DE69813634D1 - REMOVAL OF DISINFECTANT COLORS - Google Patents
REMOVAL OF DISINFECTANT COLORSInfo
- Publication number
- DE69813634D1 DE69813634D1 DE69813634T DE69813634T DE69813634D1 DE 69813634 D1 DE69813634 D1 DE 69813634D1 DE 69813634 T DE69813634 T DE 69813634T DE 69813634 T DE69813634 T DE 69813634T DE 69813634 D1 DE69813634 D1 DE 69813634D1
- Authority
- DE
- Germany
- Prior art keywords
- disinfectant
- blood
- dyes
- dye
- filter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000645 desinfectant Substances 0.000 title abstract 5
- 239000003086 colorant Substances 0.000 title 1
- 239000000975 dye Substances 0.000 abstract 5
- 239000008280 blood Substances 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 4
- 239000000463 material Substances 0.000 abstract 3
- 239000007788 liquid Substances 0.000 abstract 2
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 abstract 1
- 239000010836 blood and blood product Substances 0.000 abstract 1
- 229940125691 blood product Drugs 0.000 abstract 1
- 239000001045 blue dye Substances 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 229960000907 methylthioninium chloride Drugs 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000003634 thrombocyte concentrate Substances 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3681—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
- A61M1/3683—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
- A61M1/3686—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
A process for removing disinfectant dye such as methylene blue from blood, a liquid blood fraction or other perishable liquid to which disinfectant dye has been added. The process employs a filter of polyvinyl alcohol-acetal copolymer. This material shows exceptional avidity for disinfectant dyes, readily removing them from blood or blood fractions while having little or no effect on subsequent chemicals analysis of the treated material. The filter material is a porous matrix that releases no particles or fines into the blood product, and its white color readily shows the capture of the blue dye. Disinfectant dyes are used to extend the shelf life of platelet concentrates with the dyes being removed by a PVAA filter prior to transfusion into a patient.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/014863 WO2000003751A1 (en) | 1998-07-16 | 1998-07-16 | Disinfectant dye removal |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69813634D1 true DE69813634D1 (en) | 2003-05-22 |
DE69813634T2 DE69813634T2 (en) | 2004-01-22 |
Family
ID=22267498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69813634T Expired - Lifetime DE69813634T2 (en) | 1998-07-16 | 1998-07-16 | REMOVAL OF DISINFECTANT COLORS |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1094846B1 (en) |
AT (1) | ATE237368T1 (en) |
BR (1) | BR9816174A (en) |
DE (1) | DE69813634T2 (en) |
DK (1) | DK1094846T3 (en) |
ES (1) | ES2197483T3 (en) |
PT (1) | PT1094846E (en) |
WO (1) | WO2000003751A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2797403B1 (en) * | 1999-08-09 | 2002-03-15 | Maco Pharma Sa | TRANSFUSION LINE WITH MEANS FOR FILTERING A COLORED SUBSTANCE |
ATE430474T1 (en) * | 2003-07-11 | 2009-05-15 | Shanbrom Tech Llc | DOUBLE STAINING PROCESS FOR INACTIVATION OF HEMATOGENIC PATHOGENS |
US8475789B2 (en) | 2008-01-22 | 2013-07-02 | Multimerics Aps | Products and methods to prevent infections |
DE102011007742B3 (en) * | 2011-04-20 | 2012-07-26 | Cumdente GmbH | Disinfection device and disinfectant |
US9375426B2 (en) | 2012-08-24 | 2016-06-28 | Suman Kumar Dhar | Method of screening anti-plasmodial activity of acriflavin and acriflavin as an anti-malarial agent |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU698154B2 (en) * | 1993-06-23 | 1998-10-22 | New York Blood Center, Inc., The | System for viral inactivation of blood |
US6319662B1 (en) * | 1993-12-17 | 2001-11-20 | Baxter International Inc. | Method and apparatus for removing viral contaminants from a body fluid |
US5639376A (en) * | 1994-01-10 | 1997-06-17 | Hemasure, Inc. | Process for simultaneously removing leukocytes and methylene blue from plasma |
US5858641A (en) * | 1996-09-17 | 1999-01-12 | Shanbrom Technologies, Llc | Disinfectant dye removal from blood and blood fractions using a porous poly(vinyl alcohol-acetal) copolymer |
AU1056397A (en) * | 1996-11-20 | 1998-06-10 | Edward Shanbrom | Trace capture in biological fluids |
-
1998
- 1998-07-16 DE DE69813634T patent/DE69813634T2/en not_active Expired - Lifetime
- 1998-07-16 ES ES98934629T patent/ES2197483T3/en not_active Expired - Lifetime
- 1998-07-16 DK DK98934629T patent/DK1094846T3/en active
- 1998-07-16 BR BR9816174-1A patent/BR9816174A/en active Search and Examination
- 1998-07-16 PT PT98934629T patent/PT1094846E/en unknown
- 1998-07-16 EP EP98934629A patent/EP1094846B1/en not_active Expired - Lifetime
- 1998-07-16 WO PCT/US1998/014863 patent/WO2000003751A1/en active IP Right Grant
- 1998-07-16 AT AT98934629T patent/ATE237368T1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1094846B1 (en) | 2003-04-16 |
DE69813634T2 (en) | 2004-01-22 |
DK1094846T3 (en) | 2003-07-21 |
EP1094846A1 (en) | 2001-05-02 |
ATE237368T1 (en) | 2003-05-15 |
ES2197483T3 (en) | 2004-01-01 |
WO2000003751A1 (en) | 2000-01-27 |
PT1094846E (en) | 2003-09-30 |
BR9816174A (en) | 2001-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |