[go: up one dir, main page]

DE69431839D1 - Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden - Google Patents

Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden

Info

Publication number
DE69431839D1
DE69431839D1 DE69431839T DE69431839T DE69431839D1 DE 69431839 D1 DE69431839 D1 DE 69431839D1 DE 69431839 T DE69431839 T DE 69431839T DE 69431839 T DE69431839 T DE 69431839T DE 69431839 D1 DE69431839 D1 DE 69431839D1
Authority
DE
Germany
Prior art keywords
amino
deoxy
synthesising
disaccharides
oligosaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69431839T
Other languages
English (en)
Other versions
DE69431839T2 (de
Inventor
Kurt G I Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glycorex Transplantation (publ) Lund Se AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69431839D1 publication Critical patent/DE69431839D1/de
Publication of DE69431839T2 publication Critical patent/DE69431839T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69431839T 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden Expired - Lifetime DE69431839T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9301677A SE9301677L (sv) 1993-05-14 1993-05-14 Syntesmetod
PCT/SE1994/000461 WO1994029477A1 (en) 1993-05-14 1994-05-17 Method for the synthesis of amino-deoxy-disaccharides and amino-deoxy-oligosaccharides

Publications (2)

Publication Number Publication Date
DE69431839D1 true DE69431839D1 (de) 2003-01-16
DE69431839T2 DE69431839T2 (de) 2003-04-10

Family

ID=20389953

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431839T Expired - Lifetime DE69431839T2 (de) 1993-05-14 1994-05-17 Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden

Country Status (9)

Country Link
US (1) US5856143A (de)
EP (1) EP0698114B1 (de)
JP (1) JP3723208B2 (de)
AT (1) ATE229078T1 (de)
CZ (1) CZ294859B6 (de)
DE (1) DE69431839T2 (de)
SE (1) SE9301677L (de)
SK (1) SK283138B6 (de)
WO (1) WO1994029477A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301270D0 (sv) 1993-04-19 1993-04-17 Biosensor
SE9400034D0 (sv) 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
US5716812A (en) * 1995-12-12 1998-02-10 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides, and the products formed thereby
US6284494B1 (en) 1995-12-12 2001-09-04 The University Of British Columbia Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes
WO1997028173A1 (en) 1996-01-30 1997-08-07 Novartis Ag SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES
WO1997028174A1 (en) * 1996-01-30 1997-08-07 Novartis Ag SIALYL-LEWISa AND SIALYL-LEWISx EPITOPE ANALOGUES
US7014049B2 (en) 1996-12-23 2006-03-21 Glycorex Transplantation Ab Device for bio-affinity material
DE19812156A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung II
DE19812162A1 (de) * 1998-03-20 1999-09-30 Forschungszentrum Juelich Gmbh Nucleotidaktivierte Di- und Oligosaccharide sowie Verfahren zu deren Herstellung I
AU2136201A (en) * 1999-12-10 2001-06-18 National Research Council Of Canada Method for the synthesis of sialylated oligosaccharide donors
US20030096281A1 (en) * 2001-09-14 2003-05-22 Ganesh Venkataraman Methods of making glycomolecules with enhanced activities and uses thereof
EP1534725A2 (de) 2002-05-16 2005-06-01 Glycomimetics, Inc. Verbindungen und verfahren zur inhibierung von selectinvermittelten funktion
EP1763533B1 (de) 2003-11-19 2008-01-09 GlycoMimetics, Inc. Spezifischer antagonist sowohl für e- als auch p-selektine
ES2375979T3 (es) 2005-08-09 2012-03-07 Glycomimetics, Inc. Inhibidores glicomiméticos de la lectina pa-il, lectina pa-iil o ambas lectinas de pseudomonas.
EP2264043B1 (de) 2005-09-02 2017-11-08 GlycoMimetics, Inc. Heterobifunktionelle Pan-Selektin-Inhibitoren
WO2009126556A1 (en) 2008-04-08 2009-10-15 Glycomimetics, Inc. Pan-selectin inhibitor with enhanced pharmacokinetic activity
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
WO2012037034A1 (en) 2010-09-14 2012-03-22 Glycomimetics, Inc. E-selectin antagonists
CN103782168B (zh) 2011-03-12 2016-03-16 动量制药公司 在糖蛋白产品中包含n-乙酰己糖胺的n-聚醣
ES2655443T7 (es) 2011-12-22 2021-03-22 Glycomimetics Inc Compuestos antagonistas de E-selectina
EP2856159A4 (de) 2012-06-01 2016-04-13 Momenta Pharmaceuticals Inc Verfahren im zusammenhang mit denosumab
SI2928476T1 (en) 2012-12-07 2018-06-29 Glycomimetics, Inc. COMPONENTS, INSTALLATIONS AND PROCEDURES OF THE APPLICATION OF E-SELECTINE OF ANTAGONISTS FOR THE MOBILIZATION OF HEMATOPOETIC CELLS
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
EP3058084A4 (de) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylierte glycoproteine
CN107108679B (zh) 2014-12-03 2020-10-23 糖模拟物有限公司 E-选择蛋白和cxcr4趋化因子受体的异双官能抑制剂
CA3009836A1 (en) 2016-01-22 2017-07-27 Glycomimetics, Inc. Glycomimetic inhibitors of pa-il and pa-iil lectins
US11291678B2 (en) 2016-03-02 2022-04-05 Glycomimetics, Inc Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
JP2019524791A (ja) 2016-08-08 2019-09-05 グリコミメティクス， インコーポレイテッド Ｅ−セレクチンの阻害剤もしくはｃｘｃｒ４の阻害剤との、またはｅ−セレクチンおよびｃｘｃｒ４両方のヘテロ二機能性阻害剤とのｔ細胞チェックポイント阻害剤の組み合わせ
US11072625B2 (en) 2016-10-07 2021-07-27 Glycomimetics, Inc. Highly potent multimeric e-selectin antagonists
JP7272956B2 (ja) 2017-03-15 2023-05-12 グリコミメティクス， インコーポレイテッド Ｅ－セレクチンアンタゴニストとしてのガラクトピラノシル－シクロヘキシル誘導体
WO2019108750A1 (en) 2017-11-30 2019-06-06 Glycomimetics, Inc. Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
CN111566117A (zh) 2017-12-29 2020-08-21 糖模拟物有限公司 E-选择蛋白和半乳凝素-3的异双功能抑制剂
CN111867601A (zh) 2018-03-05 2020-10-30 糖模拟物有限公司 用于治疗急性髓系白血病及相关病症的方法
US11845771B2 (en) 2018-12-27 2023-12-19 Glycomimetics, Inc. Heterobifunctional inhibitors of E-selectin and galectin-3

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415665A (en) * 1980-12-12 1983-11-15 Pharmacia Fine Chemicals Ab Method of covalently binding biologically active organic substances to polymeric substances
SE451849B (sv) * 1985-12-11 1987-11-02 Svenska Sockerfabriks Ab Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter
ZA881430B (de) * 1988-03-02 1988-10-28
SE466403B (sv) * 1988-03-24 1992-02-10 Kurt G I Nilsson Saett att syntetisera oligosackarider
SE466521B (sv) * 1988-10-03 1992-02-24 Kurt G I Nilsson Reagens vid analys bestaaende av ett enzym och en annan ligand, vilka aer kovalent bundna till en vattenoloeslig partikel med en diameter paa mindre aen 500 aa
SE465516B (sv) * 1989-08-18 1991-09-23 Kurt G I Nilsson Saett att framstaella en oligosackaridfoerening varvid glykosidas fraan en mollusk anvaendes
JPH04353521A (ja) * 1991-05-30 1992-12-08 Toray Dow Corning Silicone Co Ltd オルガノポリシルセスキオキサンおよびその製造方法
CA2110797C (en) * 1991-06-10 2001-02-20 Andre P. Venot Modified sialyl lewis x compounds
SE9102292L (sv) * 1991-08-06 1993-02-07 Kurt G I Nilsson Enzymatisk metod
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives

Also Published As

Publication number Publication date
ATE229078T1 (de) 2002-12-15
DE69431839T2 (de) 2003-04-10
CZ294859B6 (cs) 2005-04-13
EP0698114B1 (de) 2002-12-04
CZ301895A3 (en) 1996-03-13
SK145095A3 (en) 1996-06-05
US5856143A (en) 1999-01-05
EP0698114A1 (de) 1996-02-28
JP2002502223A (ja) 2002-01-22
SE9301677L (sv) 1994-11-18
SK283138B6 (sk) 2003-03-04
SE9301677D0 (sv) 1993-05-14
JP3723208B2 (ja) 2005-12-07
WO1994029477A1 (en) 1994-12-22

Similar Documents

Publication Publication Date Title
DE69431839D1 (de) Methode zur synthese von amino-deoxy-disacchariden und amino-deoxy-oligosacchariden
ATE222294T1 (de) Verbesserte verfahren zur enzymatischen synthese von oligosacchariden
DE69217491D1 (de) Verfahren zur enzymatischen herstellung von alpha-sialylierten oligosaccharid-glykosiden
GEP19991647B (en) Method for Production of Methyl N-N-(3,3-dimethyl-butil)-L-a-Aspartil-L-Phenilalanin Ester
CA2237849A1 (en) Processes for producing sugar nucleotides and complex carbohydrates
KR950000723A (ko) 비환원성 올리고당질 및 그 제조 방법과 용도
ATE177790T1 (de) Methode zur enzymatischen synthese von kohlenhydraten
DE69425940D1 (de) Enzymatische synthese von ceramiden und hybrid-ceramiden
AU1436097A (en) Sulphamate derivatives of 1,3,5(10)-estratriene derivatives, methods of producing them and pharmaceutical compounds containing them
PT78019B (en) Process for preparing rebeccamycin and of pharmaceutical compositions containing the same
DE60024580D1 (de) Derivatisierte reduzierte malto-oligosaccharide
ATE111108T1 (de) Verfahren zur herstellung von cyclooctaamylose.
ES8206621A1 (es) Procedimiento para la obtencion de isomaltulosa a partir de sacarosa
SE9304316D0 (sv) Aminosyra-konjugat
KR830004414A (ko) 마이코페놀산 유도체의 제조방법
ATE201211T1 (de) Verfahren zur herstellung von disacchariden und sacchariden
ATE227731T1 (de) Verfahren zur gezielten synthese von beta- glycosidisch verknüpften n- acetylglucosaminderivaten
ATE252593T1 (de) Glykosidierung von 4,5-epoxymorphinan-6-olen
EP0676475A4 (de) Verfahren zur herstellung von saccharid.
FR2777281B1 (fr) Procede de synthese du d-laminaribiose
KR930018032A (ko) 복합효소를 이용한 l-오르니친의 제조방법
US4276412A (en) 3-Trehalosamine compounds
KR870007193A (ko) 당전이 스테비오사이드의 제조방법
US4306028A (en) Biologically pure culture of Nocardiopsis trehalosei sp. nov.
KR970042581A (ko) 아카란 황산을 포함하는 달팽이 엑기스

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GLYCOREX TRANSPLANTATION AB (PUBL), LUND, SE