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DE69829181D1 - Verbesserte trennsäulen und verfahren zur herstellung der verbesserten trennsäulen - Google Patents

Verbesserte trennsäulen und verfahren zur herstellung der verbesserten trennsäulen

Info

Publication number
DE69829181D1
DE69829181D1 DE69829181T DE69829181T DE69829181D1 DE 69829181 D1 DE69829181 D1 DE 69829181D1 DE 69829181 T DE69829181 T DE 69829181T DE 69829181 T DE69829181 T DE 69829181T DE 69829181 D1 DE69829181 D1 DE 69829181D1
Authority
DE
Germany
Prior art keywords
trense
columns
improved
producing
trense columns
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69829181T
Other languages
English (en)
Other versions
DE69829181T2 (de
Inventor
E Regnier
Bing He
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of DE69829181D1 publication Critical patent/DE69829181D1/de
Application granted granted Critical
Publication of DE69829181T2 publication Critical patent/DE69829181T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44791—Microapparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6043—Construction of the column joining multiple columns in parallel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00—Agitating
    • Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE69829181T 1997-05-27 1998-05-18 Verbesserte trennsäulen und verfahren zur herstellung der verbesserten trennsäulen Expired - Fee Related DE69829181T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/863,543 US6156273A (en) 1997-05-27 1997-05-27 Separation columns and methods for manufacturing the improved separation columns
US863543 1997-05-27
PCT/US1998/009960 WO1998054568A1 (en) 1997-05-27 1998-05-18 Improved separation columns and methods for manufacturing the improved separation columns

Publications (2)

Publication Number Publication Date
DE69829181D1 true DE69829181D1 (de) 2005-04-07
DE69829181T2 DE69829181T2 (de) 2005-12-29

Family

ID=25341272

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829181T Expired - Fee Related DE69829181T2 (de) 1997-05-27 1998-05-18 Verbesserte trennsäulen und verfahren zur herstellung der verbesserten trennsäulen

Country Status (4)

Country Link
US (2) US6156273A (de)
EP (1) EP0985146B1 (de)
DE (1) DE69829181T2 (de)
WO (1) WO1998054568A1 (de)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6156273A (en) * 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns
WO1999000657A1 (en) * 1997-06-26 1999-01-07 Perseptive Biosystems, Inc. High density sample holder for analysis of biological samples
US6368871B1 (en) * 1997-08-13 2002-04-09 Cepheid Non-planar microstructures for manipulation of fluid samples
US5842787A (en) * 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
AU758407B2 (en) 1997-12-24 2003-03-20 Cepheid Integrated fluid manipulation cartridge
US6866786B2 (en) * 1998-04-03 2005-03-15 Symyx Technologies, Inc. Rapid characterization of polymers
US6540896B1 (en) * 1998-08-05 2003-04-01 Caliper Technologies Corp. Open-Field serial to parallel converter
EP1112498B1 (de) * 1998-08-20 2008-03-05 Siemens Aktiengesellschaft Trennsäulen-einheit für einen gaschromatograph und verfahren zu ihrer herstellung
JP4274399B2 (ja) * 1998-09-17 2009-06-03 アドヴィオン バイオシステムズ インコーポレイテッド 一体化モノリシックマイクロ加工したエレクトロスプレーと液体クロマトグラフィーのシステムおよび方法
US6431476B1 (en) 1999-12-21 2002-08-13 Cepheid Apparatus and method for rapid ultrasonic disruption of cells or viruses
US7914994B2 (en) 1998-12-24 2011-03-29 Cepheid Method for separating an analyte from a sample
US6855258B2 (en) * 1999-04-02 2005-02-15 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimensional liquid chromatography with parallel second-dimension sampling
US6270641B1 (en) 1999-04-26 2001-08-07 Sandia Corporation Method and apparatus for reducing sample dispersion in turns and junctions of microchannel systems
US9073053B2 (en) 1999-05-28 2015-07-07 Cepheid Apparatus and method for cell disruption
US20040200909A1 (en) * 1999-05-28 2004-10-14 Cepheid Apparatus and method for cell disruption
US8815521B2 (en) 2000-05-30 2014-08-26 Cepheid Apparatus and method for cell disruption
CA2374423C (en) 1999-05-28 2013-04-09 Cepheid Apparatus and method for analyzing a liquid sample
US6635163B1 (en) * 1999-06-01 2003-10-21 Cornell Research Foundation, Inc. Entropic trapping and sieving of molecules
US6664104B2 (en) 1999-06-25 2003-12-16 Cepheid Device incorporating a microfluidic chip for separating analyte from a sample
ES2316376T3 (es) 1999-08-06 2009-04-16 Chempaq A/S Aparato de caracterizacion de particulas.
US6906797B1 (en) * 1999-09-13 2005-06-14 Aclara Biosciences, Inc. Side light activated microfluid channels
JP2003527972A (ja) * 1999-10-04 2003-09-24 ナノストリーム・インコーポレイテッド 挟まれたステンシルを含むモジュラー型マイクロ流体デバイス
US6824664B1 (en) * 1999-11-04 2004-11-30 Princeton University Electrode-less dielectrophorises for polarizable particles
EP1248949B1 (de) * 2000-01-18 2013-05-22 Advion, Inc. Elektrosprayvorrichtung mit array von trennsäulen sowie verfahren zur trennung von fluidproben
US6451264B1 (en) * 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
US6685813B2 (en) * 2000-02-11 2004-02-03 Aclara Biosciences, Inc. Tandem isotachophoresis/zone electrophoresis method and system
AU2001234997B2 (en) 2000-02-11 2006-07-27 Monogram Biosciences, Inc. Microfluid device with sample injector and method of use
WO2001063273A2 (en) * 2000-02-22 2001-08-30 California Institute Of Technology Development of a gel-free molecular sieve based on self-assembled nano-arrays
JP2001281233A (ja) * 2000-03-28 2001-10-10 Inst Of Physical & Chemical Res 水性分配用マイクロチップおよびそれを用いた水性分配方法
DE10055374B4 (de) * 2000-11-08 2006-03-02 Bartels Mikrotechnik Gmbh Verteilerplatte für Flüssigkeiten und Gase
US6881317B2 (en) * 2000-12-18 2005-04-19 The Trustees Of Princeton University Fractionation of macro-molecules using asymmetric pulsed field electrophoresis
AUPR244801A0 (en) * 2001-01-10 2001-02-01 Silverbrook Research Pty Ltd A method and apparatus (WSM01)
US6913697B2 (en) 2001-02-14 2005-07-05 Science & Technology Corporation @ Unm Nanostructured separation and analysis devices for biological membranes
US7316769B2 (en) * 2001-03-19 2008-01-08 Cornell Research Foundation, Inc. Length-dependent recoil separation of long molecules
RU2288028C2 (ru) * 2001-05-17 2006-11-27 Амальгэмэйтед Резерч, Инк. Устройство для смешивания по меньшей мере двух текучих сред
US6919046B2 (en) * 2001-06-07 2005-07-19 Nanostream, Inc. Microfluidic analytical devices and methods
US7014747B2 (en) * 2001-06-20 2006-03-21 Sandia Corporation Dielectrophoretic systems without embedded electrodes
WO2003013703A1 (en) * 2001-08-03 2003-02-20 Aclara Biosciences, Inc. Straightflow system
WO2003021251A1 (en) * 2001-08-28 2003-03-13 Symyx Technologies, Inc. Methods for characterization of polymers using multi-dimentional liquid chromatography
US6755949B1 (en) 2001-10-09 2004-06-29 Roche Diagnostics Corporation Biosensor
US7597791B2 (en) * 2001-10-19 2009-10-06 The Trustees Of Princeton University Method and apparatus for generating electric fields and flow distributions for rapidly separating molecules
US20030098661A1 (en) * 2001-11-29 2003-05-29 Ken Stewart-Smith Control system for vehicle seats
EP1319948A3 (de) * 2001-12-12 2004-11-24 Jim Dong Nanogefertigte Chromatographiekolonne
US6845787B2 (en) * 2002-02-23 2005-01-25 Nanostream, Inc. Microfluidic multi-splitter
FR2839660B1 (fr) * 2002-05-17 2005-01-21 Commissariat Energie Atomique Microreacteur,son procede de preparation,et procede pour realiser une reaction biochimique ou biologique
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
AU2003232169B8 (en) 2002-06-11 2008-05-08 Koninklijke Philips Electronics N.V. A disposable cartridge for characterizing particles suspended in a liquid
WO2004008132A1 (ja) * 2002-07-11 2004-01-22 Mitsubishi Denki Kabushiki Kaisha 生体分子分離セル及びその製造方法並びにｄｎａ分取装置
US7517440B2 (en) 2002-07-17 2009-04-14 Eksigent Technologies Llc Electrokinetic delivery systems, devices and methods
US7364647B2 (en) * 2002-07-17 2008-04-29 Eksigent Technologies Llc Laminated flow device
US7235164B2 (en) 2002-10-18 2007-06-26 Eksigent Technologies, Llc Electrokinetic pump having capacitive electrodes
ATE531257T1 (de) 2002-09-27 2011-11-15 Gen Hospital Corp Mikrofluidische vorrichtung zur zelltrennung und verwendungen davon
AU2003287449A1 (en) * 2002-10-31 2004-05-25 Nanostream, Inc. Parallel detection chromatography systems
GB0300820D0 (en) * 2003-01-14 2003-02-12 Diagnoswiss Sa Membrane-microchannel strip
DE10303107B3 (de) * 2003-01-27 2004-09-16 Sls Micro Technology Gmbh Trennsäule, insbesondere für einen miniaturisierten Gaschromatographen
US20050095602A1 (en) * 2003-11-04 2005-05-05 West Jason A. Microfluidic integrated microarrays for biological detection
JP2005257337A (ja) * 2004-03-09 2005-09-22 Brother Ind Ltd 検査対象受体、検査装置、及び検査方法
SE0400662D0 (sv) 2004-03-24 2004-03-24 Aamic Ab Assay device and method
US7559356B2 (en) * 2004-04-19 2009-07-14 Eksident Technologies, Inc. Electrokinetic pump driven heat transfer system
SE527036C2 (sv) * 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
US7491363B2 (en) * 2004-07-15 2009-02-17 Applied Biosystems, Llc. Fluid processing device
CA2855108A1 (en) 2005-02-10 2006-08-17 Koninklijke Philips Electronics N.V. Dual sample cartridge and method for characterizing particles in liquid
EP1891413B1 (de) 2005-02-10 2018-01-24 Koninklijke Philips N.V. Doppelprobenkassette und verfahren zur charakterisierung von partikeln in flüssigkeit
EP1875224B1 (de) * 2005-03-17 2009-04-29 Vrije Universiteit Brussel Verfahren zur herstellung monolithischer trenn- und reaktionsmedien in einem trenn- oder reaktionskanal
WO2006097302A1 (en) * 2005-03-17 2006-09-21 Vrije Universiteit Brussel Method for manufacturing packed bed column and packed bed column obtained therewith
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
JP2008538282A (ja) * 2005-04-05 2008-10-23 セルポイント ダイアグノスティクス， インコーポレイテッド 装置および循環腫瘍細胞および他の粒子の濃縮および変更のための方法
US20070009909A1 (en) * 2005-06-30 2007-01-11 Lopez Herman A Sorting of carbon nanotubes through arrays
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US20070059716A1 (en) * 2005-09-15 2007-03-15 Ulysses Balis Methods for detecting fetal abnormality
US8794929B2 (en) 2005-11-23 2014-08-05 Eksigent Technologies Llc Electrokinetic pump designs and drug delivery systems
US20090298139A1 (en) * 2006-02-28 2009-12-03 Jin Zou Method for Polymer Synthesis Using Microfluidic Enzymatic Cascade
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
EP2589668A1 (de) 2006-06-14 2013-05-08 Verinata Health, Inc Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten
US20080070792A1 (en) 2006-06-14 2008-03-20 Roland Stoughton Use of highly parallel snp genotyping for fetal diagnosis
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
JP5173165B2 (ja) * 2006-08-14 2013-03-27 東京エレクトロン株式会社 クロマトグラフィ用のカラム及びその製造方法
US8017015B2 (en) 2006-10-20 2011-09-13 Quest Diagnostics Investments Incorporated Monolithic column chromatography
US8037927B2 (en) * 2006-11-16 2011-10-18 CUI Global, Inc. Cooling device for an electronic component
US7867592B2 (en) 2007-01-30 2011-01-11 Eksigent Technologies, Inc. Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces
DK3550298T3 (da) 2007-05-23 2021-02-08 Pharmafluidics Nv Fremgangsmåde og indretning til fordeling af prøve og bærervæske over en mikrofremstillet separationskanal
WO2008142160A1 (en) * 2007-05-23 2008-11-27 Vrije Universiteit Brussel Device for the distribution of sample and carrier liquid across a micro-fabricated separation channel
WO2009076134A1 (en) 2007-12-11 2009-06-18 Eksigent Technologies, Llc Electrokinetic pump with fixed stroke volume
GB2470854A (en) * 2008-04-23 2010-12-08 Agilent Technologies Inc Microstructured separation element with a porous surface coating
AU2009293354B2 (en) 2008-09-20 2015-01-29 The Board Of Trustees Of The Leland Stanford Junior University Noninvasive diagnosis of fetal aneuploidy by sequencing
US8085578B2 (en) * 2009-03-13 2011-12-27 Paul Scherrer Institut Method and system for coding and read out of information in a microscopic cluster comprising coupled functional islands
JP5816613B2 (ja) * 2009-04-23 2015-11-18 ダブリン シティ ユニバーシティ 凝固をモニタするための側方流動分析装置及びその方法
US11143636B2 (en) 2009-05-29 2021-10-12 Cytiva Sweden Ab Fluid distributor unit
US20110065101A1 (en) 2009-06-04 2011-03-17 Lockheed Martin Corporation Multiple-sample microfluidic chip for DNA analysis
US20120227470A1 (en) * 2009-06-26 2012-09-13 Waters Technologies Corporation Chromatography Apparatus Having An Integrated Core
EP2269737B1 (de) * 2009-07-02 2017-09-13 Amic AB Testvorrichtung mit seriellen Reaktionszonen
DE102009052234A1 (de) 2009-11-06 2011-05-12 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Auf Waferebene herstellbarer Chip für Flüssigchromatographie sowie Verfahren für seine Herstellung
KR101061225B1 (ko) 2009-11-12 2011-08-31 포항공과대학교 산학협력단 유체 수송관 네크워크의 제조 방법 및 이를 이용한 유체 수송관 네트워크
KR101155085B1 (ko) * 2009-12-18 2012-06-11 광주과학기술원 세포 용해 장치 및 그 제조 방법
US8511889B2 (en) * 2010-02-08 2013-08-20 Agilent Technologies, Inc. Flow distribution mixer
JP2011174856A (ja) * 2010-02-25 2011-09-08 Tokyo Electron Ltd クロマトグラフィー用カラム、その製造方法、および分析装置
US8415086B2 (en) * 2010-04-15 2013-04-09 Paul Scherrer Institut Method of studying chirality controlled artificial kagome spin ice building blocks
WO2012002249A1 (ja) * 2010-06-28 2012-01-05 Ｄｉｃ 株式会社 マイクロミキサー
JP5530522B2 (ja) * 2010-07-26 2014-06-25 浜松ホトニクス株式会社 半導体デバイスの製造方法
US8961764B2 (en) 2010-10-15 2015-02-24 Lockheed Martin Corporation Micro fluidic optic design
BR112013025837A2 (pt) 2011-04-06 2016-12-20 Ortho Clinical Diagnostics Inc dispositivo de ensaio que tem projeções em formato de losango
CA2834708A1 (en) 2011-05-05 2012-11-08 Eksigent Technologies, Llc Gel coupling for electrokinetic delivery systems
US10773863B2 (en) 2011-06-22 2020-09-15 Sartorius Stedim North America Inc. Vessel closures and methods for using and manufacturing same
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
KR101605518B1 (ko) * 2014-10-24 2016-03-22 주식회사 센플러스 미소입자의 자기 배열을 위한 장치 및 방법
GB201511463D0 (en) 2015-06-30 2015-08-12 Ge Healthcare Bio Sciences Ab Improvements in and relating to fluid path networks
CN106152846B (zh) * 2016-07-09 2017-04-05 南京艾科美热能科技有限公司 一种自循环气液两相流相变换热器
WO2018037244A1 (en) * 2016-08-26 2018-03-01 Puridify Ltd. Chromatography system
US10603647B2 (en) * 2016-12-01 2020-03-31 Imagine Tf, Llc Microstructure flow mixing devices
US11577953B2 (en) 2017-11-14 2023-02-14 Sartorius Stedim North America, Inc. System for simultaneous distribution of fluid to multiple vessels and method of using the same
US11319201B2 (en) 2019-07-23 2022-05-03 Sartorius Stedim North America Inc. System for simultaneous filling of multiple containers
US11691866B2 (en) 2017-11-14 2023-07-04 Sartorius Stedim North America Inc. System for simultaneous distribution of fluid to multiple vessels and method of using the same
US12252391B2 (en) 2017-11-14 2025-03-18 Sartorius Stedim North America Inc. System for simultaneous distribution of fluid to multiple vessels and method of using the same
US11027108B2 (en) 2017-11-14 2021-06-08 Sartorius Stedim North America Inc. Fluid transfer assembly with a junction having multiple fluid pathways
TWI738581B (zh) * 2020-12-03 2021-09-01 國立臺灣師範大學 平板式氧化鋁氣相層析管柱及其製作方法
BE1028976B1 (nl) * 2020-12-30 2022-08-01 Pharmafluidics N V Pilaarstructuren
US12239127B2 (en) 2021-07-28 2025-03-04 Sartorius Stedim North America Inc. Thermal capacitors, systems, and methods for rapid freezing or heating of biological materials
WO2024240954A1 (en) * 2023-05-25 2024-11-28 Pharmafluidics Nv Void span reducing structures in a chemical reactor

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640813A (en) * 1969-06-09 1972-02-08 Samuel T Nerenberg Adapter for a macromolecule separation device
JPS6042653A (ja) * 1983-08-17 1985-03-06 Shionogi & Co Ltd クロマトグラフィ−・プレ−ト
US5116495A (en) * 1987-09-11 1992-05-26 Ottosensors Corporation Capillary chromatography device
US4980057A (en) * 1989-10-03 1990-12-25 General Electric Company Apparatus for mass spectrometric analysis of liquid chromatographic fractions
GB2244135B (en) * 1990-05-04 1994-07-13 Gen Electric Co Plc Sensor devices
US5632957A (en) * 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
EP0637998B2 (de) * 1992-05-01 2006-04-12 Trustees Of The University Of Pennsylvania Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen
US5304487A (en) * 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5296375A (en) * 1992-05-01 1994-03-22 Trustees Of The University Of Pennsylvania Mesoscale sperm handling devices
US5427663A (en) * 1993-06-08 1995-06-27 British Technology Group Usa Inc. Microlithographic array for macromolecule and cell fractionation
US5637458A (en) * 1994-07-20 1997-06-10 Sios, Inc. Apparatus and method for the detection and assay of organic molecules
JPH10507844A (ja) * 1994-09-09 1998-07-28 ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュラル アンド メカニカル カレッジ マイクロ構造体及びその製造方法
US5645702A (en) * 1995-06-07 1997-07-08 Hewlett-Packard Company Low voltage miniaturized column analytical apparatus and method
US5500071A (en) * 1994-10-19 1996-03-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
JP2001507441A (ja) * 1995-06-08 2001-06-05 ビジブル ジェネティクス インコーポレイテッド 核酸および他の荷電された分子を移動させそして分離するための微小電気泳動チップ
US5646048A (en) * 1995-07-24 1997-07-08 Hewlett-Packard Company Microcolumnar analytical apparatus with microcolumnar flow gating interface and method of using the apparatus
US5650846A (en) * 1995-11-21 1997-07-22 Hewlett-Packard Company Microcolumnar analytical system with optical fiber sensor
EP0862708A4 (de) * 1995-12-18 1998-11-25 Armand P Neukermans Microventil und integriertes mikrofluidsystem
US6221654B1 (en) * 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
US6156273A (en) * 1997-05-27 2000-12-05 Purdue Research Corporation Separation columns and methods for manufacturing the improved separation columns

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US6596144B1 (en) 2003-07-22
EP0985146B1 (de) 2005-03-02
WO1998054568A1 (en) 1998-12-03
EP0985146A1 (de) 2000-03-15
DE69829181T2 (de) 2005-12-29
US6156273A (en) 2000-12-05

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