DE69527626D1 - Methoden und mittel zur herstellung von hyaluronsäure - Google Patents

Methoden und mittel zur herstellung von hyaluronsäure

Info

Publication number: DE69527626D1
Authority: DE; Germany
Prior art keywords: sup; hyaluronic acid; methods; density; supercapsulated
Prior art date: 1994-05-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69527626T

Other languages

English (en)

Other versions

DE69527626T2 (de

Inventor

Sten Stahl

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

AMO Uppsala AB

Original Assignee

Pharmacia and Upjohn AB

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-05-26

Filing date

1995-05-24

Publication date

2002-09-05

1995-05-24 Application filed by Pharmacia and Upjohn AB filed Critical Pharmacia and Upjohn AB

2002-09-05 Publication of DE69527626D1 publication Critical patent/DE69527626D1/de

2003-02-13 Application granted granted Critical

2003-02-13 Publication of DE69527626T2 publication Critical patent/DE69527626T2/de

2015-05-25 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title abstract 4
229920002674 hyaluronan Polymers 0.000 title abstract 4
229960003160 hyaluronic acid Drugs 0.000 title abstract 4
239000003795 chemical substances by application Substances 0.000 title 1
241000194017 Streptococcus Species 0.000 abstract 2

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/885—Streptococcus

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Tropical Medicine & Parasitology (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DE69527626T 1994-05-26 1995-05-24 Methoden und mittel zur herstellung von hyaluronsäure Expired - Lifetime DE69527626T2 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE9401806A SE9401806D0 (sv)	1994-05-26	1994-05-26	Method and means for the production of hyaluronic acid
PCT/SE1995/000585 WO1995033067A1 (en)	1994-05-26	1995-05-24	Method and means for the production of hyaluronic acid

Publications (2)

Publication Number	Publication Date
DE69527626D1 true DE69527626D1 (de)	2002-09-05
DE69527626T2 DE69527626T2 (de)	2003-02-13

Family

ID=20394129

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69527626T Expired - Lifetime DE69527626T2 (de)	1994-05-26	1995-05-24	Methoden und mittel zur herstellung von hyaluronsäure

Country Status (13)

Country	Link
US (3)	US6090596A (de)
EP (1)	EP0760863B1 (de)
JP (1)	JP3720361B2 (de)
AT (1)	ATE221576T1 (de)
AU (1)	AU699404B2 (de)
CA (1)	CA2191197C (de)
DE (1)	DE69527626T2 (de)
DK (1)	DK0760863T3 (de)
ES (1)	ES2180639T3 (de)
NZ (1)	NZ287583A (de)
PT (1)	PT760863E (de)
SE (1)	SE9401806D0 (de)
WO (1)	WO1995033067A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9401806D0 (sv)	1994-05-26	1994-05-26	Pharmacia Ab	Method and means for the production of hyaluronic acid
US7091008B1 (en)	1994-07-01	2006-08-15	The Board Of Regents Of The University Of Oklahoma	Hyaluronan synthase genes and expression thereof in Bacillus hosts
US6951743B2 (en)	1997-10-31	2005-10-04	University Of Oklahoma Board Of Regents	Hyaluronan synthase genes and expression thereof in bacillus hosts
US6455304B1 (en)	1994-07-01	2002-09-24	The Board Of Regents Of The University Of Oklahoma	Hyaluronate synthase gene and uses thereof
CN101113436B (zh)	1997-10-31	2013-02-06	俄克拉何马大学董事会	透明质酸合酶基因及其应用
KR20010031682A (ko)	1997-10-31	2001-04-16	존 팔머	히알우로난 합성효소 유전자 및 그의 용도
US7223571B2 (en)	1998-04-02	2007-05-29	The Board Of Regents Of The Universtiy Of Oklahoma	Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US6987023B2 (en)	1998-04-02	2006-01-17	The Board Of Regents Of The University Of Oklahoma	DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
US20060188966A1 (en)	1998-04-02	2006-08-24	Deangelis Paul L	Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US7094581B2 (en)	1998-10-26	2006-08-22	The Board Of Regents Of The University Of Oklahoma	Hyaluronan synthases and methods of making and using same
US6610666B1 (en) *	1999-11-08	2003-08-26	Bio-Hyos Ab	Hyaluronan product and process for manufacturing thereof
EP1539193A4 (de) *	2002-07-03	2010-05-05	Pericor Science Inc	Zusammensetzungen von hyaluronsäure und verwendungsverfahren
JP4106361B2 (ja)	2002-08-19	2008-06-25	コーロンインダストリーズインク	ヒアルロン酸産生微生物菌株及び精製ヒアルロン酸の製造方法
KR100472007B1 (ko) *	2002-08-19	2005-03-10	주식회사 코오롱	히아루론산 생산 균주 및 상기 균주를 이용한 히아루론산 생산방법
US20080063677A1 (en) *	2004-03-10	2008-03-13	New Life Resources, Llc	Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US6946551B2 (en)	2003-03-12	2005-09-20	New Life Resources, Llc	Preparation of hyaluronic acid from eggshell membrane
US20040180025A1 (en) *	2003-03-12	2004-09-16	New Life Resources, Llc	Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations
US8580315B2 (en) *	2004-03-10	2013-11-12	Esm Technologies, Llc	Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations
US7002007B2 (en) *	2004-05-28	2006-02-21	Calcigen Corporation	Production of high molecular weight hyaluronates
US8802651B2 (en) *	2004-06-30	2014-08-12	Abbott Medical Optics Inc.	Hyaluronic acid in the enhancement of lens regeneration
JP4948412B2 (ja)	2004-09-23	2012-06-06	バイエル・クロップサイエンス・アーゲー	ヒアルロナンを製造するための方法および手段
EP1640457A1 (de) *	2004-09-23	2006-03-29	Bayer CropScience GmbH	Verfahren und Mittel zur Herstellung von Hyaluronan
EP1772052A1 (de)	2005-10-05	2007-04-11	Bayer CropScience GmbH	Verbesserte Verfahren und Mittel zur Herstellung von Hyaluronan
EA200870204A1 (ru) *	2006-01-27	2009-04-28	Юниверсити Оф Массачусетс	Системы и способы производства биотоплива и связанных с этим материалов
US7674781B2 (en) *	2006-04-28	2010-03-09	Heather Sheardown	Hyaluronic acid-retaining polymers
KR101509139B1 (ko) *	2006-11-23	2015-04-08	주식회사 엘지생명과학	히알루론산의 정제방법
US8609634B2 (en)	2007-05-16	2013-12-17	Mcneil-Ppc, Inc.	Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US9579341B2 (en)	2007-05-16	2017-02-28	Johnson & Johnson Consumer Inc.	Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
KR101322227B1 (ko)	2011-09-30	2013-10-28	일동제약주식회사	스트렙토코커스 디스갈락티애 ｉｄ9103 균주 및 이를 이용한 히알루론산 생산 방법
JP2017112901A (ja)	2015-12-24	2017-06-29	キッコーマン株式会社	高分子ヒアルロン酸の製造方法
JP7444370B2 (ja) *	2017-08-04	2024-03-06	株式会社明治	乳酸菌の培養方法
US11129862B2 (en)	2017-08-30	2021-09-28	Johnson & Johnson Consumer Inc.	Ophthalmic compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4141973A (en) *	1975-10-17	1979-02-27	Biotrics, Inc.	Ultrapure hyaluronic acid and the use thereof
US4517295A (en) *	1983-02-18	1985-05-14	Diagnostic, Inc.	Hyaluronic acid from bacterial culture
NO161573C (no) *	1983-11-25	1989-08-30	Miles Inc	Fremgangsmaate til fremstilling av hyaluronsyre.
US4784990A (en) *	1985-01-18	1988-11-15	Bio-Technology General Corporation	High molecular weight sodium hyaluronate
CA1328841C (en)	1987-06-12	1994-04-26	Karen K. Brown	Method for the microbiological production of non-antigenic hyaluronic acid
JPS6467196A (en) *	1987-09-08	1989-03-13	Yakult Honsha Kk	Production of hyaluronic acid and strain used therefor
JPH07116243B2 (ja) *	1988-12-21	1995-12-13	理研ビタミン株式会社	ヒアルロン酸ビーズの製造法
SE8900422D0 (sv) *	1989-02-08	1989-02-08	Pharmacia Ab	Tvaerbundna hyaluronatgeler samt foerfarande foer framstaellning av dessa
US5015577A (en) *	1989-08-29	1991-05-14	Board Of Regents, The University Of Texas System	DNA encoding hyaluronate synthase
GB9024223D0 (en) *	1990-11-07	1990-12-19	Fermentech Ltd	Production of hyaluronic acid
US5681825A (en)	1993-03-15	1997-10-28	Lindqvist; Bengt	Surgical method
SE9401806D0 (sv) *	1994-05-26	1994-05-26	Pharmacia Ab	Method and means for the production of hyaluronic acid

1994
- 1994-05-26 SE SE9401806A patent/SE9401806D0/xx unknown
1995
- 1995-05-24 EP EP95921198A patent/EP0760863B1/de not_active Expired - Lifetime
- 1995-05-24 PT PT95921198T patent/PT760863E/pt unknown
- 1995-05-24 DK DK95921198T patent/DK0760863T3/da active
- 1995-05-24 WO PCT/SE1995/000585 patent/WO1995033067A1/en active IP Right Grant
- 1995-05-24 AU AU26335/95A patent/AU699404B2/en not_active Expired
- 1995-05-24 AT AT95921198T patent/ATE221576T1/de not_active IP Right Cessation
- 1995-05-24 DE DE69527626T patent/DE69527626T2/de not_active Expired - Lifetime
- 1995-05-24 US US08/737,408 patent/US6090596A/en not_active Expired - Lifetime
- 1995-05-24 CA CA002191197A patent/CA2191197C/en not_active Expired - Lifetime
- 1995-05-24 NZ NZ287583A patent/NZ287583A/en unknown
- 1995-05-24 ES ES95921198T patent/ES2180639T3/es not_active Expired - Lifetime
- 1995-05-24 JP JP50073796A patent/JP3720361B2/ja not_active Expired - Lifetime
2000
- 2000-02-01 US US09/496,149 patent/US6537795B1/en not_active Expired - Lifetime
2003
- 2003-01-29 US US10/353,891 patent/US7323329B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2191197C (en)	2002-01-15
CA2191197A1 (en)	1995-12-07
EP0760863A1 (de)	1997-03-12
AU2633595A (en)	1995-12-21
PT760863E (pt)	2002-11-29
DK0760863T3 (da)	2002-11-25
NZ287583A (en)	1998-02-26
JP3720361B2 (ja)	2005-11-24
US20030134393A1 (en)	2003-07-17
SE9401806D0 (sv)	1994-05-26
AU699404B2 (en)	1998-12-03
WO1995033067A1 (en)	1995-12-07
DE69527626T2 (de)	2003-02-13
EP0760863B1 (de)	2002-07-31
ES2180639T3 (es)	2003-02-16
US6537795B1 (en)	2003-03-25
US6090596A (en)	2000-07-18
ATE221576T1 (de)	2002-08-15
JPH10501128A (ja)	1998-02-03
US7323329B2 (en)	2008-01-29

Publication	Publication Date	Title
DE69527626D1 (de)	2002-09-05	Methoden und mittel zur herstellung von hyaluronsäure
HUP9802538A2 (hu)	1999-02-01	Vektorok és eljárások helyspecifikus rekombináció előidézésére
UA32566C2 (uk)	2001-02-15	Спосіб одержання штаму мікроорганізму, спосіб продукування триптофану
BG101384A (en)	1997-10-31	New pesticide proteins and strains
CA2082152A1 (en)	1991-11-08	Intermediates in the formation of the calicheamicin and esperamicin oligosaccharides
DE60011243D1 (de)	2004-07-08	Verfahren zur herstellung von mit antioxidant gedoptem uhmwpe und daraus hergestelltes implantat
EP2298927A3 (de)	2012-03-21	Methoden zur Behandlung von Krebs und pathogenen Infektionen unter Verwendung von Antigen-präsentierenden Zellen beladen mit RNA
DK0853636T3 (da)	2000-10-30	Podepolymeriseret latexpolymer med en gradientpolymermorfologi og fremgangsmåde til fremstilling deraf
ATE41034T1 (de)	1989-03-15	Herstellung von protein a.
GR3017201T3 (en)	1995-11-30	Procedure for preparing human factor VIII and analogs thereof.
PT81288A (en)	1985-11-01	Process for preparing antibiotic a 40926 complex belonging to the vancomycin class and its pure factors pa,pb,a,b e b0
BG102623A (en)	1999-03-31	New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms
DE3771882D1 (de)	1991-09-12	Glycopeptide antibiotika, ihre herstellung und verwendung und mikroorganismen, die diese produzieren.
DE69132759D1 (de)	2001-11-15	In protein-freiem Medium wachsende Zellen, die die Replication von exogenen Genen steigern
DE3880392D1 (de)	1993-05-27	Verfahren zur herstellung von neuen produkten zur hemmung des wachstums von hefe und pilzen.
ATE229980T1 (de)	2003-01-15	Glycosilierte und nichtglycolisierte bakterizide/die permeabilität erhoehende proteine und methoden zu ihrer herstellung
DE50006334D1 (en)	2004-06-09	Thermoplastische nanocomposites
WO1998031786A3 (en)	1998-11-05	Novel microorganisms
DE68905705D1 (de)	1993-05-06	Sphaerische phosphoraggregate, ihre herstellung und verwendung in roentgenstrahlschirmen.
DE69422928D1 (de)	2000-03-09	Modifizierte maxadilan-protein, dessen herstellung und verwendung, und dem protein kodierende dns
EP1946767A3 (de)	2008-07-30	Autologe T-Zelle-Impfstoffe und -Verfahren
ATE299177T1 (de)	2005-07-15	Milchsäurebakterien und ihre anwendung zur herstellung von hypercholesterolemische aktive produkte
DE3884735D1 (de)	1993-11-11	Material für die fischerei, ausgezeichnet zur verhinderung des anklebens von mikroorganismen,und verfahreen zu dessen herstellung.
ATE254659T1 (de)	2003-12-15	Mikroorganismen, ihre herstellung und verwendung
GR1000639B (el)	1992-09-11	Μεθοδος για την παρασκευη μιας συνθεσεως για την αντιμετωπιση της αμυγδαλιτιδας.

Legal Events

Date	Code	Title	Description
2003-08-28	8364	No opposition during term of opposition
2006-10-12	8327	Change in the person/name/address of the patent owner	Owner name: ADVANCED MEDICAL OPTICS UPPSALA AB, UPPSALA, SE
2011-04-21	8327	Change in the person/name/address of the patent owner	Owner name: AMO UPPSALA AB, UPPSALA, SE