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DE69622648D1 - Benzoxalepin-derivate, deren salze und diese enthaltende arzneimittel - Google Patents

Benzoxalepin-derivate, deren salze und diese enthaltende arzneimittel

Info

Publication number
DE69622648D1
DE69622648D1 DE69622648T DE69622648T DE69622648D1 DE 69622648 D1 DE69622648 D1 DE 69622648D1 DE 69622648 T DE69622648 T DE 69622648T DE 69622648 T DE69622648 T DE 69622648T DE 69622648 D1 DE69622648 D1 DE 69622648D1
Authority
DE
Germany
Prior art keywords
benzoxalepine
derivatives
salts
products containing
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69622648T
Other languages
English (en)
Other versions
DE69622648T2 (de
Inventor
Toshio Tatsuoka
Katsuhide Kamei
Noriko Maeda
Teruyoshi Inoue
Mika Nishimura
Ichiro Hirotsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asubio Pharma Co Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Publication of DE69622648D1 publication Critical patent/DE69622648D1/de
Application granted granted Critical
Publication of DE69622648T2 publication Critical patent/DE69622648T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE69622648T 1995-02-10 1996-02-09 Benzoxalepin-derivate, deren salze und diese enthaltende arzneimittel Expired - Lifetime DE69622648T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5830795 1995-02-10
JP4183695 1995-03-01
PCT/JP1996/000294 WO1996024594A1 (fr) 1995-02-10 1996-02-09 Derives de benzodiazepines, sels issus de ces derives, et medicaments a base de ces derives et sels

Publications (2)

Publication Number Publication Date
DE69622648D1 true DE69622648D1 (de) 2002-09-05
DE69622648T2 DE69622648T2 (de) 2003-02-27

Family

ID=26381494

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69622648T Expired - Lifetime DE69622648T2 (de) 1995-02-10 1996-02-09 Benzoxalepin-derivate, deren salze und diese enthaltende arzneimittel

Country Status (10)

Country Link
US (2) US6187769B1 (de)
EP (1) EP0755930B1 (de)
JP (2) JP3164584B2 (de)
KR (1) KR100408379B1 (de)
AU (1) AU709133B2 (de)
CA (1) CA2187541C (de)
DE (1) DE69622648T2 (de)
ES (1) ES2176434T3 (de)
HU (1) HUP9602774A3 (de)
WO (1) WO1996024594A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU727647B2 (en) 1997-05-22 2000-12-21 Daiichi Sankyo Company, Limited Method of production and method of separation of 2,4'-dipyridyl derivatives and methods of production of benzoxazepine derivatives and salts thereof
CN1089760C (zh) * 1997-07-14 2002-08-28 三得利株式会社 4－取代－3－卤代－1,4－苯并氧氮杂䓬衍生物及其盐的制备方法
DE10031391A1 (de) * 2000-07-03 2002-02-07 Knoll Ag Bicyclische Verbindungen und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
US8426427B2 (en) 2007-04-18 2013-04-23 Kissei Pharmaceutical Co., Ltd. Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes
KR20100098491A (ko) * 2007-11-30 2010-09-07 다이이찌 산쿄 가부시키가이샤 파킨슨병의 운동 합병증 또는 정신증상을 개선하는 약제
WO2023192430A1 (en) * 2022-03-30 2023-10-05 University Of Florida Research Foundation, Incorported Compounds for treating psychostimulant misuse
WO2024163956A2 (en) * 2023-02-03 2024-08-08 University Of Florida Research Foundation, Incorporated Sigma receptor ligand compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2865341B2 (ja) * 1988-12-28 1999-03-08 サントリー株式会社 ベンゾオキサゼピン誘導体
ATE112769T1 (de) * 1988-12-28 1994-10-15 Suntory Ltd Benzoxazepinderivate.
JP2935541B2 (ja) * 1990-06-28 1999-08-16 サントリー株式会社 縮合複素環化合物
JP3112728B2 (ja) * 1991-08-21 2000-11-27 サントリー株式会社 ２，３，４，５−テトラヒドロ−１，４−ベンゾオキサゼピン−３，５−ジオンの製造法
US5196428A (en) * 1992-04-03 1993-03-23 Bristol-Myers Squibb Company Imidazo[4,5-b]qinolinyl oxy alkyl ureas

Also Published As

Publication number Publication date
JP3164584B2 (ja) 2001-05-08
HUP9602774A3 (en) 1998-12-28
JP2001058989A (ja) 2001-03-06
CA2187541C (en) 2008-04-08
WO1996024594A1 (fr) 1996-08-15
CA2187541A1 (en) 1996-08-15
KR970702272A (ko) 1997-05-13
EP0755930A1 (de) 1997-01-29
KR100408379B1 (ko) 2004-04-03
JP3995404B2 (ja) 2007-10-24
AU4633796A (en) 1996-08-27
US6187769B1 (en) 2001-02-13
HU9602774D0 (en) 1996-11-28
DE69622648T2 (de) 2003-02-27
AU709133B2 (en) 1999-08-19
EP0755930B1 (de) 2002-07-31
ES2176434T3 (es) 2002-12-01
HUP9602774A2 (en) 1997-11-28
US6337397B1 (en) 2002-01-08
EP0755930A4 (de) 1998-06-10

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: DAICHI SUNTORY PHARMA CO., LTD., TOKIO/TOKYO, JP

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DAIICHI ASUBIO PHARMA CO., LTD., TOKIO/TOKYO, JP

8327 Change in the person/name/address of the patent owner

Owner name: ASUBIO PHARMA CO., LTD., TOKYO, JP

R082 Change of representative

Ref document number: 755930

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Representative=s name: KADOR & PARTNER, 80469 MUENCHEN, DE