DE69727849D1 - Cyclosporin-Emulsionen - Google Patents

Cyclosporin-Emulsionen

Info

Publication number: DE69727849D1
Authority: DE; Germany
Prior art keywords: cyclosporin; oil; emulsions; cyclosporin emulsions; phospholipid
Prior art date: 1996-04-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69727849T

Other languages

English (en)

Other versions

DE69727849T2 (de

Inventor

Indu Parikh

Awadhesh Mishra

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

RTP Pharma Corp

Original Assignee

RTP Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-03

Filing date

1997-04-03

Publication date

2004-04-08

1997-04-03 Application filed by RTP Pharma Corp filed Critical RTP Pharma Corp

2004-04-08 Publication of DE69727849D1 publication Critical patent/DE69727849D1/de

2004-07-29 Application granted granted Critical

2004-07-29 Publication of DE69727849T2 publication Critical patent/DE69727849T2/de

2017-04-04 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
229930105110 Cyclosporin A Natural products 0.000 title abstract 2
108010036949 Cyclosporine Proteins 0.000 title abstract 2
229960001265 ciclosporin Drugs 0.000 title abstract 2
229930182912 cyclosporin Natural products 0.000 title abstract 2
239000000839 emulsion Substances 0.000 title 1
239000008346 aqueous phase Substances 0.000 abstract 1
235000021588 free fatty acids Nutrition 0.000 abstract 1
239000007764 o/w emulsion Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000012071 phase Substances 0.000 abstract 1
150000003904 phospholipids Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Transplantation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

DE69727849T 1996-04-03 1997-04-03 Cyclosporin-Emulsionen Expired - Lifetime DE69727849T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/627,187 US5660858A (en)	1996-04-03	1996-04-03	Cyclosporin emulsions
US627187		1996-04-03

Publications (2)

Publication Number	Publication Date
DE69727849D1 true DE69727849D1 (de)	2004-04-08
DE69727849T2 DE69727849T2 (de)	2004-07-29

Family

ID=24513586

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69727849T Expired - Lifetime DE69727849T2 (de)	1996-04-03	1997-04-03	Cyclosporin-Emulsionen

Country Status (9)

Country	Link
US (1)	US5660858A (de)
EP (1)	EP0799620B1 (de)
JP (1)	JP4212113B2 (de)
AT (1)	ATE260673T1 (de)
AU (1)	AU2588597A (de)
CA (1)	CA2250970C (de)
DE (1)	DE69727849T2 (de)
ES (1)	ES2217368T3 (de)
WO (1)	WO1997036611A1 (de)

Families Citing this family (80)

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PT1154759E (pt)	1998-12-30	2008-11-20	Dexcel Ltd	Concentrado dispersível para administração de ciclosporina
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DE19961733A1 (de) *	1999-12-21	2001-06-28	Ciclomulsion Ag	Cyclosporin(e) enthaltende hypertone pharmazeutische Zubereitung zur Anwendung bei neurologischen Erkrankungen und als Neuroprotektivum sowie Verfahren zu ihrer Herstellung
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GB9601120D0 (en) *	1996-01-19	1996-03-20	Sandoz Ltd	Organic compounds

1996
- 1996-04-03 US US08/627,187 patent/US5660858A/en not_active Expired - Lifetime
1997
- 1997-03-26 JP JP53536797A patent/JP4212113B2/ja not_active Expired - Fee Related
- 1997-03-26 AU AU25885/97A patent/AU2588597A/en not_active Abandoned
- 1997-03-26 CA CA2250970A patent/CA2250970C/en not_active Expired - Fee Related
- 1997-03-26 WO PCT/US1997/004794 patent/WO1997036611A1/en active Search and Examination
- 1997-04-03 ES ES97302298T patent/ES2217368T3/es not_active Expired - Lifetime
- 1997-04-03 AT AT97302298T patent/ATE260673T1/de not_active IP Right Cessation
- 1997-04-03 EP EP97302298A patent/EP0799620B1/de not_active Expired - Lifetime
- 1997-04-03 DE DE69727849T patent/DE69727849T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2217368T3 (es)	2004-11-01
JP2000509021A (ja)	2000-07-18
ATE260673T1 (de)	2004-03-15
WO1997036611A1 (en)	1997-10-09
AU2588597A (en)	1997-10-22
CA2250970C (en)	2012-10-16
EP0799620A1 (de)	1997-10-08
CA2250970A1 (en)	1997-10-09
JP4212113B2 (ja)	2009-01-21
EP0799620B1 (de)	2004-03-03
DE69727849T2 (de)	2004-07-29
US5660858A (en)	1997-08-26

Publication	Publication Date	Title
DE69727849D1 (de)	2004-04-08	Cyclosporin-Emulsionen
KR870002835A (ko)	1987-04-13	이온화성 소수성약제의 약제학적 제조방법
DK0759773T3 (da)	2001-11-26	Tårekirtelspecifikke emulsioner til topisk påføring på okulært væv
AR009110A1 (es)	2000-03-08	Composicion cosmetica para mejorar la calidad de la piel humana
ATE141780T1 (de)	1996-09-15	Öl in wasser emulsionen verwendbar für die herstellung von einer creme
ATE66366T1 (de)	1991-09-15	Kortikoidhaltige zubereitung zur topischen applikation.
ES2197335T3 (es)	2004-01-01	Composiciones topicas que comprenden una emulsion de aceite en agua y un retinoide.
DE50013111D1 (de)	2006-08-17	Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
EP0402090A3 (de)	1991-05-08	Essbare Öl-in-Wasser-Emulsion
ATE380541T1 (de)	2007-12-15	Herstellung von vitaminemulsionen und konzentrate davon
ATE283031T1 (de)	2004-12-15	Nichtirritierende kosmetische und pharmazeutische zusammensetzungen
AR002965A1 (es)	1998-05-27	Emulsión aceite-en agua transparente cuyos glóbulos de aceite tienen un tamaño promedio inferior a 100 nm y que comprede una fase lipídica anfífla, suaplicacion, procedimiento para prepararla, procedimiento de tratamiento no terapeutico que la utiliza y composicion de uso topico que la contiene.
ES2123800T3 (es)	1999-01-16	Composicion para el cuidado de la piel que contiene vaselina emulsionada.
DE69613647D1 (de)	2001-08-09	Wasser-in-Öl-Emulsion enthaltendes kosmetisches Präparat
BR9812934A (pt)	2000-08-08	Composição cosmética para pele
ATE307555T1 (de)	2005-11-15	Klare wasser-in-öl emulsionen
DE69130706D1 (de)	1999-02-11	Verfahren zur beseitigung von ausgelaufendem öl
DE59711769D1 (de)	2004-08-12	Öl-in-wasser-emulsionen zur wiederherstellung der lamellarität der lipidstruktur geschädigter haut
DE50013081D1 (de)	2006-08-10	Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
ES2179008T3 (es)	2003-01-16	Composicion en forma de emulsion de aceite-en-agua que contiene fibras, y sus utilizaciones principalmente cosmeticas.
ES2189891T3 (es)	2003-07-16	Emulsiones de liquidos optimizadas para la hidrolisis y uso de las mismas.
RU95102782A (ru)	1997-02-27	Косметические композиции для местного применения, вызывающие искусственный загар, способ их получения и применение
DE59812416D1 (de)	2005-01-27	Splissregenerierende haarbehandlungsmittel
FR2720228B1 (fr)	1997-12-12	Nouvelles compositions pesticides du type "émulsion huile dans l'eau".
ATE329570T1 (de)	2006-07-15	Emulsion enthaltend siliconöl- und co- lösungsmittelsystem enhaltend fettlösliche kosmetische wirkstoffe und daraus hergestelleten kosmetischen zubereitungen

Legal Events

Date	Code	Title
2005-02-17	8339	Ceased/non-payment of the annual fee
2005-06-30	8370	Indication related to discontinuation of the patent is to be deleted
2005-08-25	8364	No opposition during term of opposition