DE69634905D1 - Phosphnatanaloge von Mannose-6-phosphate und deren Verwendung zur Förderung der Heilung von Wunden oder fibrotischen Störungen mit verminderter Narbenbildung - Google Patents
Phosphnatanaloge von Mannose-6-phosphate und deren Verwendung zur Förderung der Heilung von Wunden oder fibrotischen Störungen mit verminderter NarbenbildungInfo
- Publication number
- DE69634905D1 DE69634905D1 DE69634905T DE69634905T DE69634905D1 DE 69634905 D1 DE69634905 D1 DE 69634905D1 DE 69634905 T DE69634905 T DE 69634905T DE 69634905 T DE69634905 T DE 69634905T DE 69634905 D1 DE69634905 D1 DE 69634905D1
- Authority
- DE
- Germany
- Prior art keywords
- wounds
- mannose
- healing
- phosphate
- analogues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- NBSCHQHZLSJFNQ-QTVWNMPRSA-N D-Mannose-6-phosphate Chemical class OC1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O NBSCHQHZLSJFNQ-QTVWNMPRSA-N 0.000 title abstract 2
- 206010052428 Wound Diseases 0.000 title abstract 2
- 208000027418 Wounds and injury Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000003176 fibrotic effect Effects 0.000 title abstract 2
- 230000035876 healing Effects 0.000 title abstract 2
- 230000037390 scarring Effects 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9516012 | 1995-08-04 | ||
GBGB9516012.3A GB9516012D0 (en) | 1995-08-04 | 1995-08-04 | Pharmaceutical composition |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69634905D1 true DE69634905D1 (de) | 2005-08-04 |
DE69634905T2 DE69634905T2 (de) | 2006-04-27 |
Family
ID=10778773
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69626987T Expired - Lifetime DE69626987T2 (de) | 1995-08-04 | 1996-07-31 | Pharmaceutische komposition |
DE69634905T Expired - Lifetime DE69634905T2 (de) | 1995-08-04 | 1996-07-31 | Phosphnatanaloge von Mannose-6-phosphate und deren Verwendung zur Förderung der Heilung von Wunden oder fibrotischen Störungen mit verminderter Narbenbildung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69626987T Expired - Lifetime DE69626987T2 (de) | 1995-08-04 | 1996-07-31 | Pharmaceutische komposition |
Country Status (14)
Country | Link |
---|---|
US (1) | US6140307A (de) |
EP (2) | EP0841931B1 (de) |
JP (2) | JPH11510179A (de) |
AT (2) | ATE298579T1 (de) |
AU (1) | AU719992B2 (de) |
CA (1) | CA2229010C (de) |
DE (2) | DE69626987T2 (de) |
DK (2) | DK1291018T3 (de) |
ES (2) | ES2243657T3 (de) |
GB (1) | GB9516012D0 (de) |
HK (1) | HK1053264A1 (de) |
PT (2) | PT841931E (de) |
WO (1) | WO1997005883A1 (de) |
ZA (1) | ZA966578B (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2304047A (en) * | 1995-08-09 | 1997-03-12 | Univ Manchester | Pharmaceutical compositions containing cytokines |
GB2316002B (en) * | 1996-08-12 | 1998-09-23 | British Tech Group | Mannose-6-phosphate composition and its use in treating fibrotic disorders |
US6093388A (en) * | 1996-08-12 | 2000-07-25 | Btg International Limited | Mannose-6-phosphate composition and its use in treating fibrotic disorders |
AUPQ872300A0 (en) * | 2000-07-11 | 2000-08-03 | Praxis Pharmaceuticals Pty Ltd | Compounds and methods |
ATE440103T1 (de) * | 2003-05-20 | 2009-09-15 | Pharmaxis Pty Ltd | Mannose-6-phosphonat-verbindungen zur behandlung von entzündungskrankheiten |
US20080057072A1 (en) * | 2006-08-31 | 2008-03-06 | Alcon Manufacturing, Ltd. | Antagonists of ci-m6p/igf2r for prevention and treatment of ctgf-mediated ocular disorders |
WO2008144352A1 (en) * | 2007-05-17 | 2008-11-27 | Sunny Biodiscovery, Inc. | Threitol phosphates, salts thereof and methods of use |
GB0724231D0 (en) * | 2007-12-12 | 2008-01-30 | Renono Ltd | Methods for inhibiting scarring |
GB0910078D0 (en) | 2009-06-11 | 2009-07-22 | Renovo Ltd | Uses of mannose-6-phosphate |
GB0916334D0 (en) | 2009-09-17 | 2009-10-28 | Renovo Ltd | Inhibition of tendon adhesions |
GB0916332D0 (en) * | 2009-09-17 | 2009-10-28 | Renovo Ltd | Medicaments |
BR112021002449A2 (pt) * | 2018-08-10 | 2021-05-04 | New York University | método para melhorar a memória em um indivíduo |
CN113164501B (zh) | 2018-08-10 | 2024-08-09 | 纽约大学 | Igf-2受体的激动剂配体治疗安格曼综合征和自闭症的用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4703040A (en) * | 1985-04-03 | 1987-10-27 | Markov Angel K | Treatment of adult respiratory distress syndrome (ARDS) using fructose diphosphate (FDP) |
DE68926746T2 (de) * | 1988-08-19 | 1996-11-28 | Univ Australian | Auf phosphozucker basierende antientzündliche und/oder immunitätsunterdrückende arzneimittel |
SE8904354D0 (sv) * | 1989-12-21 | 1989-12-21 | Matti Siren | A pharmaceutical composition |
GB9205800D0 (en) * | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
DK129293D0 (da) * | 1993-11-16 | 1993-11-16 | Carlsberg Lab | Carbonhydratholdige forbindelser, der kan binde sig til carbonhydratbindende receptorer |
-
1995
- 1995-08-04 GB GBGB9516012.3A patent/GB9516012D0/en active Pending
-
1996
- 1996-07-31 US US09/011,138 patent/US6140307A/en not_active Expired - Fee Related
- 1996-07-31 JP JP9508206A patent/JPH11510179A/ja active Pending
- 1996-07-31 PT PT96925883T patent/PT841931E/pt unknown
- 1996-07-31 CA CA002229010A patent/CA2229010C/en not_active Expired - Fee Related
- 1996-07-31 WO PCT/GB1996/001840 patent/WO1997005883A1/en active IP Right Grant
- 1996-07-31 DE DE69626987T patent/DE69626987T2/de not_active Expired - Lifetime
- 1996-07-31 DK DK02079259T patent/DK1291018T3/da active
- 1996-07-31 EP EP96925883A patent/EP0841931B1/de not_active Expired - Lifetime
- 1996-07-31 DK DK96925883T patent/DK0841931T3/da active
- 1996-07-31 ES ES02079259T patent/ES2243657T3/es not_active Expired - Lifetime
- 1996-07-31 AU AU66248/96A patent/AU719992B2/en not_active Ceased
- 1996-07-31 PT PT02079259T patent/PT1291018E/pt unknown
- 1996-07-31 ES ES96925883T patent/ES2195000T3/es not_active Expired - Lifetime
- 1996-07-31 AT AT02079259T patent/ATE298579T1/de active
- 1996-07-31 EP EP02079259A patent/EP1291018B1/de not_active Expired - Lifetime
- 1996-07-31 DE DE69634905T patent/DE69634905T2/de not_active Expired - Lifetime
- 1996-07-31 AT AT96925883T patent/ATE235245T1/de active
- 1996-08-02 ZA ZA9606578A patent/ZA966578B/xx unknown
-
2003
- 2003-07-28 HK HK03105420A patent/HK1053264A1/xx not_active IP Right Cessation
-
2008
- 2008-04-02 JP JP2008095915A patent/JP2008239625A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2229010C (en) | 2009-06-02 |
CA2229010A1 (en) | 1997-02-20 |
DK1291018T3 (da) | 2005-09-12 |
DE69626987T2 (de) | 2003-12-04 |
ATE298579T1 (de) | 2005-07-15 |
PT1291018E (pt) | 2005-08-31 |
GB9516012D0 (en) | 1995-10-04 |
DK0841931T3 (da) | 2003-04-22 |
EP0841931B1 (de) | 2003-03-26 |
PT841931E (pt) | 2003-06-30 |
JPH11510179A (ja) | 1999-09-07 |
ATE235245T1 (de) | 2003-04-15 |
DE69626987D1 (de) | 2003-04-30 |
DE69634905T2 (de) | 2006-04-27 |
EP1291018A1 (de) | 2003-03-12 |
EP0841931A1 (de) | 1998-05-20 |
AU6624896A (en) | 1997-03-05 |
WO1997005883A1 (en) | 1997-02-20 |
ES2243657T3 (es) | 2005-12-01 |
EP1291018B1 (de) | 2005-06-29 |
JP2008239625A (ja) | 2008-10-09 |
HK1053264A1 (en) | 2003-10-17 |
ES2195000T3 (es) | 2003-12-01 |
US6140307A (en) | 2000-10-31 |
AU719992B2 (en) | 2000-05-18 |
ZA966578B (en) | 1998-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |