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DE69719265D1 - Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält - Google Patents

Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält

Info

Publication number
DE69719265D1
DE69719265D1 DE69719265T DE69719265T DE69719265D1 DE 69719265 D1 DE69719265 D1 DE 69719265D1 DE 69719265 T DE69719265 T DE 69719265T DE 69719265 T DE69719265 T DE 69719265T DE 69719265 D1 DE69719265 D1 DE 69719265D1
Authority
DE
Germany
Prior art keywords
nicotinamide
composition containing
plasminogen activator
tissue plasminogen
medicinal composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69719265T
Other languages
English (en)
Other versions
DE69719265T2 (de
Inventor
Kazuyuki Nakashima
Yoshitaka Tajima
Shinichi Furukawa
Hiroshi Mizokami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Publication of DE69719265D1 publication Critical patent/DE69719265D1/de
Application granted granted Critical
Publication of DE69719265T2 publication Critical patent/DE69719265T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69719265T 1996-09-06 1997-09-05 Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält Expired - Fee Related DE69719265T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP25775296 1996-09-06
JP12808397 1997-04-30
JP12808497 1997-04-30

Publications (2)

Publication Number Publication Date
DE69719265D1 true DE69719265D1 (de) 2003-04-03
DE69719265T2 DE69719265T2 (de) 2003-12-04

Family

ID=27315682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69719265T Expired - Fee Related DE69719265T2 (de) 1996-09-06 1997-09-05 Medizinische Zusammensetzung die Gewebeplasminogenaktivator und Nikotinamid enthält

Country Status (4)

Country Link
US (1) US6139838A (de)
EP (1) EP0827751B1 (de)
DE (1) DE69719265T2 (de)
DK (1) DK0827751T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20031211A3 (cs) 2000-10-31 2003-09-17 Pharma Mar, S. A. Prostředek kahalalid F, souprava a použití při léčbě karcinomů

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470419A (en) * 1977-11-16 1979-06-06 Wakamoto Pharma Co Ltd Stable urokinase powdery preparaton
DE3273732D1 (en) * 1982-12-30 1986-11-20 Kowa Co Method of producing a tissue plasminogen activator and composition comprising same
EP0156169B1 (de) * 1984-02-29 1991-12-18 Asahi Kasei Kogyo Kabushiki Kaisha Wässrige Lösung eines darin in erhöhter Konzentration aufgelösten Gewebe-Plasminogen-Aktivators und Herstellungsverfahren
GB8508717D0 (en) * 1985-04-03 1985-05-09 Beecham Group Plc Composition
FR2581652B1 (fr) * 1985-04-22 1989-12-22 Genentech Inc Nouveaux mutants de l'activateur tissulaire du plasminogene humain
IL78937A (en) * 1985-05-28 1990-11-29 Wellcome Found Pharmaceutical compositions containing tissue-plasminogen activator
US4929444A (en) * 1985-05-28 1990-05-29 Burroughs Wellcome Co. Low pH pharmaceutical formulation containing t-PA
JPH0672105B2 (ja) * 1985-10-02 1994-09-14 持田製薬株式会社 血栓溶解剤及びその製法
CA1341444C (en) * 1986-01-24 2003-10-21 Margaret Y. Insley Modified tissue plasminogen activator
AU612974B2 (en) * 1986-01-31 1991-07-25 Genetics Institute, Llc Novel thrombolytic proteins
US5589361A (en) * 1986-03-18 1996-12-31 Genentech, Inc. Human tissue-type plasminogen activator variant
JPS6338327A (ja) * 1986-08-04 1988-02-18 Matsushita Electric Ind Co Ltd 加減算計数回路
JPH02504102A (ja) * 1987-06-30 1990-11-29 ジェネンテク，インコーポレイテッド 血管障害治療のための改良法
US4935237A (en) * 1988-03-21 1990-06-19 Genentech, Inc. Processes for the preparation of t-PA mutants
JP2708749B2 (ja) * 1987-08-10 1998-02-04 エーザイ株式会社 修飾型ｔＰＡ含有注射用組成物
IL88247A0 (en) * 1987-11-06 1989-06-30 Genentech Inc Novel human tissue-type plasminogen activator variant
US4898826A (en) * 1987-12-10 1990-02-06 Invitron Corporation Method to solubilize tissue plasminogen activator
JP2504102B2 (ja) 1988-02-17 1996-06-05 日本電気株式会社 逆三角関数演算装置
JPH01221325A (ja) * 1988-03-01 1989-09-04 Wakamoto Pharmaceut Co Ltd 組織プラスミノーゲン活性化因子の安定化方法
US5037646A (en) * 1988-04-29 1991-08-06 Genentech, Inc. Processes for the treatment of vascular disease
JPH0329390A (ja) * 1989-06-26 1991-02-07 Hitachi Aic Inc プリント配線板の製造方法
JP2578506B2 (ja) * 1989-08-10 1997-02-05 住友重機械工業株式会社 射出成形機保圧工程の制御装置及び制御方法
US5242688A (en) * 1990-12-24 1993-09-07 Eli Lilly And Company Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants
JPH0527607A (ja) * 1991-07-19 1993-02-05 Canon Inc 画像形成装置の転写材給送定着装置
JP2971680B2 (ja) * 1991-10-02 1999-11-08 山之内製薬株式会社 組織プラスミノーゲン活性化因子含有組成物
JPH0672105A (ja) * 1992-08-25 1994-03-15 Bridgestone Corp 建設車両用空気入りタイヤ
JPH0699324A (ja) * 1992-09-21 1994-04-12 Power Reactor & Nuclear Fuel Dev Corp マニプレータ爪先用機能別回転式工具
GB9418092D0 (en) * 1994-09-08 1994-10-26 Red Cross Found Cent Lab Blood Organic compounds

Also Published As

Publication number Publication date
EP0827751A2 (de) 1998-03-11
DK0827751T3 (da) 2003-03-31
US6139838A (en) 2000-10-31
EP0827751A3 (de) 1999-02-03
EP0827751B1 (de) 2003-02-26
DE69719265T2 (de) 2003-12-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee