DE69531627D1 - Humane hypertrophe chrondrozyten zelllinien - Google Patents

Humane hypertrophe chrondrozyten zelllinien

Info

Publication number: DE69531627D1
Authority: DE; Germany
Prior art keywords: hypertrophe; chrondrocyte; humane; cell lines; lines
Prior art date: 1994-12-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69531627T

Other languages

English (en)

Other versions

DE69531627T2 (de

Inventor

Bradley Michael John Stringer

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CellFactors PLC

Original Assignee

CellFactors PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-12-13

Filing date

1995-10-25

Publication date

2003-10-02

1995-10-25 Application filed by CellFactors PLC filed Critical CellFactors PLC

2003-10-02 Application granted granted Critical

2003-10-02 Publication of DE69531627D1 publication Critical patent/DE69531627D1/de

2004-06-17 Publication of DE69531627T2 publication Critical patent/DE69531627T2/de

2015-10-26 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/32—Amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Cell Biology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Botany (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Rheumatology (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Medicinal Chemistry (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Developmental Biology & Embryology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Materials For Medical Uses (AREA)

DE69531627T 1994-12-13 1995-10-25 Humane hypertrophe chrondrozyten zelllinien Expired - Fee Related DE69531627T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB9425071		1994-12-13
GBGB9425071.9A GB9425071D0 (en)	1994-12-13	1994-12-13	Chondrocyte cell lines
PCT/GB1995/002497 WO1996018728A1 (en)	1994-12-13	1995-10-25	Chondrocyte cell-lines

Publications (2)

Publication Number	Publication Date
DE69531627D1 true DE69531627D1 (de)	2003-10-02
DE69531627T2 DE69531627T2 (de)	2004-06-17

Family

ID=10765824

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69531627T Expired - Fee Related DE69531627T2 (de)	1994-12-13	1995-10-25	Humane hypertrophe chrondrozyten zelllinien

Country Status (15)

Country	Link
EP (2)	EP0795008B1 (de)
JP (3)	JPH10510985A (de)
KR (1)	KR980700410A (de)
AT (1)	ATE248218T1 (de)
AU (1)	AU3703795A (de)
CA (1)	CA2207764A1 (de)
CZ (1)	CZ182497A3 (de)
DE (1)	DE69531627T2 (de)
DK (1)	DK0795008T3 (de)
ES (1)	ES2206518T3 (de)
GB (1)	GB9425071D0 (de)
HU (1)	HU221244B1 (de)
MX (1)	MX9704296A (de)
PT (1)	PT795008E (de)
WO (1)	WO1996018728A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005511083A (ja)	2001-12-07	2005-04-28	ジェロンコーポレイション	ヒト胚幹細胞由来の軟骨細胞前駆細胞
JP2006289062A (ja) *	2005-03-18	2006-10-26	Pentax Corp	肥大化能を有する軟骨細胞と足場を用いた骨補填材料
AU2011236653B2 (en)	2010-04-08	2016-10-27	The University Court Of The University Of Edinburgh	Chondrogenic progenitor cells, protocol for derivation of cells and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994009118A1 (en) *	1992-10-13	1994-04-28	The General Hospital Corporation	Immortalized human chondrocytes

1994
- 1994-12-13 GB GBGB9425071.9A patent/GB9425071D0/en active Pending
1995
- 1995-10-25 DK DK95934723T patent/DK0795008T3/da active
- 1995-10-25 KR KR1019970703945A patent/KR980700410A/ko not_active Application Discontinuation
- 1995-10-25 AT AT95934723T patent/ATE248218T1/de not_active IP Right Cessation
- 1995-10-25 ES ES95934723T patent/ES2206518T3/es not_active Expired - Lifetime
- 1995-10-25 WO PCT/GB1995/002497 patent/WO1996018728A1/en not_active Application Discontinuation
- 1995-10-25 JP JP8518391A patent/JPH10510985A/ja not_active Withdrawn
- 1995-10-25 AU AU37037/95A patent/AU3703795A/en not_active Abandoned
- 1995-10-25 HU HU9702182A patent/HU221244B1/hu not_active IP Right Cessation
- 1995-10-25 CZ CZ971824A patent/CZ182497A3/cs unknown
- 1995-10-25 EP EP95934723A patent/EP0795008B1/de not_active Expired - Lifetime
- 1995-10-25 DE DE69531627T patent/DE69531627T2/de not_active Expired - Fee Related
- 1995-10-25 MX MX9704296A patent/MX9704296A/es unknown
- 1995-10-25 EP EP01110823A patent/EP1142989A3/de not_active Withdrawn
- 1995-10-25 CA CA002207764A patent/CA2207764A1/en not_active Abandoned
- 1995-10-25 PT PT95934723T patent/PT795008E/pt unknown
2002
- 2002-10-24 JP JP2002310323A patent/JP2003116533A/ja not_active Withdrawn
2005
- 2005-07-13 JP JP2005205003A patent/JP2005312996A/ja active Pending

Also Published As

Publication number	Publication date
KR980700410A (ko)	1998-03-30
JPH10510985A (ja)	1998-10-27
PT795008E (pt)	2004-01-30
MX9704296A (es)	1998-02-28
ES2206518T3 (es)	2004-05-16
ATE248218T1 (de)	2003-09-15
JP2005312996A (ja)	2005-11-10
EP1142989A3 (de)	2001-11-21
CA2207764A1 (en)	1996-06-20
AU3703795A (en)	1996-07-03
GB9425071D0 (en)	1995-02-08
EP1142989A2 (de)	2001-10-10
CZ182497A3 (en)	1997-11-12
EP0795008A1 (de)	1997-09-17
DE69531627T2 (de)	2004-06-17
HUT77076A (hu)	1998-03-02
DK0795008T3 (da)	2003-12-15
JP2003116533A (ja)	2003-04-22
EP0795008B1 (de)	2003-08-27
HU221244B1 (en)	2002-09-28
WO1996018728A1 (en)	1996-06-20

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TR199900308T2 (xx)	1999-04-21	Tiyenopirimidinler
GT199600026A (es)	1997-11-15	Isotiazolonas
IL192078A0 (en)	2008-12-29	Recombinant ??-l-iduronidase,methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof
TR199701212T1 (xx)	1998-03-21	�drar� tutamama halinin tedavisi i�in alfa IL- agonistlerinin kullan�lmas�.
BG101110A (en)	1997-08-29	Substituted pyrimidine compounds and their application
DK0631619T3 (da)	2000-10-09	Rekonstrueret bruskvæv
EA200100184A1 (ru)	2001-10-22	Новые гидратные формы алендроната натрия, способы их получения и фармацевтические композиции
EP0786995A4 (de)	1997-08-20
ZA986087B (en)	2000-05-16	Induction of male sterility in plants by expression of high levels of avidin.
BG103096A (en)	1999-09-30	Thrombin inhibitors
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ES2123873T3 (es)	1999-01-16	Pirrolocarbazol.
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BR0116128A (pt)	2003-11-04	Processo para inertizar uma cinza proveniente da incineração de rejeitos urbanos e pozolana artificial
TR200200278T2 (tr)	2002-06-21	Kalsilitik bileşimler
DE69531627D1 (de)	2003-10-02	Humane hypertrophe chrondrozyten zelllinien
PL367306A1 (pl)	2005-02-21	Szczepionki na bazie autologicznych komórek T i sposoby ich otrzymywania
BG104292A (en)	2000-12-29	Methods and compositions for the treatment of rheumatoid arthritis
ATE330604T1 (de)	2006-07-15	Behandlung von manischen erkrankungen
MX9708091A (es)	1998-02-28	Metodo de elaboracion de un alimento para animales que tiene una suspension estable de psyllium.

Legal Events

Date	Code	Title	Description
2004-09-23	8364	No opposition during term of opposition
2007-08-23	8339	Ceased/non-payment of the annual fee