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DE69829408T8 - Herstellungsverfahren einer virusfreien faktor viii-lösung durch filtration - Google Patents

Herstellungsverfahren einer virusfreien faktor viii-lösung durch filtration Download PDF

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Publication number
DE69829408T8
DE69829408T8 DE69829408T DE69829408T DE69829408T8 DE 69829408 T8 DE69829408 T8 DE 69829408T8 DE 69829408 T DE69829408 T DE 69829408T DE 69829408 T DE69829408 T DE 69829408T DE 69829408 T8 DE69829408 T8 DE 69829408T8
Authority
DE
Germany
Prior art keywords
factor viii
preparing
virus
filtration
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE69829408T
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English (en)
Other versions
DE69829408T3 (de
DE69829408T2 (de
DE69829408D1 (de
Inventor
Abdessatar Chtourou (Sami)
Michel Nogre
Pierre Porte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB SA
Original Assignee
LFB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9514631&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69829408(T8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LFB SA filed Critical LFB SA
Application granted granted Critical
Publication of DE69829408D1 publication Critical patent/DE69829408D1/de
Publication of DE69829408T2 publication Critical patent/DE69829408T2/de
Publication of DE69829408T8 publication Critical patent/DE69829408T8/de
Publication of DE69829408T3 publication Critical patent/DE69829408T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69829408.4T 1997-12-15 1998-12-14 Herstellungsverfahren einer virusfreien faktor viii-lösung durch filtration Expired - Lifetime DE69829408T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9715888A FR2772381B1 (fr) 1997-12-15 1997-12-15 Procede de preparation par filtration d'une solution de facteur viii securisee viralement
FR9715888 1997-12-15
PCT/FR1998/002715 WO1999031138A1 (fr) 1997-12-15 1998-12-14 Procede de preparation par filtration d'une solution de facteur viii securisee viralement
EP98959975.8A EP1037923B2 (de) 1997-12-15 1998-12-14 Herstellungsverfahren einer virusfreien faktor viii-lösung durch filtration

Publications (4)

Publication Number Publication Date
DE69829408D1 DE69829408D1 (de) 2005-04-21
DE69829408T2 DE69829408T2 (de) 2006-04-13
DE69829408T8 true DE69829408T8 (de) 2006-08-10
DE69829408T3 DE69829408T3 (de) 2015-11-12

Family

ID=9514631

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829408.4T Expired - Lifetime DE69829408T3 (de) 1997-12-15 1998-12-14 Herstellungsverfahren einer virusfreien faktor viii-lösung durch filtration

Country Status (11)

Country Link
US (1) US6967239B1 (de)
EP (1) EP1037923B2 (de)
JP (1) JP4312381B2 (de)
AT (1) ATE291034T1 (de)
AU (1) AU752271B2 (de)
CA (1) CA2314610C (de)
DE (1) DE69829408T3 (de)
ES (1) ES2237854T5 (de)
FR (1) FR2772381B1 (de)
PT (1) PT1037923E (de)
WO (1) WO1999031138A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU784808B2 (en) * 2001-04-02 2006-06-29 Kedrion Melville Inc. Prion and viral clearance process
DE10211632A1 (de) * 2002-03-15 2003-10-09 Aventis Behring Gmbh Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration
ES2214967B1 (es) * 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
FR2920429B1 (fr) * 2007-08-30 2012-10-05 Lfb Biotechnologies Procede de purification du facteur viii et du facteur von willebrand
MX2010007150A (es) 2007-12-28 2010-09-03 Baxter Int Formulaciones del factor de von-willebrand recombinante.
ES2377038T3 (es) 2007-12-28 2012-03-21 Baxter International Inc. Filtración de proteínas a contra-presión
ES2298096B1 (es) * 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
TWI469992B (zh) * 2008-08-28 2015-01-21 Baxter Int 濃縮剪切靈敏生物聚合物的方法
AU2011343813B2 (en) 2010-12-15 2015-05-21 Takeda Pharmaceutical Company Limited Eluate collection using conductivity gradient
US20140154233A1 (en) 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
KR20200038309A (ko) * 2017-08-23 2020-04-10 체에스엘 베링 게엠베하 폰 빌레브란트 인자의 바이러스 여과 방법
CA3091348A1 (en) * 2018-02-19 2019-08-22 Bayer Healthcare Llc Modified filter membrane and method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673733A (en) * 1985-04-11 1987-06-16 Sudhish Chandra Treatment of biological and pharmaceutical products adsorbed on a solid phase with virus and pyrogen inactivating agents
US4758657A (en) † 1985-07-11 1988-07-19 Armour Pharmaceutical Company Method of purifying Factor VIII:C
FR2644064B1 (fr) * 1989-02-17 1994-05-27 Aquitaine Dev Transf Sanguine Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
IT1248723B (it) * 1990-06-12 1995-01-26 Scalvo S P A Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo
FR2681867B1 (fr) * 1991-09-26 1993-12-31 Pasteur Merieux Serums Vaccins Procede de purification du facteur viii et preparations obtenues.
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
DE4435392B4 (de) 1994-10-04 2008-02-07 Immuno Ag Verfahren zur Trennung von vWF in hochmolekularen vWF und niedermolekularen vWF
US5677162A (en) * 1995-05-01 1997-10-14 New York Blood Center, Inc. Method for activating prothrombin to thrombin
EP0860444A1 (de) † 1997-02-24 1998-08-26 Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) Methode zur Entfernung von Viren aus Proteinlösungen

Also Published As

Publication number Publication date
FR2772381A1 (fr) 1999-06-18
JP2002508396A (ja) 2002-03-19
EP1037923B2 (de) 2015-09-09
ES2237854T3 (es) 2005-08-01
DE69829408T3 (de) 2015-11-12
EP1037923B9 (de) 2006-08-23
ATE291034T1 (de) 2005-04-15
EP1037923A1 (de) 2000-09-27
ES2237854T5 (es) 2015-10-05
EP1037923B1 (de) 2005-03-16
FR2772381B1 (fr) 2001-06-08
CA2314610A1 (fr) 1999-06-24
US6967239B1 (en) 2005-11-22
DE69829408T2 (de) 2006-04-13
WO1999031138A1 (fr) 1999-06-24
JP4312381B2 (ja) 2009-08-12
PT1037923E (pt) 2005-06-30
CA2314610C (fr) 2012-06-19
AU752271B2 (en) 2002-09-12
AU1568199A (en) 1999-07-05
DE69829408D1 (de) 2005-04-21

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8363 Opposition against the patent