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DE69606552D1 - Acylierte enolderivate von alpha-ketoestern und alpha-ketoamiden - Google Patents

Acylierte enolderivate von alpha-ketoestern und alpha-ketoamiden

Info

Publication number
DE69606552D1
DE69606552D1 DE69606552T DE69606552T DE69606552D1 DE 69606552 D1 DE69606552 D1 DE 69606552D1 DE 69606552 T DE69606552 T DE 69606552T DE 69606552 T DE69606552 T DE 69606552T DE 69606552 D1 DE69606552 D1 DE 69606552D1
Authority
DE
Germany
Prior art keywords
alpha
ketoesters
ketoamides
enol derivatives
acylated enol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69606552T
Other languages
English (en)
Other versions
DE69606552T2 (de
Inventor
P Peet
P Burkhart
Shujaath Mehdi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of DE69606552D1 publication Critical patent/DE69606552D1/de
Application granted granted Critical
Publication of DE69606552T2 publication Critical patent/DE69606552T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69606552T 1995-12-01 1996-11-04 Acylierte enolderivate von alpha-ketoestern und alpha-ketoamiden Expired - Fee Related DE69606552T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56619695A 1995-12-01 1995-12-01
PCT/US1996/017752 WO1997020856A1 (en) 1995-12-01 1996-11-04 ACYLATED ENOL DERIVATIVES OF α-KETOESTERS AND α-KETOAMIDES

Publications (2)

Publication Number Publication Date
DE69606552D1 true DE69606552D1 (de) 2000-03-09
DE69606552T2 DE69606552T2 (de) 2000-09-14

Family

ID=24261904

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69606552T Expired - Fee Related DE69606552T2 (de) 1995-12-01 1996-11-04 Acylierte enolderivate von alpha-ketoestern und alpha-ketoamiden

Country Status (20)

Country Link
EP (1) EP0863915B1 (de)
JP (1) JP2000502073A (de)
KR (1) KR19990071822A (de)
CN (1) CN1127512C (de)
AR (1) AR005240A1 (de)
AT (1) ATE189457T1 (de)
AU (1) AU705819B2 (de)
CA (1) CA2239159C (de)
DE (1) DE69606552T2 (de)
ES (1) ES2144788T3 (de)
GR (1) GR3033205T3 (de)
HU (1) HUP9902417A3 (de)
IL (1) IL124499A (de)
MX (1) MX9804265A (de)
NO (1) NO982467L (de)
NZ (1) NZ322731A (de)
PT (1) PT863915E (de)
TW (1) TW419482B (de)
WO (1) WO1997020856A1 (de)
ZA (1) ZA969889B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3359697A (en) * 1996-07-08 1998-02-02 Yamanouchi Pharmaceutical Co., Ltd. Bone resorption inhibitors
US6645939B1 (en) 1997-11-24 2003-11-11 Merck & Co., Inc. Substituted β-alanine derivatives as cell adhesion inhibitors
DE69824037T2 (de) * 1997-11-24 2005-06-02 Merck & Co., Inc. Beta-alanin-derivate als zell-adhäsions-inhibitoren
US20060252698A1 (en) * 2005-04-20 2006-11-09 Malcolm Bruce A Compounds for inhibiting cathepsin activity
KR101012313B1 (ko) * 2008-06-10 2011-02-09 서울대학교산학협력단 염증질환 치료제

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378457A (en) * 1981-12-24 1995-01-03 Virogenetics Corporation Interferon sensitive recombinant poxvirus vaccine
JPH06504547A (ja) * 1990-12-28 1994-05-26 ジョージア・テック・リサーチ・コーポレーション ペプチドケトアミド、ケト酸およびケトエステル

Also Published As

Publication number Publication date
PT863915E (pt) 2000-05-31
TW419482B (en) 2001-01-21
ES2144788T3 (es) 2000-06-16
CN1127512C (zh) 2003-11-12
EP0863915B1 (de) 2000-02-02
EP0863915A1 (de) 1998-09-16
ZA969889B (en) 1997-06-17
NO982467L (no) 1998-08-03
ATE189457T1 (de) 2000-02-15
NZ322731A (en) 1999-10-28
JP2000502073A (ja) 2000-02-22
CN1203602A (zh) 1998-12-30
MX9804265A (es) 1998-09-30
NO982467D0 (no) 1998-05-29
WO1997020856A1 (en) 1997-06-12
CA2239159A1 (en) 1997-06-12
IL124499A0 (en) 1998-12-06
IL124499A (en) 2003-05-29
AU7669796A (en) 1997-06-27
HUP9902417A2 (hu) 1999-11-29
GR3033205T3 (en) 2000-08-31
DE69606552T2 (de) 2000-09-14
CA2239159C (en) 2002-09-10
AR005240A1 (es) 1999-04-28
HUP9902417A3 (en) 2000-11-28
AU705819B2 (en) 1999-06-03
KR19990071822A (ko) 1999-09-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMACEUTICALS INC.(N.D.GES.D.STAATES DEL

8339 Ceased/non-payment of the annual fee