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DE69410005D1 - N-Substituierte Derivate des N-Methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamins und Verfahren zu deren Herstellung - Google Patents

N-Substituierte Derivate des N-Methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamins und Verfahren zu deren Herstellung

Info

Publication number
DE69410005D1
DE69410005D1 DE69410005T DE69410005T DE69410005D1 DE 69410005 D1 DE69410005 D1 DE 69410005D1 DE 69410005 T DE69410005 T DE 69410005T DE 69410005 T DE69410005 T DE 69410005T DE 69410005 D1 DE69410005 D1 DE 69410005D1
Authority
DE
Germany
Prior art keywords
methyl
phenylpropylamine
trifluoromethylphenoxy
substituted derivatives
alkylaril
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69410005T
Other languages
English (en)
Other versions
DE69410005T2 (de
Inventor
Crnic Zdravko Dr
Srecko Kirin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pliva Farmaceutika dd
Original Assignee
Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HR930129A external-priority patent/HRP930129B1/xx
Priority claimed from HR930130A external-priority patent/HRP930130B1/xx
Application filed by Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd filed Critical Pliva Farmaceutska Kemijska Prehrambena I Kozmeticka Industrija dd
Application granted granted Critical
Publication of DE69410005D1 publication Critical patent/DE69410005D1/de
Publication of DE69410005T2 publication Critical patent/DE69410005T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/48—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/48—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69410005T 1993-02-05 1994-02-04 N-Substituierte Derivate des N-Methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamins und Verfahren zu deren Herstellung Expired - Fee Related DE69410005T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR930129A HRP930129B1 (en) 1993-02-05 1993-02-05 N-substituted derivatives of n-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine and procedure for their preparation
HR930130A HRP930130B1 (en) 1993-02-05 1993-02-05 New process for the preparation of n-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine

Publications (2)

Publication Number Publication Date
DE69410005D1 true DE69410005D1 (de) 1998-06-10
DE69410005T2 DE69410005T2 (de) 1998-11-12

Family

ID=26316866

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69410005T Expired - Fee Related DE69410005T2 (de) 1993-02-05 1994-02-04 N-Substituierte Derivate des N-Methyl-3-(p-trifluormethylphenoxy)-3-phenylpropylamins und Verfahren zu deren Herstellung

Country Status (6)

Country Link
US (1) US5618968A (de)
EP (1) EP0617006B1 (de)
AT (1) ATE165810T1 (de)
DE (1) DE69410005T2 (de)
ES (1) ES2118988T3 (de)
SI (1) SI9400049B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2120368B1 (es) * 1996-06-14 1999-07-01 Almirall Prodesfarma Sa Procedimiento de obtencion de n-metil-3-(p-trifluorometilfenoxi)-3-fenilpropilamina y sus sales farmaceuticamente aceptables.
IT1283141B1 (it) * 1996-07-11 1998-04-07 Laporte Organics Francis S P A Procedimento per la preparazione di n-metil-3-(p-trifluorometilfenossi)-3-fenilpropilamina e dei suoi
HU226690B1 (en) * 1996-09-10 2009-06-29 Egis Gyogyszergyar Nyilvanosan Process for producing fluoxetin
US5936124A (en) * 1998-06-22 1999-08-10 Sepacor Inc. Fluoxetine process from benzoylpropionic acid
US6025517A (en) * 1998-08-03 2000-02-15 Sepracor Inc. Fluoxetine process from benzoylacetonitrile
US20030064429A1 (en) * 1999-08-24 2003-04-03 Agouron Pharmaceuticals, Inc. Efficient methods for the preparation of rhinovirus protease inhibitors, key intermediates and a continuous membrane reactor useful for preparing the same
US6355807B1 (en) 1999-08-24 2002-03-12 Agouron Pharmaceuticals, Inc. Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates
US6774243B2 (en) 1999-08-24 2004-08-10 Agouron Pharmaceuticals, Inc. Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates
US6313350B1 (en) 2001-01-31 2001-11-06 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310250B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form A of fluoxetine hydrochloride
US6258853B1 (en) 2001-01-31 2001-07-10 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6310251B1 (en) 2001-01-31 2001-10-30 Grayson Walker Stowell Form a of fluoxetine hydrochloride
US6316672B1 (en) 2001-01-31 2001-11-13 Grayson Walker Stowell Form a of fluoxetine hydrochloride
WO2011145102A1 (en) 2010-05-18 2011-11-24 Arch Pharmalabs Limited A process for the preparation of n-methyl-o-aryloxy-propanamine derivatives and pharmaceutically acceptable salt thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1228209B (it) * 1989-01-10 1991-06-05 Grato Magnone Procedimento per la preparazione di fluoxetina cloridrato.
FI81083C (fi) * 1989-03-03 1990-09-10 Orion Yhtymae Oy Ett foerbaettrat foerfarande foer framstaellning av n-metyl-3-(p-trifluormetylfenoxi)-3-fenylpropylamin hydroklorid.
IL99316A (en) * 1991-08-27 1995-03-15 Teva Pharma Production of fluoxetine and new intermediates

Also Published As

Publication number Publication date
SI9400049A (en) 1994-09-30
ES2118988T3 (es) 1998-10-01
DE69410005T2 (de) 1998-11-12
SI9400049B (en) 2001-06-30
ATE165810T1 (de) 1998-05-15
US5618968A (en) 1997-04-08
EP0617006B1 (de) 1998-05-06
EP0617006A1 (de) 1994-09-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee