T DE 69831594T DE 69831594 T DE69831594 T DE 69831594T DE 69831594 D1 DE69831594 D1 DE 69831594D1
Authority
DE
Germany
Prior art keywords
insect cells
adjuvant
antigen
antigenadjuvant
intact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831594T
Other languages
English (en)
Other versions
DE69831594T2 (de
Inventor
Eugene Smith
James Debartolomeis
Igorevitch Voznesenski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merial LLC
Original Assignee
Protein Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25510359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69831594(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Protein Sciences Corp filed Critical Protein Sciences Corp
Publication of DE69831594D1 publication Critical patent/DE69831594D1/de
Application granted granted Critical
Publication of DE69831594T2 publication Critical patent/DE69831594T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69831594T 1997-11-07 1998-11-04 Intakte oder zerstörte insektenzellen als antigenadjuvant Expired - Lifetime DE69831594T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/965,698 US6224882B1 (en) 1997-11-07 1997-11-07 Insect cells or fractions as adjuvant for antigens
US965698 1997-11-07
PCT/US1998/023472 WO1999024049A1 (en) 1997-11-07 1998-11-04 Insect cells or fractions as adjuvant for antigens

Publications (2)

Publication Number Publication Date
DE69831594D1 true DE69831594D1 (de) 2006-01-26
DE69831594T2 DE69831594T2 (de) 2006-07-06

Family

ID=25510359

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831594T Expired - Lifetime DE69831594T2 (de) 1997-11-07 1998-11-04 Intakte oder zerstörte insektenzellen als antigenadjuvant

Country Status (11)

Country Link
US (1) US6224882B1 (de)
EP (2) EP1033995B1 (de)
AT (1) ATE304369T1 (de)
AU (1) AU1379599A (de)
CA (1) CA2309003C (de)
DE (1) DE69831594T2 (de)
DK (1) DK1033995T3 (de)
ES (1) ES2248921T3 (de)
NZ (1) NZ504424A (de)
PT (1) PT1033995E (de)
WO (1) WO1999024049A1 (de)

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US20060228326A1 (en) * 2002-10-22 2006-10-12 Fidler Isaiah J Active specific immunotherapy of cancer metastasis
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US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
WO2005021713A2 (en) 2003-06-20 2005-03-10 Protein Sciences Corporation Vectors expressing sars immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using
US8992939B2 (en) 2003-07-11 2015-03-31 Novavax, Inc. Highly efficient influenza matrix (M1) proteins
US8506967B2 (en) 2003-07-11 2013-08-13 Novavax, Inc. Functional influenza virus like particles (VLPs)
US8080255B2 (en) * 2003-07-11 2011-12-20 Novavax Inc. Functional influenza virus like particles (VLPs)
US8592197B2 (en) 2003-07-11 2013-11-26 Novavax, Inc. Functional influenza virus-like particles (VLPs)
MXPA06005424A (es) 2003-11-13 2007-01-25 Univ Georgia Res Found Metodos para caracterizar virus de enfermedad bursal infecciosa.
JP2007525217A (ja) 2004-02-19 2007-09-06 ザ ガバナーズ オブ ザ ユニバーシティー オブ アルバータ レプチンプロモーター多型及びその使用
PT1881845E (pt) 2005-04-25 2010-05-31 Merial Ltd Vacinas de vírus nipah
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
CA2621666A1 (en) * 2005-09-09 2007-03-15 Universitaet Zuerich Antigens for vaccination against and detection of mycoplasma suis
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
EP1951751B1 (de) 2005-11-14 2017-11-01 Merial, Inc. Gentherapie bei nierenversagen
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
WO2008009115A1 (en) * 2006-07-18 2008-01-24 Ottawa Health Research Institute Disparate suicide carrier cells for tumor targeting of promiscuous oncolytic viruses
EP3168307B1 (de) 2008-11-28 2020-07-15 Boehringer Ingelheim Animal Health USA Inc. Rekombinanter impfstoff gegen vogelgrippe und verwendungen davon
CN103585643A (zh) 2009-04-03 2014-02-19 梅里亚有限公司 运载新城疫病毒的禽疫苗
JP5913316B2 (ja) 2010-08-31 2016-04-27 メリアル リミテッド ニューカッスル病ウイルスをベクターとするヘルペスウイルスワクチン
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
EP2694678A2 (de) 2011-04-04 2014-02-12 Netherland Cancer Institute Verfahren und zusammensetzungen zur vorhersage der resistenz gegenüber einer antikrebsbehandlung
US20140296248A1 (en) 2011-04-04 2014-10-02 Stichting het Nederlands Kanker Instiuut-Antoni van Leeuwenhoek ziekenhuis Methods and compositions for predicting resistance to anticancer treatment
AU2012245395A1 (en) 2011-04-20 2013-11-14 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
JP6407714B2 (ja) 2011-04-25 2018-10-17 アドヴァンスド バイオサイエンス ラボラトリーズ インコーポレイテッド 短縮型hivエンベロープタンパク質(env)、前記に関連する方法及び組成物
WO2012166493A1 (en) 2011-06-01 2012-12-06 Merial Limited Needle-free administration of prrsv vaccines
ES2626297T3 (es) 2011-08-12 2017-07-24 Merial, Inc. Preservación asistida por vacío de productos biológicos, en particular de vacunas
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
WO2014164697A1 (en) 2013-03-12 2014-10-09 Merial Limited Reverse genetics schmallenberg virus vaccine compositions, and methods of use thereof
PL2994162T3 (pl) 2013-05-08 2021-10-18 Pharmgate Biologics Inc. Szczepionka przeciwko pcv2 i mykoplazmie
WO2016073410A1 (en) 2014-11-03 2016-05-12 Merial, Inc. Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
CA2990643C (en) 2015-06-23 2023-10-17 Merial, Inc. Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
CN108135997A (zh) 2015-08-20 2018-06-08 梅里亚股份有限公司 Fcv重组疫苗及其用途

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US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5505941A (en) 1981-12-24 1996-04-09 Health Research, Inc. Recombinant avipox virus and method to induce an immune response
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US4722848A (en) 1982-12-08 1988-02-02 Health Research, Incorporated Method for immunizing animals with synthetically modified vaccinia virus
US5338683A (en) 1981-12-24 1994-08-16 Health Research Incorporated Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins
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IE872748L (en) 1986-10-16 1988-04-16 Arjomari Europ Polypeptides derived from the evvelope gene of human¹immunodeficiency virus in recombinant baculovirus infected¹insect cells
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WO1991009870A1 (de) 1989-12-22 1991-07-11 Mikrogen Molekularbiologische Entwicklungs-Gmbh Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff
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EP0650527B1 (de) 1991-10-22 2003-03-12 Symbicom Ab Verbesserungen der diagnose und der prophylaxe von borrelia burgdorferi
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JP4922923B2 (ja) 2004-04-13 2012-04-25 ドナルドソン カンパニー,インコーポレイティド 液体ろ過用のフィルタ・カートリッジ
CN116285747A (zh) 2014-03-21 2023-06-23 艾利丹尼森公司 无面标签以及相关系统和方法

Also Published As

Publication number Publication date
PT1033995E (pt) 2005-11-30
WO1999024049A1 (en) 1999-05-20
CA2309003A1 (en) 1999-05-20
US6224882B1 (en) 2001-05-01
NZ504424A (en) 2001-09-28
ATE304369T1 (de) 2005-09-15
WO1999024049A9 (en) 1999-08-12
EP1611897A2 (de) 2006-01-04
DK1033995T3 (da) 2006-01-30
EP1033995A4 (de) 2001-01-10
DE69831594T2 (de) 2006-07-06
AU1379599A (en) 1999-05-31
EP1033995B1 (de) 2005-09-14
EP1611897A3 (de) 2007-08-15
ES2248921T3 (es) 2006-03-16
EP1033995A1 (de) 2000-09-13
CA2309003C (en) 2012-10-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERIAL LTD., HARLOW, ESSEX, GB

8327 Change in the person/name/address of the patent owner

Owner name: MERIAL LTD., DULUTH, GA., US

8310 Action for declaration of annulment
8313 Request for invalidation rejected/withdrawn