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DE69822937D1 - Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen - Google Patents

Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen

Info

Publication number
DE69822937D1
DE69822937D1 DE69822937T DE69822937T DE69822937D1 DE 69822937 D1 DE69822937 D1 DE 69822937D1 DE 69822937 T DE69822937 T DE 69822937T DE 69822937 T DE69822937 T DE 69822937T DE 69822937 D1 DE69822937 D1 DE 69822937D1
Authority
DE
Germany
Prior art keywords
cerebral
preventing
present
diseases
various
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69822937T
Other languages
English (en)
Other versions
DE69822937T2 (de
Inventor
Hiroshi Nagase
Yoshifumi Imamura
Junichi Hirokawa
Susumu Matsuda
Yasushi Miyauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of DE69822937D1 publication Critical patent/DE69822937D1/de
Publication of DE69822937T2 publication Critical patent/DE69822937T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69822937T 1997-01-16 1998-01-13 Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen Expired - Fee Related DE69822937T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP582997 1997-01-16
JP582997 1997-01-16
PCT/JP1998/000092 WO1998031684A1 (fr) 1997-01-16 1998-01-13 Derives d'indolomorphinane et medicaments/remedes preventifs contre les troubles cerebraux

Publications (2)

Publication Number Publication Date
DE69822937D1 true DE69822937D1 (de) 2004-05-13
DE69822937T2 DE69822937T2 (de) 2004-08-12

Family

ID=11621945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69822937T Expired - Fee Related DE69822937T2 (de) 1997-01-16 1998-01-13 Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen

Country Status (12)

Country Link
US (1) US6156762A (de)
EP (1) EP0894799B1 (de)
JP (1) JP4110579B2 (de)
KR (1) KR100557804B1 (de)
CN (1) CN1117754C (de)
AT (1) ATE263769T1 (de)
AU (1) AU739367B2 (de)
DE (1) DE69822937T2 (de)
ES (1) ES2217533T3 (de)
NO (1) NO984263L (de)
NZ (1) NZ331769A (de)
WO (1) WO1998031684A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19939044A1 (de) * 1999-08-18 2001-03-15 Gruenenthal Gmbh Verwendung von Morphinanderivaten als Arzneimittel
WO2001014383A1 (fr) * 1999-08-24 2001-03-01 Toray Industries, Inc. Remedes contre les douleurs neuropathiques et modeles animaux de douleurs neuropathiques
DE60231202D1 (de) 2001-05-04 2009-04-02 Amgen Inc Kondensierte heterozyklische verbindungen
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
BR0316070A (pt) 2002-11-06 2005-09-27 Tularik Inc Composto, composição farmacêutica, uso de um composto e, método para modular mchr
US20100172909A1 (en) * 2005-10-24 2010-07-08 Masahiro Nishibori Cerebral edema suppressant
WO2011009020A2 (en) 2009-07-16 2011-01-20 Mallinckrodt Inc. Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
WO2016167318A1 (ja) * 2015-04-16 2016-10-20 学校法人北里研究所 記憶改善剤及びその使用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JPH03218313A (ja) * 1989-11-22 1991-09-25 Toray Ind Inc 脳細胞保護剤
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5223507A (en) * 1992-01-21 1993-06-29 G. D. Searle & Co. Method of using opioid compounds as delta opioid selective agonist analgesics
US5852030A (en) * 1992-09-29 1998-12-22 Toray Industries, Inc. Indole derivatives, process for producing the same and medicinal uses of the same
KR100301093B1 (ko) * 1992-09-29 2001-10-22 히라이 가쯔히꼬 인돌유도체,그제조방법및그의약용도
EP0636371B1 (de) * 1992-12-22 1998-05-20 Toray Industries, Inc. Antitussivum
KR100341950B1 (ko) * 1993-07-19 2002-11-29 도레이 가부시끼가이샤 뇌세포보호제
DE69424853T2 (de) * 1993-07-23 2000-10-05 Toray Industries, Inc. Morphinan-derivate und ihre medizinische verwendung
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II
SE9401727D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds I

Also Published As

Publication number Publication date
NZ331769A (en) 2000-05-26
AU739367B2 (en) 2001-10-11
KR100557804B1 (ko) 2006-06-20
EP0894799A4 (de) 2001-08-16
CN1117754C (zh) 2003-08-13
CN1220668A (zh) 1999-06-23
NO984263L (no) 1998-11-13
NO984263D0 (no) 1998-09-15
ES2217533T3 (es) 2004-11-01
KR20000064618A (ko) 2000-11-06
WO1998031684A1 (fr) 1998-07-23
ATE263769T1 (de) 2004-04-15
DE69822937T2 (de) 2004-08-12
EP0894799B1 (de) 2004-04-07
US6156762A (en) 2000-12-05
JP4110579B2 (ja) 2008-07-02
EP0894799A1 (de) 1999-02-03
AU5343798A (en) 1998-08-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee