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DE69529917D1 - Vernetzte mikropartikel und ihre verwendung als arzneiträger - Google Patents

Vernetzte mikropartikel und ihre verwendung als arzneiträger

Info

Publication number
DE69529917D1
DE69529917D1 DE69529917T DE69529917T DE69529917D1 DE 69529917 D1 DE69529917 D1 DE 69529917D1 DE 69529917 T DE69529917 T DE 69529917T DE 69529917 T DE69529917 T DE 69529917T DE 69529917 D1 DE69529917 D1 DE 69529917D1
Authority
DE
Germany
Prior art keywords
microparticles
networked
medicine
water
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69529917T
Other languages
English (en)
Other versions
DE69529917T2 (de
Inventor
Richard Alan Johnson
Andrew Derek Sutton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Drug Delivery Ltd
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of DE69529917D1 publication Critical patent/DE69529917D1/de
Publication of DE69529917T2 publication Critical patent/DE69529917T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69529917T 1994-12-16 1995-12-14 Vernetzte mikropartikel und ihre verwendung als arzneiträger Expired - Fee Related DE69529917T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94309417 1994-12-16
PCT/GB1995/002925 WO1996018388A2 (en) 1994-12-16 1995-12-14 Cross-linked microparticles and their use as therapeutic vehicles

Publications (2)

Publication Number Publication Date
DE69529917D1 true DE69529917D1 (de) 2003-04-17
DE69529917T2 DE69529917T2 (de) 2003-12-11

Family

ID=8217949

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529917T Expired - Fee Related DE69529917T2 (de) 1994-12-16 1995-12-14 Vernetzte mikropartikel und ihre verwendung als arzneiträger

Country Status (19)

Country Link
EP (1) EP0796090B1 (de)
JP (1) JP4350165B2 (de)
CN (1) CN1175208A (de)
AT (1) ATE234080T1 (de)
AU (1) AU692019B2 (de)
BR (1) BR9510462A (de)
CA (1) CA2207077C (de)
CZ (1) CZ183797A3 (de)
DE (1) DE69529917T2 (de)
DK (1) DK0796090T3 (de)
ES (1) ES2191721T3 (de)
FI (1) FI972546L (de)
HU (1) HUT77369A (de)
NO (1) NO972554L (de)
NZ (1) NZ297072A (de)
PL (1) PL321018A1 (de)
PT (1) PT796090E (de)
WO (1) WO1996018388A2 (de)
ZA (1) ZA9510702B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
GB9423419D0 (en) 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
US5955108A (en) * 1994-12-16 1999-09-21 Quadrant Healthcare (Uk) Limited Cross-linked microparticles and their use as therapeutic vehicles
JP4024302B2 (ja) * 1996-05-17 2007-12-19 クアドラント、 ドラッグ、 デリバリー、 リミテッド 微粒子および創傷治療におけるその用途
GB9610830D0 (en) 1996-05-23 1996-07-31 Andaris Ltd Use of hollow microcapsules
GB9615435D0 (en) * 1996-07-23 1996-09-04 Andaris Ltd Spray-dried product and its therapeutic use
GB9621825D0 (en) * 1996-10-19 1996-12-11 Andaris Ltd Microparticles and their use as therapeutic vehicles
US5961459A (en) * 1996-10-19 1999-10-05 Andaris Limited Use of hollow microcapsules in diagnosis and therapy
ATE284714T1 (de) * 1996-10-21 2005-01-15 Quadrant Drug Delivery Ltd Plättchen-ersatzmittel und geeignetes konjugations-herstellungsverfahren
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
AU5871898A (en) * 1997-01-30 1998-08-25 Andaris Limited Microparticles and their use in cancer treatment
EP1003481A4 (de) 1997-06-05 2002-10-23 Hemosphere Inc Fibrinogen-beschichtete mikrosphären
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
GB9724143D0 (en) 1997-11-14 1998-01-14 Andaris Ltd Pharmaceutical conjugate
GB9825105D0 (en) * 1998-11-16 1999-01-13 Andaris Ltd Pharamaceutical conjugates
DK1280520T4 (en) 2000-05-10 2018-06-25 Novartis Ag Phospholipid based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
MXPA04005865A (es) 2001-12-19 2004-09-13 Nektar Therapeutics Suministro de aminoglucosidos a los pulmones.
GB0323378D0 (en) * 2003-10-07 2003-11-05 Univ Leicester Therapeutic agent
RU2390529C2 (ru) * 2004-01-07 2010-05-27 Сейкагаку Корпорейшн Производное гиалуроновой кислоты и содержащее его лекарственное средство
GB0623607D0 (en) 2006-11-27 2007-01-03 Haemostatix Ltd Tissue adhesive
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
GB0814302D0 (en) * 2008-08-05 2008-10-01 Coretherapix Slu Compounds and methods
EP2216054A1 (de) 2009-02-06 2010-08-11 ProFibrix BV Biologisch abbaubarer, extravaskulärer Träger
GB0909136D0 (en) 2009-05-28 2009-07-01 Profibrix Bv Dry powder composition
GB0909131D0 (en) 2009-05-28 2009-07-01 Quadrant Drug Delivery Ltd Dry powder fibrin sealant
JP2013516444A (ja) 2010-01-08 2013-05-13 プロフィブリックス ビーブイ 乾燥粉末フィブリンシーラント
NO20110653A1 (no) 2011-05-02 2012-11-05 Spiro Medical As Respirasjonsovervakning
RU2013155713A (ru) 2011-07-06 2015-08-20 Профибрикс Бв Составы для лечения ран

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0494417B1 (de) * 1991-01-10 1996-04-17 Basf Corporation Verfahren zur Vernetzen von Gelatine und Aufnahme eines Materials
GB9221329D0 (en) * 1992-10-10 1992-11-25 Delta Biotechnology Ltd Preparation of further diagnostic agents

Also Published As

Publication number Publication date
FI972546A0 (fi) 1997-06-16
WO1996018388A3 (en) 1996-08-29
BR9510462A (pt) 1998-12-15
ES2191721T3 (es) 2003-09-16
FI972546A7 (fi) 1997-07-04
JPH10510527A (ja) 1998-10-13
DE69529917T2 (de) 2003-12-11
EP0796090A2 (de) 1997-09-24
DK0796090T3 (da) 2003-06-23
AU692019B2 (en) 1998-05-28
NO972554D0 (no) 1997-06-05
CA2207077C (en) 2007-02-06
NZ297072A (en) 1999-03-29
CN1175208A (zh) 1998-03-04
CZ183797A3 (en) 1997-11-12
JP4350165B2 (ja) 2009-10-21
ZA9510702B (en) 1996-12-17
AU4184996A (en) 1996-07-03
MX9704503A (es) 1997-10-31
NO972554L (no) 1997-06-05
PL321018A1 (en) 1997-11-24
PT796090E (pt) 2003-07-31
WO1996018388A2 (en) 1996-06-20
FI972546L (fi) 1997-07-04
ATE234080T1 (de) 2003-03-15
CA2207077A1 (en) 1996-06-20
HUT77369A (hu) 1998-03-30
EP0796090B1 (de) 2003-03-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: QUADRANT DRUG DELIVERY LTD., RUDDINGTON, NOTTINGHA

8339 Ceased/non-payment of the annual fee