DE69724944D1 - Peptidverbindungen mit mmp- und tnf-hemmender wirkung - Google Patents
Peptidverbindungen mit mmp- und tnf-hemmender wirkungInfo
- Publication number
- DE69724944D1 DE69724944D1 DE69724944T DE69724944T DE69724944D1 DE 69724944 D1 DE69724944 D1 DE 69724944D1 DE 69724944 T DE69724944 T DE 69724944T DE 69724944 T DE69724944 T DE 69724944T DE 69724944 D1 DE69724944 D1 DE 69724944D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- compounds
- mmp
- subject invention
- inhibiting effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9607249.1A GB9607249D0 (en) | 1996-04-04 | 1996-04-04 | Compounds |
GB9607249 | 1996-04-04 | ||
PCT/GB1997/000959 WO1997037974A1 (en) | 1996-04-04 | 1997-04-04 | Peptidyl compounds having mmp and tnf inhibitory activity |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69724944D1 true DE69724944D1 (de) | 2003-10-23 |
DE69724944T2 DE69724944T2 (de) | 2004-07-15 |
Family
ID=10791700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69724944T Expired - Fee Related DE69724944T2 (de) | 1996-04-04 | 1997-04-04 | Peptidverbindungen mit mmp- und tnf-hemmender wirkung |
Country Status (9)
Country | Link |
---|---|
US (1) | US6090840A (de) |
EP (1) | EP0891329B1 (de) |
JP (1) | JP2000508640A (de) |
AT (1) | ATE250030T1 (de) |
AU (1) | AU713477B2 (de) |
CA (1) | CA2248070A1 (de) |
DE (1) | DE69724944T2 (de) |
GB (1) | GB9607249D0 (de) |
WO (1) | WO1997037974A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040122011A1 (en) * | 1998-12-23 | 2004-06-24 | Pharmacia Corporation | Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy |
FR2797890A1 (fr) * | 1999-08-31 | 2001-03-02 | Pf Medicament | Nouvelle metalloprotease matricielle mmp-24 homologue aux stromelysines |
US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
PT2087908T (pt) | 2001-06-26 | 2018-07-16 | Amgen Inc | Anticorpos contra opgl |
ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
US20100226922A1 (en) * | 2006-06-08 | 2010-09-09 | Dorothea Maetzel | Specific protease inhibitors and their use in cancer therapy |
EP3609877B1 (de) * | 2017-04-14 | 2020-12-23 | Cosma S.p.A. | Verfahren zur herstellung von firocoxib |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9323165D0 (en) * | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
-
1996
- 1996-04-04 GB GBGB9607249.1A patent/GB9607249D0/en active Pending
-
1997
- 1997-04-04 AU AU23025/97A patent/AU713477B2/en not_active Ceased
- 1997-04-04 WO PCT/GB1997/000959 patent/WO1997037974A1/en active IP Right Grant
- 1997-04-04 US US09/155,696 patent/US6090840A/en not_active Expired - Fee Related
- 1997-04-04 EP EP97915607A patent/EP0891329B1/de not_active Expired - Lifetime
- 1997-04-04 AT AT97915607T patent/ATE250030T1/de not_active IP Right Cessation
- 1997-04-04 DE DE69724944T patent/DE69724944T2/de not_active Expired - Fee Related
- 1997-04-04 CA CA002248070A patent/CA2248070A1/en not_active Abandoned
- 1997-04-04 JP JP9535963A patent/JP2000508640A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU713477B2 (en) | 1999-12-02 |
EP0891329A1 (de) | 1999-01-20 |
AU2302597A (en) | 1997-10-29 |
CA2248070A1 (en) | 1997-10-16 |
WO1997037974A1 (en) | 1997-10-16 |
US6090840A (en) | 2000-07-18 |
ATE250030T1 (de) | 2003-10-15 |
EP0891329B1 (de) | 2003-09-17 |
JP2000508640A (ja) | 2000-07-11 |
GB9607249D0 (en) | 1996-06-12 |
DE69724944T2 (de) | 2004-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |