[go: up one dir, main page]

DE69828063D1 - Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen - Google Patents

Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen

Info

Publication number
DE69828063D1
DE69828063D1 DE1998628063 DE69828063T DE69828063D1 DE 69828063 D1 DE69828063 D1 DE 69828063D1 DE 1998628063 DE1998628063 DE 1998628063 DE 69828063 T DE69828063 T DE 69828063T DE 69828063 D1 DE69828063 D1 DE 69828063D1
Authority
DE
Germany
Prior art keywords
def
cdna
diagnostic
gene
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1998628063
Other languages
English (en)
Other versions
DE69828063T2 (de
Inventor
Lydie Bougueleret
Ilya Chumakov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Biodevelopment SAS
Original Assignee
Genset SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset SA filed Critical Genset SA
Publication of DE69828063D1 publication Critical patent/DE69828063D1/de
Application granted granted Critical
Publication of DE69828063T2 publication Critical patent/DE69828063T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4721—Cationic antimicrobial peptides, e.g. defensins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
DE69828063T 1997-08-29 1998-08-28 Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen Expired - Lifetime DE69828063T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9710823A FR2767832B1 (fr) 1997-08-29 1997-08-29 Polypeptide defensine humaine def-x, adn genomique et adnc, composition les contenant et applications au diagnostic et au traitement therapeutique
FR9710823 1997-08-29
PCT/FR1998/001864 WO1999011663A1 (fr) 1997-08-29 1998-08-28 DEFENSINE HUMAINE DEF-X, GENE ET cDNA, COMPOSITION LES CONTENANT ET APPLICATIONS AU DIAGNOSTIC ET A LA THERAPIE

Publications (2)

Publication Number Publication Date
DE69828063D1 true DE69828063D1 (de) 2005-01-13
DE69828063T2 DE69828063T2 (de) 2005-12-01

Family

ID=9510617

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69828063T Expired - Lifetime DE69828063T2 (de) 1997-08-29 1998-08-28 Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen

Country Status (11)

Country Link
US (3) US6329340B1 (de)
EP (1) EP1009767B1 (de)
JP (1) JP2001514264A (de)
AT (1) ATE284414T1 (de)
AU (1) AU759482B2 (de)
CA (1) CA2299560C (de)
DE (1) DE69828063T2 (de)
ES (1) ES2230714T3 (de)
FR (1) FR2767832B1 (de)
PT (1) PT1009767E (de)
WO (1) WO1999011663A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984622B2 (en) * 1998-03-25 2006-01-10 The Regents Of The University Of California Use of lipopolysaccharides to manage corneal infections and wounds
US6335318B1 (en) * 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
US7511015B2 (en) * 2002-02-19 2009-03-31 The United States Of America As Represented By The Department Of Health And Human Services Modified defensins and their use
US7119070B2 (en) 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
CA2487895A1 (en) * 2002-05-31 2003-12-11 Ciphergen Biosystems, Inc. Defensins: use as antiviral agents
US20040096820A1 (en) * 2002-05-31 2004-05-20 Ciphergen Biosystems, Inc. Comparative proteomics of progressor and nonprogressor populations
CA2491094A1 (en) * 2002-07-01 2004-01-08 Univesity Of Rochester Medical Center Method for determination of likelihood of occurrence of preterm labor in pregnant females
GB0223655D0 (en) * 2002-10-10 2002-11-20 Mabtech Ab Method of diagnosis
MXPA05006359A (es) * 2002-12-19 2006-02-08 Yitzchak Hillman Tratamiento de la enfermedad a traves de inhibidores peptidos antimicrobianos.
CA2526878A1 (en) * 2003-04-08 2004-10-21 Colotech A/S A method for detection of colorectal cancer in human samples
US9044438B2 (en) 2005-06-17 2015-06-02 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US10967031B2 (en) 2010-12-28 2021-04-06 Kamedis Ltd. Synergistic herbal compositions with prebiotic properties for treatment of skin infections, allergies and inflammation
WO2012090205A2 (en) 2010-12-28 2012-07-05 Kamedis Ltd. Plant extracts for the treatment and prevention of infections
SI3586821T1 (sl) * 2014-06-18 2022-04-29 Medical Technologies, LLC Sestavki in postopki za stimuliranje matičnih celic
RU2597789C2 (ru) * 2014-11-10 2016-09-20 Илья Владимирович Духовлинов Анальгетическое средство на основе плазмидной днк, кодирующей hnp-1, либо hnp-2, либо hnp-3 (варианты)
WO2024036134A2 (en) * 2022-08-08 2024-02-15 Sri International Defensin proteins for infection assessment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
AU4381493A (en) * 1992-05-22 1993-12-30 Children's Hospital Of Philadelphia, The Gastrointestinal defensins, CDNA sequences and method for the production and use thereof
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5550109A (en) * 1994-05-24 1996-08-27 Magainin Pharmaceuticals Inc. Inducible defensin peptide from mammalian epithelia

Also Published As

Publication number Publication date
EP1009767A1 (de) 2000-06-21
EP1009767B1 (de) 2004-12-08
CA2299560C (fr) 2012-03-20
ATE284414T1 (de) 2004-12-15
CA2299560A1 (fr) 1999-03-11
US7105651B2 (en) 2006-09-12
DE69828063T2 (de) 2005-12-01
WO1999011663A1 (fr) 1999-03-11
PT1009767E (pt) 2005-02-28
US20020115151A1 (en) 2002-08-22
US20020182703A1 (en) 2002-12-05
FR2767832A1 (fr) 1999-03-05
ES2230714T3 (es) 2005-05-01
US6960441B2 (en) 2005-11-01
AU9079898A (en) 1999-03-22
US6329340B1 (en) 2001-12-11
FR2767832B1 (fr) 2001-08-10
AU759482B2 (en) 2003-04-17
JP2001514264A (ja) 2001-09-11

Similar Documents

Publication Publication Date Title
DE69828063D1 (de) Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen
BR0315688A (pt) Compostos, composições farmacêuticas e seus usos no tratamento ou prevenção de doenças ou condições de proliferação celular metabólicas
TR200200938T2 (tr) CCR5 modülatörleri olarak piperidinler
BRPI0412993A (pt) inibidores da atividade da akt
BRPI0412845A (pt) herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo
DE69433562D1 (de) Prosaposin und cytokinabhängige peptide als therapeutisch wirksame mittel
PT1131065E (pt) Fumaratos dialquilicos para o tratamento de doencas autoimunes
ATE389724T1 (de) Menschliche dnase i hyperaktive varianten
HK1026144A1 (en) Aryl ureas for the treatment of inflammatory or immunomodulatory diseases.
GEP19991538B (en) Derivatives of Erytromycin and Pharmaceutical Composition on their Basis
TR200103560T2 (tr) Göğüs kanserinin teşhis ve tedavisi için bileşimler ve bunların kullanımı
CA2294516A1 (en) Ikk-.beta. proteins, nucleic acids and methods
DE60239707D1 (de) Antimikrobielle kationische peptide und diese enthaltende formulierungen
DE69905170T2 (de) Thiazolopyrimidinderivate
ITMI20041550A1 (it) Uso di batteri probiotici per la preparazione di composizioni topiche per la protezione dell'epidermide
ATE293700T1 (de) Adenovirus mit glutathion peroxydate gene
BR0110049A (pt) Agonista de cxcr4, uso de um agonista de cxcr4, e composição farmacêutica
ATE500277T1 (de) Hybridpeptide für die behandlung von bacteraemie und sepsis
ATE400294T1 (de) Neue antimikrobielle polypeptide und verfahren für ihre verwendung.
AR008847A1 (es) Construcciones de acidos nucleicos para la expresion regulada de un transgen en una celula hospedante para uso en la terapia fenica y lamanipulacion genetica, una celula aislada que los comprende y una composicion farmaceutica
BR0010563A (pt) Composições isoladas de células da pele e métodos para seu uso
BR9710899A (pt) Composição compreendendo mupirocin e clorohexidina.
BR0206852A (pt) Conjugados de polìmero de neublastina e métodos para uso dos mesmos
BR0010983A (pt) Preparações para a aplicação de agentes antiinflamatórios
CA2265444A1 (en) Tnf-beta-like protein for treating prostate cancer, and related nucleic acid molecules, pharmaceutical compositions and methods

Legal Events

Date Code Title Description
8364 No opposition during term of opposition