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DE69509508D1 - DEVICE AND METHOD FOR ASEPTICALLY MIXING LIQUIDS - Google Patents

DEVICE AND METHOD FOR ASEPTICALLY MIXING LIQUIDS

Info

Publication number
DE69509508D1
DE69509508D1 DE69509508T DE69509508T DE69509508D1 DE 69509508 D1 DE69509508 D1 DE 69509508D1 DE 69509508 T DE69509508 T DE 69509508T DE 69509508 T DE69509508 T DE 69509508T DE 69509508 D1 DE69509508 D1 DE 69509508D1
Authority
DE
Germany
Prior art keywords
container
products
mixing
product
connection devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69509508T
Other languages
German (de)
Other versions
DE69509508T2 (en
Inventor
Lajos Pethoe
Ivan Hakansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMIA Dev AB
Original Assignee
IMIA Dev AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMIA Dev AB filed Critical IMIA Dev AB
Application granted granted Critical
Publication of DE69509508D1 publication Critical patent/DE69509508D1/en
Publication of DE69509508T2 publication Critical patent/DE69509508T2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2058—Connecting means having multiple connecting ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2075—Venting means for external venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2082—Filtering means for gas filtration

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
  • Accessories For Mixers (AREA)

Abstract

The invention relates to an apparatus for mixing aseptically three or more liquid products (51, 53, 55) and includes at least two pointed connection devices (1, 21, 41) which are provided with through-passing flow passageways (3, 4, 24, 25, 43, 44) and are connected in series by means of a connecting line (61) and are intended to be inserted through penetrable closure means (58, 59, 60) of product containers (52, 54, 56). A first of these connection devices (1) functions to place the first container (52) in communication with the surroundings via a sterilizing filter (7), and connects the first container with the second container (54) through the connecting line (61), wherein the product containers are mutually connected together successively by means of respective subsequent connection devices down to the last product container (56) in line in which the final mixture of products, including the product (55), is collected. A subpressure prevails in the last container in line, this subpressure constituting the force by means of which the products are driven through the system. The invention also relates to a connection device (21) and to a system for aseptically mixing three or more liquid products, and also to a method of mixing the products. The invention is primarily intended for application when mixing the liquid components of a preparation for parenteral nutrient supply.
DE69509508T 1994-02-28 1995-02-21 DEVICE AND METHOD FOR ASEPTICALLY MIXING LIQUIDS Expired - Fee Related DE69509508T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9400681A SE501835C2 (en) 1994-02-28 1994-02-28 Apparatus and method for aseptic mixing of three or more liquid products as well as connectors and systems for producing said mixture
PCT/SE1995/000178 WO1995022954A1 (en) 1994-02-28 1995-02-21 A device and a process for aseptic mixing of liquid products

Publications (2)

Publication Number Publication Date
DE69509508D1 true DE69509508D1 (en) 1999-06-10
DE69509508T2 DE69509508T2 (en) 1999-09-02

Family

ID=20393107

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69509508T Expired - Fee Related DE69509508T2 (en) 1994-02-28 1995-02-21 DEVICE AND METHOD FOR ASEPTICALLY MIXING LIQUIDS

Country Status (10)

Country Link
EP (1) EP0750488B1 (en)
CN (1) CN1054279C (en)
AT (1) ATE179589T1 (en)
AU (1) AU1905295A (en)
CA (1) CA2184249A1 (en)
DE (1) DE69509508T2 (en)
HU (1) HUT76713A (en)
PL (1) PL178101B1 (en)
SE (1) SE501835C2 (en)
WO (1) WO1995022954A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI319984B (en) * 2003-06-06 2010-02-01 Sterile combined preparation
JP5062639B2 (en) * 2006-04-24 2012-10-31 ノボ ノルディスク ヘルス ケア アーゲー Transfer system for forming a drug solution from a lyophilized drug
CN101081192B (en) * 2007-07-03 2011-10-05 王建友 Infusion bottle mouth
EP2658502B1 (en) 2010-12-30 2015-07-08 GE Healthcare UK Limited Multi-vial dispensing
EP3672730B1 (en) * 2017-08-24 2022-06-29 Innatoss Laboratories B.V. Liquid handling system and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9001271D0 (en) * 1990-04-06 1990-04-06 Eric Westberg BLOOD PASSE FOR APPLICATION FOR SEPARATION OF BLOOD IN COMPONENTS
US5154716A (en) * 1990-11-06 1992-10-13 Miles Inc. Bottom blood bag separation system
JPH05131018A (en) * 1991-11-11 1993-05-28 Terumo Corp Bag connection body and manufacture thereof

Also Published As

Publication number Publication date
ATE179589T1 (en) 1999-05-15
CN1054279C (en) 2000-07-12
DE69509508T2 (en) 1999-09-02
HUT76713A (en) 1997-10-28
CN1123521A (en) 1996-05-29
WO1995022954A1 (en) 1995-08-31
EP0750488B1 (en) 1999-05-06
AU1905295A (en) 1995-09-11
SE9400681D0 (en) 1994-02-28
PL178101B1 (en) 2000-02-29
EP0750488A1 (en) 1997-01-02
SE9400681L (en) 1995-05-22
HU9602344D0 (en) 1996-10-28
CA2184249A1 (en) 1995-08-31
PL316025A1 (en) 1996-12-23
SE501835C2 (en) 1995-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee