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DE69620762D1 - Cardiotropische radiopharmazeutika,die einen übergangsmetall-nitrid-komplex enthalten und die eine rasche myocardial-eliminierung aufweisen - Google Patents

Cardiotropische radiopharmazeutika,die einen übergangsmetall-nitrid-komplex enthalten und die eine rasche myocardial-eliminierung aufweisen

Info

Publication number
DE69620762D1
DE69620762D1 DE69620762T DE69620762T DE69620762D1 DE 69620762 D1 DE69620762 D1 DE 69620762D1 DE 69620762 T DE69620762 T DE 69620762T DE 69620762 T DE69620762 T DE 69620762T DE 69620762 D1 DE69620762 D1 DE 69620762D1
Authority
DE
Germany
Prior art keywords
transition metal
pct
radiopharmic
cardiotropic
elimination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69620762T
Other languages
English (en)
Other versions
DE69620762T2 (de
Inventor
Emmanuel Bellande
Jacques Laine
Veronique Comazzi
Roberto Pasqualini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
CIS Bio International SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CIS Bio International SA filed Critical CIS Bio International SA
Application granted granted Critical
Publication of DE69620762D1 publication Critical patent/DE69620762D1/de
Publication of DE69620762T2 publication Critical patent/DE69620762T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Electrotherapy Devices (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
DE69620762T 1995-07-17 1996-07-16 Cardiotropische radiopharmazeutika,die einen übergangsmetall-nitrid-komplex enthalten und die eine rasche myocardial-eliminierung aufweisen Expired - Fee Related DE69620762T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9508606A FR2736834B1 (fr) 1995-07-17 1995-07-17 Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide
PCT/FR1996/001103 WO1997003705A1 (fr) 1995-07-17 1996-07-16 Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide

Publications (2)

Publication Number Publication Date
DE69620762D1 true DE69620762D1 (de) 2002-05-23
DE69620762T2 DE69620762T2 (de) 2002-11-07

Family

ID=9481036

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69620762T Expired - Fee Related DE69620762T2 (de) 1995-07-17 1996-07-16 Cardiotropische radiopharmazeutika,die einen übergangsmetall-nitrid-komplex enthalten und die eine rasche myocardial-eliminierung aufweisen

Country Status (12)

Country Link
US (1) US6071492A (de)
EP (1) EP0839059B1 (de)
JP (1) JPH11509224A (de)
AT (1) ATE216267T1 (de)
AU (1) AU705807B2 (de)
CA (1) CA2227038A1 (de)
DE (1) DE69620762T2 (de)
DK (1) DK0839059T3 (de)
ES (1) ES2175115T3 (de)
FR (1) FR2736834B1 (de)
PT (1) PT839059E (de)
WO (1) WO1997003705A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1289660B1 (it) * 1996-10-03 1998-10-16 Sorin Biomedica Diagnost Spa Procedimento per la riduzione di composti ossigenati del renio o del tecnezio
DE19860289C2 (de) * 1998-12-21 2003-11-13 Schering Ag Neue Chelatoren sowie deren Tricarbonyl-Komplexe mit Technetium und Rhenium
FR2797769B1 (fr) * 1999-09-01 2003-07-25 Cis Bio Int Produits radiopharmaceutiques et leur procede de preparation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU619538B2 (en) * 1988-03-09 1992-01-30 Cis Bio International Preparation of nitruro compounds usable as radio-pharmaceutical products
DE68909245T2 (de) * 1988-11-25 1994-03-17 Cis Bio International Saclay Übergangsmetall-stickstoffkomplex enthaltendes radiopharmazeutisches produkt mit einer neigung zum herzgewebe.
FR2664166A1 (fr) * 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
WO1992010214A1 (en) * 1990-12-12 1992-06-25 Mallinckrodt Medical, Inc. Method of radioactive labelling of blood cells and kit therefor
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
FR2698272B1 (fr) * 1992-11-20 1994-12-30 Cis Bio Int Procédé de marquage cellulaire au moyen de complexes nitruro-bis (dithiocarbamato)Tc-99m et trousse pour la mise en Óoeuvre de ce procédé.

Also Published As

Publication number Publication date
EP0839059A1 (de) 1998-05-06
PT839059E (pt) 2002-09-30
ATE216267T1 (de) 2002-05-15
US6071492A (en) 2000-06-06
DE69620762T2 (de) 2002-11-07
EP0839059B1 (de) 2002-04-17
AU6617896A (en) 1997-02-18
WO1997003705A1 (fr) 1997-02-06
CA2227038A1 (fr) 1997-02-06
DK0839059T3 (da) 2002-08-12
FR2736834B1 (fr) 1997-08-29
JPH11509224A (ja) 1999-08-17
FR2736834A1 (fr) 1997-01-24
ES2175115T3 (es) 2002-11-16
AU705807B2 (en) 1999-06-03

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SCHERING AG, 13353 BERLIN, DE

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AG, 13353 BERLIN, DE

8327 Change in the person/name/address of the patent owner

Owner name: BAYER SCHERING PHARMA AKIENGESELLSCHAFT, 13353, DE

8339 Ceased/non-payment of the annual fee