DE69827240D1 - Verfahren zur herstellung von eprosartan - Google Patents

Verfahren zur herstellung von eprosartan

Info

Publication number: DE69827240D1
Authority: DE; Germany
Prior art keywords: eprosartan; producing; producing eprosartan
Prior art date: 1997-02-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69827240T

Other languages

English (en)

Other versions

DE69827240T2 (de

Inventor

Robert Flisak

Li Liu

S Labaw

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-02-14

Filing date

1998-02-13

Publication date

2004-12-02

1998-02-13 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

2004-12-02 Application granted granted Critical

2004-12-02 Publication of DE69827240D1 publication Critical patent/DE69827240D1/de

2005-10-13 Publication of DE69827240T2 publication Critical patent/DE69827240T2/de

2018-02-14 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)

DE69827240T 1997-02-14 1998-02-13 Verfahren zur herstellung von eprosartan Expired - Lifetime DE69827240T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3819597P	1997-02-14	1997-02-14
US38195P		1997-02-14
PCT/US1998/002412 WO1998035963A1 (en)	1997-02-14	1998-02-13	Process for preparing eprosartan

Publications (2)

Publication Number	Publication Date
DE69827240D1 true DE69827240D1 (de)	2004-12-02
DE69827240T2 DE69827240T2 (de)	2005-10-13

Family

ID=21898583

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69827240T Expired - Lifetime DE69827240T2 (de)	1997-02-14	1998-02-13	Verfahren zur herstellung von eprosartan

Country Status (41)

Country	Link
US (1)	US6172237B1 (de)
EP (1)	EP0970073B1 (de)
JP (1)	JP4537499B2 (de)
KR (1)	KR100573638B1 (de)
CN (1)	CN1085208C (de)
AP (1)	AP1128A (de)
AR (1)	AR011125A1 (de)
AT (1)	ATE280765T1 (de)
AU (1)	AU730383B2 (de)
BG (1)	BG63804B1 (de)
BR (1)	BR9808664A (de)
CA (1)	CA2281708C (de)
CO (1)	CO4950550A1 (de)
CY (1)	CY2555B1 (de)
CZ (1)	CZ296349B6 (de)
DE (1)	DE69827240T2 (de)
DK (1)	DK0970073T3 (de)
EA (1)	EA001659B1 (de)
EG (1)	EG23935A (de)
ES (1)	ES2231963T3 (de)
HU (1)	HU228781B1 (de)
ID (1)	ID23181A (de)
IL (1)	IL131309A (de)
IN (2)	IN187999B (de)
MA (1)	MA24470A1 (de)
MY (1)	MY118704A (de)
NO (1)	NO317194B1 (de)
NZ (1)	NZ337180A (de)
OA (1)	OA11146A (de)
PE (1)	PE59299A1 (de)
PL (1)	PL192838B1 (de)
PT (1)	PT970073E (de)
RO (1)	RO119719B1 (de)
SA (1)	SA98190082B1 (de)
SI (1)	SI0970073T1 (de)
SK (1)	SK285036B6 (de)
TR (1)	TR199901936T2 (de)
TW (1)	TW399050B (de)
UA (1)	UA54487C2 (de)
WO (1)	WO1998035963A1 (de)
ZA (1)	ZA981207B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20100137613A1 (en) *	2006-12-27	2010-06-03	Hetero Drugs Limited	Process for eprosartan
WO2009013760A2 (en) *	2007-07-25	2009-01-29	Hetero Drugs Limited	Eprosartan mesylate crystalline particles and a process for preparing pure eprosartan
EP2295430A3 (de) *	2007-07-25	2011-08-03	Hetero Drugs Limited	Kristalliner Feststoff von Eprosartanacetat
WO2009084028A2 (en) *	2007-12-03	2009-07-09	Neuland Laboratories Ltd	Improved process for manufacturing anhydrous (e)-3-[2-butyl-1- {(4-carboxyphenyl) methyl}-1h-imidazole-5-yl]-(thiophen-2- ylmethyl)prop-2-enoic acid methane sulfonate
CN101215284B (zh) *	2007-12-31	2010-10-13	浙江华海药业股份有限公司	一种改进的依普罗沙坦的制备方法
US20110054186A1 (en) *	2008-03-31	2011-03-03	Hetero Research Foundation	Process for eprosartan intermediate
WO2010023688A2 (en) *	2008-08-25	2010-03-04	Matrix Laboratories Limited	An improved process for the preparation of eprosartan
WO2011004384A2 (en)	2009-06-05	2011-01-13	Glochem Industries Limited	Process for the preparation of eprosartan
WO2011051975A1 (en)	2009-10-30	2011-05-05	Matrix Laboratories Ltd	An improved process for the preparation of pure eprosartanand its pharmaceutical acceptable salts

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5185351A (en) *	1989-06-14	1993-02-09	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids useful as angiotensin II receptor antagonists
NZ239161A (en) *	1990-07-31	1994-01-26	Smithkline Beecham Corp	Substituted [1h-imidazol-5-yl] alkanoic acid derivatives; medicaments,
AU9137791A (en) *	1990-12-14	1992-07-08	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids
US5395847A (en) *	1993-12-02	1995-03-07	Smithkline Beecham Corporation	Imidazolyl-alkenoic acids
NZ285588A (en) *	1994-05-20	1997-12-19	Smithkline Beecham Corp	[2-butyl-3-(4-carboxybenzyl)-1h-imidazolium-4-yl]-hydroxymethyl sulphonate

1998
- 1998-02-10 AR ARP980100585A patent/AR011125A1/es active IP Right Grant
- 1998-02-11 EG EG15598A patent/EG23935A/xx active
- 1998-02-12 MY MYPI98000577A patent/MY118704A/en unknown
- 1998-02-12 PE PE1998000101A patent/PE59299A1/es not_active Application Discontinuation
- 1998-02-12 MA MA24961A patent/MA24470A1/fr unknown
- 1998-02-12 IN IN360DE1998 patent/IN187999B/en unknown
- 1998-02-13 ES ES98906229T patent/ES2231963T3/es not_active Expired - Lifetime
- 1998-02-13 SI SI9830722T patent/SI0970073T1/xx unknown
- 1998-02-13 UA UA99084635A patent/UA54487C2/uk unknown
- 1998-02-13 TR TR1999/01936T patent/TR199901936T2/xx unknown
- 1998-02-13 CN CN98802484A patent/CN1085208C/zh not_active Expired - Fee Related
- 1998-02-13 JP JP52813798A patent/JP4537499B2/ja not_active Expired - Fee Related
- 1998-02-13 AU AU61508/98A patent/AU730383B2/en not_active Ceased
- 1998-02-13 DE DE69827240T patent/DE69827240T2/de not_active Expired - Lifetime
- 1998-02-13 NZ NZ337180A patent/NZ337180A/xx unknown
- 1998-02-13 ID IDW990839A patent/ID23181A/id unknown
- 1998-02-13 ZA ZA981207A patent/ZA981207B/xx unknown
- 1998-02-13 EA EA199900740A patent/EA001659B1/ru not_active IP Right Cessation
- 1998-02-13 CA CA002281708A patent/CA2281708C/en not_active Expired - Fee Related
- 1998-02-13 BR BR9808664-2A patent/BR9808664A/pt not_active IP Right Cessation
- 1998-02-13 EP EP98906229A patent/EP0970073B1/de not_active Expired - Lifetime
- 1998-02-13 US US09/355,185 patent/US6172237B1/en not_active Expired - Lifetime
- 1998-02-13 PL PL335075A patent/PL192838B1/pl unknown
- 1998-02-13 WO PCT/US1998/002412 patent/WO1998035963A1/en not_active Ceased
- 1998-02-13 CO CO98007700A patent/CO4950550A1/es unknown
- 1998-02-13 CZ CZ0285299A patent/CZ296349B6/cs not_active IP Right Cessation
- 1998-02-13 DK DK98906229T patent/DK0970073T3/da active
- 1998-02-13 KR KR1019997007273A patent/KR100573638B1/ko not_active Expired - Fee Related
- 1998-02-13 PT PT98906229T patent/PT970073E/pt unknown
- 1998-02-13 RO RO99-00885A patent/RO119719B1/ro unknown
- 1998-02-13 SK SK1087-99A patent/SK285036B6/sk not_active IP Right Cessation
- 1998-02-13 AT AT98906229T patent/ATE280765T1/de active
- 1998-02-13 HU HU0001994A patent/HU228781B1/hu not_active IP Right Cessation
- 1998-02-13 IL IL13130998A patent/IL131309A/en not_active IP Right Cessation
- 1998-02-13 AP APAP/P/1999/001620A patent/AP1128A/en active
- 1998-04-15 TW TW087101969A patent/TW399050B/zh not_active IP Right Cessation
- 1998-05-24 SA SA98190082A patent/SA98190082B1/ar unknown
1999
- 1999-08-10 BG BG103650A patent/BG63804B1/bg unknown
- 1999-08-13 NO NO19993913A patent/NO317194B1/no not_active IP Right Cessation
- 1999-08-13 OA OA9900179A patent/OA11146A/en unknown
2002
- 2002-01-28 IN IN58DE2002 patent/IN192743B/en unknown
2006
- 2006-04-07 CY CY0600011A patent/CY2555B1/xx unknown

Also Published As

Publication number	Publication date
IL131309A0 (en)	2001-01-28
AR011125A1 (es)	2000-08-02
IN192743B (de)	2004-05-15
BG63804B1 (bg)	2003-01-31
CO4950550A1 (es)	2000-09-01
NO317194B1 (no)	2004-09-13
IN187999B (de)	2002-08-03
CY2555B1 (en)	2008-07-02
SI0970073T1 (en)	2005-02-28
ID23181A (id)	2000-03-23
CN1085208C (zh)	2002-05-22
OA11146A (en)	2003-04-16
RO119719B1 (ro)	2005-02-28
NO993913L (no)	1999-08-13
BG103650A (en)	2000-06-30
WO1998035963A1 (en)	1998-08-20
CZ285299A3 (cs)	2000-02-16
BR9808664A (pt)	2000-07-11
ATE280765T1 (de)	2004-11-15
ZA981207B (en)	1998-11-12
DE69827240T2 (de)	2005-10-13
CA2281708C (en)	2007-08-14
EP0970073A1 (de)	2000-01-12
NZ337180A (en)	2000-11-24
SK285036B6 (sk)	2006-05-04
ES2231963T3 (es)	2005-05-16
AU6150898A (en)	1998-09-08
PT970073E (pt)	2005-02-28
TW399050B (en)	2000-07-21
MY118704A (en)	2005-01-31
SA98190082B1 (ar)	2006-08-20
HUP0001994A2 (hu)	2001-06-28
JP4537499B2 (ja)	2010-09-01
NO993913D0 (no)	1999-08-13
TR199901936T2 (xx)	2000-04-21
EG23935A (en)	2008-01-14
AU730383B2 (en)	2001-03-08
US6172237B1 (en)	2001-01-09
HU228781B1 (en)	2013-05-28
HUP0001994A3 (en)	2001-07-30
EA001659B1 (ru)	2001-06-25
PL335075A1 (en)	2000-04-10
EP0970073A4 (de)	2001-01-24
PL192838B1 (pl)	2006-12-29
CA2281708A1 (en)	1998-08-20
PE59299A1 (es)	1999-09-09
UA54487C2 (uk)	2003-03-17
EP0970073B1 (de)	2004-10-27
KR20000071007A (ko)	2000-11-25
CN1247539A (zh)	2000-03-15
MA24470A1 (fr)	1998-10-01
JP2001510466A (ja)	2001-07-31
KR100573638B1 (ko)	2006-04-26
DK0970073T3 (da)	2005-02-21
CZ296349B6 (cs)	2006-02-15
AP1128A (en)	2002-12-06
SK108799A3 (en)	2000-05-16
EA199900740A1 (ru)	2000-02-28
IL131309A (en)	2002-09-12
AP9901620A0 (en)	1999-09-30

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ATA200499A (de)	2001-01-15	Verfahren zur herstellung von hydroxymethylpyridinen
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DE69813588D1 (de)	2003-05-22	Verfahren zur herstellung von 3-ispchromanon
DE59802548D1 (de)	2002-01-31	Verfahren zur herstellung von webware
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Legal Events

Date	Code	Title	Description
2005-11-24	8364	No opposition during term of opposition