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DE69535707D1 - Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind - Google Patents

Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind

Info

Publication number
DE69535707D1
DE69535707D1 DE69535707T DE69535707T DE69535707D1 DE 69535707 D1 DE69535707 D1 DE 69535707D1 DE 69535707 T DE69535707 T DE 69535707T DE 69535707 T DE69535707 T DE 69535707T DE 69535707 D1 DE69535707 D1 DE 69535707D1
Authority
DE
Germany
Prior art keywords
diagnosis
diseases
treatment
methods
signal transmission
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69535707T
Other languages
English (en)
Other versions
DE69535707T2 (de
Inventor
Ben Lewis Margolis
Joseph Schlessinger
Irit Lax
John E Ladbury
Mark A Lemmon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
New York University NYU
Original Assignee
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York University NYU filed Critical New York University NYU
Publication of DE69535707D1 publication Critical patent/DE69535707D1/de
Application granted granted Critical
Publication of DE69535707T2 publication Critical patent/DE69535707T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DE69535707T 1994-03-14 1995-03-13 Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind Expired - Fee Related DE69535707T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21223494A 1994-03-14 1994-03-14
US212234 1994-03-14
US25578594A 1994-06-08 1994-06-08
US255785 1994-06-08
PCT/US1995/003452 WO1995025166A1 (en) 1994-03-14 1995-03-13 Methods for treatment or diagnosis of diseases or conditions associated with abnormal signal transduction

Publications (2)

Publication Number Publication Date
DE69535707D1 true DE69535707D1 (de) 2008-03-27
DE69535707T2 DE69535707T2 (de) 2009-05-07

Family

ID=26906921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535707T Expired - Fee Related DE69535707T2 (de) 1994-03-14 1995-03-13 Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind

Country Status (5)

Country Link
EP (1) EP0797662B1 (de)
AU (1) AU2187595A (de)
CA (1) CA2187781A1 (de)
DE (1) DE69535707T2 (de)
WO (1) WO1995025166A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU701733B2 (en) * 1995-05-02 1999-02-04 Garvan Institute Of Medical Research GDU, a novel signalling protein
US7396810B1 (en) 2000-08-14 2008-07-08 Oregon Health Sciences University Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
US7625859B1 (en) 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
WO2010033249A2 (en) 2008-09-22 2010-03-25 Massachusetts Institute Of Technology Compositions of and methods using ligand dimers
US9029328B2 (en) 2010-03-24 2015-05-12 The Brigham And Women's Hospital, Inc. Methods for cardioprotection and cardioregeneration with dimers of EGF family ligands

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5183805A (en) * 1990-08-13 1993-02-02 Board Of Regents, The University Of Texas System Bioactive egf peptides for promotion of tissue regeneration and cancer therapy
CA2134544A1 (en) * 1992-04-29 1993-11-11 Ruth Lupu Binding peptides which interact with ligand growth factors of the epidermal growth factor receptor and erbb-2 receptor

Also Published As

Publication number Publication date
EP0797662A1 (de) 1997-10-01
EP0797662B1 (de) 2008-02-13
WO1995025166A1 (en) 1995-09-21
CA2187781A1 (en) 1995-09-21
AU2187595A (en) 1995-10-03
DE69535707T2 (de) 2009-05-07

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DE69535707D1 (de) Methoden zur behandlung oder diagnose von krankheiten oder zuständen, die mit einer abnormalen signalübertragung assoziiert sind
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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee