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DE69820634D1 - Polyhydroxyalkylpyrazine derivate,deren herstellung und diese enthaltende arzneimitteln - Google Patents

Polyhydroxyalkylpyrazine derivate,deren herstellung und diese enthaltende arzneimitteln

Info

Publication number
DE69820634D1
DE69820634D1 DE69820634T DE69820634T DE69820634D1 DE 69820634 D1 DE69820634 D1 DE 69820634D1 DE 69820634 T DE69820634 T DE 69820634T DE 69820634 T DE69820634 T DE 69820634T DE 69820634 D1 DE69820634 D1 DE 69820634D1
Authority
DE
Germany
Prior art keywords
substituents
chain
ch2or8
production
products containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69820634T
Other languages
English (en)
Other versions
DE69820634T2 (de
Inventor
Herve Bouchard
Alain Commercon
Jean-Francois Peyronel
Corinne Terrier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE69820634D1 publication Critical patent/DE69820634D1/de
Application granted granted Critical
Publication of DE69820634T2 publication Critical patent/DE69820634T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69820634T 1997-07-18 1998-07-15 Polyhydroxyalkylpyrazine derivate,deren herstellung und diese enthaltende arzneimitteln Expired - Lifetime DE69820634T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9709186A FR2766185B1 (fr) 1997-07-18 1997-07-18 Medicaments contenant en tant que principe actif au moins un derive substitue de polyhydroxylalkylpyrazines, les nouveaux derives polyhydroxylalkylpyrazines et leur preparation
PCT/FR1998/001545 WO1999003843A1 (fr) 1997-07-18 1998-07-15 Derives de polyhydroxyalkylpyrazines, leur preparation et medicaments les contenant

Publications (2)

Publication Number Publication Date
DE69820634D1 true DE69820634D1 (de) 2004-01-29
DE69820634T2 DE69820634T2 (de) 2004-10-21

Family

ID=9509395

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69820634T Expired - Lifetime DE69820634T2 (de) 1997-07-18 1998-07-15 Polyhydroxyalkylpyrazine derivate,deren herstellung und diese enthaltende arzneimitteln

Country Status (12)

Country Link
US (1) US6380197B1 (de)
EP (1) EP1001943B1 (de)
JP (1) JP4443035B2 (de)
AT (1) ATE256668T1 (de)
AU (1) AU8810598A (de)
DE (1) DE69820634T2 (de)
DK (1) DK1001943T3 (de)
ES (1) ES2209186T3 (de)
FR (1) FR2766185B1 (de)
PT (1) PT1001943E (de)
WO (1) WO1999003843A1 (de)
ZA (1) ZA986330B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2788274B1 (fr) * 1999-01-11 2001-02-09 Aventis Pharma Sa Nouveaux derives de polyhydroxypyrazines, leur preparation et les compositions pharmaceutiques qui les contiennent
KR20090095626A (ko) 2006-12-04 2009-09-09 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 쿠프레독신과 ＣｐＧ 리치 ＤＮＡ를 이용한 조성물 및 암 치료 방법
US8011596B2 (en) * 2008-02-13 2011-09-06 Hand Held Products, Inc. Machine readable 2D symbology printable on demand
KR20220051164A (ko) 2019-07-05 2022-04-26 아이오엠엑스 테라퓨틱스 아게 Igsf11 (vsig3)의 항체 결합 igc2 및 이의 용도
WO2022008027A1 (en) 2020-07-06 2022-01-13 Iomx Therapeutics Ag Antibodies binding igv of igsf11 (vsig3) and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3443141B2 (ja) * 1993-10-05 2003-09-02 株式会社リコー 画像傾き検出方法及び表処理方法
FR2744365B1 (fr) 1996-02-06 1998-02-27 Inst Malgache Rech Appl Melanges isolables a partir de graines d'eugenia jambolana lamarck, leur preparation et l'utilisation de ces melanges et certains de leurs constituants comme medicaments

Also Published As

Publication number Publication date
ZA986330B (en) 1999-02-08
ES2209186T3 (es) 2004-06-16
ATE256668T1 (de) 2004-01-15
WO1999003843A1 (fr) 1999-01-28
JP2001510187A (ja) 2001-07-31
AU8810598A (en) 1999-02-10
DE69820634T2 (de) 2004-10-21
EP1001943B1 (de) 2003-12-17
PT1001943E (pt) 2004-07-30
EP1001943A1 (de) 2000-05-24
JP4443035B2 (ja) 2010-03-31
FR2766185A1 (fr) 1999-01-22
FR2766185B1 (fr) 2001-06-15
DK1001943T3 (da) 2004-03-29
US6380197B1 (en) 2002-04-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC