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DE69527507D1 - Transdermal absorbierbare zubereitung - Google Patents

Transdermal absorbierbare zubereitung

Info

Publication number
DE69527507D1
DE69527507D1 DE69527507T DE69527507T DE69527507D1 DE 69527507 D1 DE69527507 D1 DE 69527507D1 DE 69527507 T DE69527507 T DE 69527507T DE 69527507 T DE69527507 T DE 69527507T DE 69527507 D1 DE69527507 D1 DE 69527507D1
Authority
DE
Germany
Prior art keywords
preparation
absorbable preparation
skin penetration
percutaneously absorbable
transdermal absorbable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69527507T
Other languages
English (en)
Other versions
DE69527507T2 (de
Inventor
Kaneto Uekama
Tetsumi Irie
Michio Hara
Yasuhide Horiuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of DE69527507D1 publication Critical patent/DE69527507D1/de
Publication of DE69527507T2 publication Critical patent/DE69527507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69527507T 1994-11-17 1995-11-16 Transdermal absorbierbare zubereitung Expired - Fee Related DE69527507T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28379394 1994-11-17
PCT/JP1995/002350 WO1996015793A1 (en) 1994-11-17 1995-11-16 Percutaneously absorbable preparation

Publications (2)

Publication Number Publication Date
DE69527507D1 true DE69527507D1 (de) 2002-08-29
DE69527507T2 DE69527507T2 (de) 2002-11-07

Family

ID=17670220

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69527507T Expired - Fee Related DE69527507T2 (de) 1994-11-17 1995-11-16 Transdermal absorbierbare zubereitung

Country Status (15)

Country Link
US (1) US5854281A (de)
EP (1) EP0742011B1 (de)
JP (1) JP4024852B2 (de)
KR (1) KR100413202B1 (de)
CN (1) CN1102850C (de)
AT (1) ATE220911T1 (de)
AU (1) AU713461B2 (de)
CA (1) CA2181364A1 (de)
DE (1) DE69527507T2 (de)
ES (1) ES2180658T3 (de)
FI (1) FI962869L (de)
NO (1) NO962972L (de)
PT (1) PT742011E (de)
TW (1) TW413637B (de)
WO (1) WO1996015793A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0925788A4 (de) * 1997-03-13 1999-12-01 Toray Industries Arzneimittel zur behandlung von diabetischen vaskulären verletzungen
US6448251B1 (en) * 1997-11-28 2002-09-10 Peter T. Pugliese Zwitterionic-fatty acid compounds having anti-inflammatory properties
US6114337A (en) * 1998-11-27 2000-09-05 Pugliese; Peter T. Zwitteronic-fatty acid compounds having anti-inflammatory properties
IL140475A0 (en) * 1998-06-25 2002-02-10 Lavipharm Lab Inc A device and method for the treatment of erectile dysfunction
US8119159B2 (en) * 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US7658938B2 (en) * 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
ATE453374T1 (de) * 1999-11-24 2010-01-15 Agile Therapeutics Inc Verbessertes transdermales verabreichungssystem zur empfängnisverhütung und verfahren
JP2004528369A (ja) * 2001-05-03 2004-09-16 アラーガン、インコーポレイテッド 向上した薬物動態特性を有する組成物
WO2002092069A1 (en) 2001-05-11 2002-11-21 Elan Corporation, Plc Permeation enhancers
ES2636943T3 (es) * 2003-05-09 2017-10-10 Toray Industries, Inc. Beraprost y un inhibidor del sistema renina-angiotensina para usar en el tratamiento de enfermedades renales
EP1711170B1 (de) * 2004-01-14 2009-07-29 Lavipharm Laboratories, Inc. Transdermale abgabevorrichtung für dihydropyridin-artige calcium-antagonisten mit 2 fettsäuren
JPWO2006118173A1 (ja) * 2005-04-28 2008-12-18 小野薬品工業株式会社 経皮吸収製剤
WO2007117706A2 (en) 2006-04-07 2007-10-18 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US20070292512A1 (en) * 2006-06-09 2007-12-20 Merrion Research Ii Limited Solid Oral Dosage Form Containing an Enhancer
EP2288369B1 (de) 2008-05-07 2014-07-09 Merrion Research III Limited Zusammensetzungen von gnrh-verwandten verbindungen und herstellungsverfahren
US20130274352A1 (en) * 2009-04-14 2013-10-17 The Regents Of The University Of California Oral Drug Devices and Drug Formulations
AU2010339907A1 (en) 2009-12-16 2012-07-05 Nod Pharmaceuticals, Inc. Compositions and methods for oral drug delivery
US20110142889A1 (en) * 2009-12-16 2011-06-16 Nod Pharmaceuticals, Inc. Compositions and methods for oral drug delivery
WO2011120033A1 (en) 2010-03-26 2011-09-29 Merrion Research Iii Limited Pharmaceutical compositions of selective factor xa inhibitors for oral administration
US8802114B2 (en) 2011-01-07 2014-08-12 Merrion Research Iii Limited Pharmaceutical compositions of iron for oral administration
JP5878715B2 (ja) * 2011-09-22 2016-03-08 久光製薬株式会社 貼付剤
US9457012B2 (en) 2012-03-22 2016-10-04 Teikoku Seiyaku Co., Ltd. Transdermal absorption preparation
JP6444305B2 (ja) * 2013-08-09 2018-12-26 帝國製薬株式会社 ベラプロスト含有貼付剤
EP3250191B1 (de) 2015-01-29 2024-01-17 Novo Nordisk A/S Tabletten mit glp-1-agonisten und magensaftresistentem überzug
US20190343796A1 (en) * 2016-12-28 2019-11-14 Fujifilm Toyama Chemical Co., Ltd. Composition for external use
US20230391809A1 (en) * 2022-06-07 2023-12-07 Biomimetix Jv, Llc Hydrophobic compositions including a hydrophilic active ingredient and methods relating thereto

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58124778A (ja) * 1982-01-20 1983-07-25 Toray Ind Inc ５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体
ZA875317B (en) * 1986-08-01 1988-01-25 Warner-Lambert Company Transdermal compositions
DE3779999T2 (de) * 1986-11-14 1992-12-10 Theratech Inc Erhoehung des penetrationsvermoegens mittels eines aus die zellhuelle veraendernden substanzen und kurzkettigen alkoholen bestehenden binaeren systems.
JPH02503672A (ja) * 1987-06-01 1990-11-01 ワーナー‐ランバート・コンパニー 水性の系における浸透促進剤としての脂肪酸およびその短鎖エステル
US5045553A (en) * 1987-06-24 1991-09-03 Fujisawa Pharmaceutical Company, Ltd. Pharmaceutical composition for percutaneous drug absorption and percutaneous drug absorption promoter
JP2503672B2 (ja) 1989-07-28 1996-06-05 井関農機株式会社 草刈機の刈草収容装置
JPH0737389B2 (ja) * 1989-08-29 1995-04-26 久光製薬株式会社 プロスタグランジンｅ１含有の軟膏剤
JP2838297B2 (ja) * 1989-11-02 1998-12-16 日産化学工業株式会社 コルヒチン含有外用剤
JPH082801B2 (ja) * 1989-11-09 1996-01-17 株式会社資生堂 経皮吸収促進剤及び皮膚外用剤
JP3243564B2 (ja) * 1990-08-20 2002-01-07 リードケミカル株式会社 外用貼付剤
JP3059204B2 (ja) * 1990-10-25 2000-07-04 帝國製薬株式会社 安定なプロスタグランジンｉ▲下１▼類含有皮膚適用組成物
JPH04243827A (ja) * 1991-01-25 1992-08-31 Sumitomo Pharmaceut Co Ltd プロスタグランジン誘導体含有溶解型軟膏剤
DE4124693A1 (de) * 1991-07-22 1993-01-28 Schering Ag Carbacyclinderivate als mittel zur behandlung von vitiligo
DE4124695C2 (de) * 1991-07-22 1994-12-22 Blitstein Willinger Eveline Dr Verwendung von Carbacyclinderivaten zur Behandlung von Psoriasis vulgaris
DE4210165A1 (de) * 1991-07-30 1993-02-04 Schering Ag Transdermale therapeutische systeme
US5403867A (en) * 1992-02-07 1995-04-04 Kaken Pharmaceutical Co., Ltd. Preparation for treating wounds or hemorrhoids
JP3102141B2 (ja) * 1992-05-29 2000-10-23 東レ株式会社 養毛育毛剤
JP3115482B2 (ja) * 1994-01-28 2000-12-04 帝人株式会社 プロスタサイクリン類含有皮膚適用組成物

Also Published As

Publication number Publication date
CA2181364A1 (en) 1996-05-30
EP0742011A4 (de) 1997-08-20
JP4024852B2 (ja) 2007-12-19
FI962869L (fi) 1996-09-16
AU713461B2 (en) 1999-12-02
CN1102850C (zh) 2003-03-12
ES2180658T3 (es) 2003-02-16
KR100413202B1 (ko) 2004-04-13
FI962869A0 (fi) 1996-07-16
WO1996015793A1 (en) 1996-05-30
US5854281A (en) 1998-12-29
EP0742011B1 (de) 2002-07-24
DE69527507T2 (de) 2002-11-07
PT742011E (pt) 2002-10-31
EP0742011A1 (de) 1996-11-13
ATE220911T1 (de) 2002-08-15
TW413637B (en) 2000-12-01
CN1140412A (zh) 1997-01-15
AU3881195A (en) 1996-06-17
NO962972D0 (no) 1996-07-16
NO962972L (no) 1996-09-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee