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DE69739346D1 - Gereinigtes sr-p70 protein - Google Patents

Gereinigtes sr-p70 protein

Info

Publication number
DE69739346D1
DE69739346D1 DE69739346T DE69739346T DE69739346D1 DE 69739346 D1 DE69739346 D1 DE 69739346D1 DE 69739346 T DE69739346 T DE 69739346T DE 69739346 T DE69739346 T DE 69739346T DE 69739346 D1 DE69739346 D1 DE 69739346D1
Authority
DE
Germany
Prior art keywords
protein
purified
sequences
tumor
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739346T
Other languages
English (en)
Inventor
Daniel Caput
Pascual Ferrara
Ahmed Mourad Kaghad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Application granted granted Critical
Publication of DE69739346D1 publication Critical patent/DE69739346D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Saccharide Compounds (AREA)
DE69739346T 1996-02-02 1997-02-03 Gereinigtes sr-p70 protein Expired - Lifetime DE69739346D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9601309A FR2744455B1 (fr) 1996-02-02 1996-02-02 Nouvelles sequences d'acides nucleiques de la famille des facteurs suppresseurs de tumeurs, produits d'expression correspondants et leurs applications
PCT/FR1997/000214 WO1997028186A1 (fr) 1996-02-02 1997-02-03 PROTEINE PURIFIEE SR-p70

Publications (1)

Publication Number Publication Date
DE69739346D1 true DE69739346D1 (de) 2009-05-20

Family

ID=9488795

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739346T Expired - Lifetime DE69739346D1 (de) 1996-02-02 1997-02-03 Gereinigtes sr-p70 protein

Country Status (16)

Country Link
US (3) US7557187B2 (de)
EP (1) EP0877758B1 (de)
JP (1) JP3447301B2 (de)
AT (1) ATE427959T1 (de)
AU (1) AU1727597A (de)
BR (1) BR9710919A (de)
DE (1) DE69739346D1 (de)
DK (1) DK0877758T3 (de)
ES (1) ES2322971T3 (de)
FR (1) FR2744455B1 (de)
MX (1) MX9806041A (de)
NO (1) NO323285B1 (de)
PT (1) PT877758E (de)
TW (1) TW515802B (de)
WO (1) WO1997028186A1 (de)
ZA (1) ZA97835B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451979B1 (en) 1997-05-12 2002-09-17 Dana-Farber Cancer Institute, Inc. Methods of treatment using NBS-1, antibodies and proteins thereto, and uses of the antibodies
DE19736691A1 (de) * 1997-08-22 1999-02-25 Michael Prof Dr Med Giesing Verfahren zur Charakterisierung und Identifizierung disseminierter und metastasierter Krebszellen
WO1999019357A2 (en) * 1997-10-15 1999-04-22 President And Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
US7294459B1 (en) 1997-10-15 2007-11-13 President And Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
US7030227B1 (en) 1997-10-15 2006-04-18 President & Fellows Of Harvard College Cell regulatory genes, encoded products, and uses related thereto
US7132276B1 (en) * 1998-03-27 2006-11-07 Otsuka Pharmaceutical Co., Ltd Human p51 genes and gene products thereof
US6476206B1 (en) 1998-03-27 2002-11-05 The Johns Hopkins University p40 protein acts as an oncogene
CA2364609A1 (en) * 1999-03-16 2000-09-21 Exelixis, Inc. Insect p53 tumor suppressor genes and proteins
WO2001032838A2 (en) * 1999-10-29 2001-05-10 Chiron Corporation Methods for improving viral vector titers and reducing cell death in cell cultures
CN1296966A (zh) 1999-11-23 2001-05-30 上海博容基因开发有限公司 一种新的多肽——人sr剪接因子52和编码这种多肽的多核苷酸
WO2003025010A2 (en) * 2001-09-17 2003-03-27 Eirx Therapeutics Limited Human delta-n p73 molecules and uses thereof
ITMI20042227A1 (it) * 2004-11-19 2005-02-19 Ist Fisioterap Ospitalroma Peptide in grado di rompere il complesso m-p53-p63, m-p53-p73 e m-p53-relative proteine isoformi formatosi nelle cellule tumorali e relativi impieghi in campo farmacologico

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE118042T1 (de) * 1988-12-22 1995-02-15 Lilly Co Eli Rekombinante dna enthaltende expressionsvektoren und für isopenicillin-n-epimerase-(racemase)- aktivität kodierende dns-verbindungen.
FR2692594A1 (fr) * 1992-06-22 1993-12-24 Perez Jean Claude Le Langage Global de l'Expression des gènes: Applications à l'analyse, au contrôle et à l'optimisation des interactions globales entre Régions non codantes et codantes de divers gènes.
FR2693594B1 (fr) * 1992-07-07 1994-08-26 Thomson Csf Détecteur d'ondes électromagnétiques à puits quantiques.
KR950702632A (ko) * 1992-07-10 1995-07-29 로버트 이. 레비. 생물학적 탈황촉매를 코드화하는 재조합 dna(recombinant dna encoding a desulfurization biocatalyst)
US6051384A (en) * 1992-09-30 2000-04-18 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Method of detecting p53-specific antibodies
US5532348A (en) 1993-07-30 1996-07-02 United States Of America E6 associated protein and methods of use thereof
US5912143A (en) * 1996-12-27 1999-06-15 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a human mage protein homolog
US6451979B1 (en) 1997-05-12 2002-09-17 Dana-Farber Cancer Institute, Inc. Methods of treatment using NBS-1, antibodies and proteins thereto, and uses of the antibodies
AU4706199A (en) 1998-06-24 2000-01-10 Trustees Of The University Of Pennsylvania, The Compositions and methods for inducing apoptosis in e6-expressing cells

Also Published As

Publication number Publication date
DK0877758T3 (da) 2009-07-06
MX9806041A (es) 1998-11-30
ZA97835B (en) 1998-09-10
US20110020951A1 (en) 2011-01-27
JP2000511765A (ja) 2000-09-12
BR9710919A (pt) 1999-08-17
PT877758E (pt) 2009-07-10
EP0877758B1 (de) 2009-04-08
WO1997028186A1 (fr) 1997-08-07
US7557187B2 (en) 2009-07-07
US7838648B2 (en) 2010-11-23
US20090258409A1 (en) 2009-10-15
EP0877758A2 (de) 1998-11-18
AU1727597A (en) 1997-08-22
ES2322971T3 (es) 2009-07-02
US20050202016A1 (en) 2005-09-15
NO983537L (no) 1998-10-02
FR2744455B1 (fr) 1998-04-24
TW515802B (en) 2003-01-01
NO983537D0 (no) 1998-07-31
JP3447301B2 (ja) 2003-09-16
NO323285B1 (no) 2007-02-26
FR2744455A1 (fr) 1997-08-08
ATE427959T1 (de) 2009-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition