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DE69516519D1 - Wirkstoff gegen arteriosklerose - Google Patents

Wirkstoff gegen arteriosklerose

Info

Publication number
DE69516519D1
DE69516519D1 DE69516519T DE69516519T DE69516519D1 DE 69516519 D1 DE69516519 D1 DE 69516519D1 DE 69516519 T DE69516519 T DE 69516519T DE 69516519 T DE69516519 T DE 69516519T DE 69516519 D1 DE69516519 D1 DE 69516519D1
Authority
DE
Germany
Prior art keywords
proliferation
smooth muscle
muscle cells
vascular smooth
active against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69516519T
Other languages
English (en)
Other versions
DE69516519T2 (de
Inventor
Hisao Tomioka
Hidefumi Ohsawa
Masao Moroi
T Kawashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tokyo Pharmaceuticals Inc
Original Assignee
Mitsubishi Tokyo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tokyo Pharmaceuticals Inc filed Critical Mitsubishi Tokyo Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69516519D1 publication Critical patent/DE69516519D1/de
Publication of DE69516519T2 publication Critical patent/DE69516519T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
DE69516519T 1994-05-31 1995-02-24 Wirkstoff gegen arteriosklerose Expired - Fee Related DE69516519T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11914694 1994-05-31
PCT/JP1995/000277 WO1995032714A1 (fr) 1994-05-31 1995-02-24 Depresseur de l'arteriosclerose

Publications (2)

Publication Number Publication Date
DE69516519D1 true DE69516519D1 (de) 2000-05-31
DE69516519T2 DE69516519T2 (de) 2000-10-12

Family

ID=14754063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69516519T Expired - Fee Related DE69516519T2 (de) 1994-05-31 1995-02-24 Wirkstoff gegen arteriosklerose

Country Status (8)

Country Link
US (1) US5840741A (de)
EP (1) EP0766963B1 (de)
KR (1) KR970703147A (de)
AT (1) ATE192040T1 (de)
AU (1) AU702727B2 (de)
CA (1) CA2190750A1 (de)
DE (1) DE69516519T2 (de)
WO (1) WO1995032714A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4171303B2 (ja) * 2001-02-26 2008-10-22 田辺三菱製薬株式会社 腎疾患・腎不全の予防剤及び/又は治療剤
US20070225301A1 (en) * 2006-02-13 2007-09-27 Astion Inflammation Aps Treatment of acne and other diseases
KR20090106526A (ko) * 2006-12-18 2009-10-09 카르도스 아베 염증 질환 치료를 위한 새로운 조합
EP2107907B1 (de) * 2006-12-20 2012-02-01 Cardoz AB Kombination von Pemirolast und Ramatroban zur Verwendung bei der Behandlung von entzündlichen Erkrankungen
WO2009007680A2 (en) 2007-07-11 2009-01-15 Cardoz Ab Combinations comprising a mast cell inhibitor and a statin for use in the treatment of inflammatory disorders
WO2009007673A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a ppar gamma agonist
WO2009007679A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a thromboxane a2 antagonist
WO2009007675A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a p2 gamma 12 antagonist
DE102014222804B4 (de) 2014-11-07 2023-12-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung und Verfahren zum Bestimmen einer Wandschubspannung und System zur Erkennung von Arteriosklerose

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH9305A (en) * 1970-05-21 1975-08-18 H Hess Trialkoxy quinazolines
JP3116970B2 (ja) * 1991-06-12 2000-12-11 三菱東京製薬株式会社 ペミロラストカリウムの徐放性製剤

Also Published As

Publication number Publication date
AU702727B2 (en) 1999-03-04
CA2190750A1 (en) 1995-12-07
DE69516519T2 (de) 2000-10-12
KR970703147A (ko) 1997-07-03
WO1995032714A1 (fr) 1995-12-07
US5840741A (en) 1998-11-24
EP0766963A4 (de) 1997-10-29
EP0766963B1 (de) 2000-04-26
ATE192040T1 (de) 2000-05-15
AU1823995A (en) 1995-12-21
EP0766963A1 (de) 1997-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee