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DE69332201D1 - AEROSOL MASS MEASUREMENT METHOD - Google Patents

AEROSOL MASS MEASUREMENT METHOD

Info

Publication number
DE69332201D1
DE69332201D1 DE69332201T DE69332201T DE69332201D1 DE 69332201 D1 DE69332201 D1 DE 69332201D1 DE 69332201 T DE69332201 T DE 69332201T DE 69332201 T DE69332201 T DE 69332201T DE 69332201 D1 DE69332201 D1 DE 69332201D1
Authority
DE
Germany
Prior art keywords
heat loss
mass
measurement method
mass measurement
aerosol mass
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332201T
Other languages
German (de)
Other versions
DE69332201T2 (en
Inventor
Earl Evans
Parker Flowers
Erwin Hockaday
Wayne Loar
Kenneth Proctor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Glaxo Wellcome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Inc filed Critical Glaxo Wellcome Inc
Publication of DE69332201D1 publication Critical patent/DE69332201D1/en
Application granted granted Critical
Publication of DE69332201T2 publication Critical patent/DE69332201T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/68—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by using thermal effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F25/00—Testing or calibration of apparatus for measuring volume, volume flow or liquid level or for metering by volume
    • G01F25/0092—Testing or calibration of apparatus for measuring volume, volume flow or liquid level or for metering by volume for metering by volume

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicinal Preparation (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The present invention comprises a method for measuring the amount, i.e., mass, of a volatile liquid which comprises passing the mass over a heat loss measuring device, calculating the amount of heat loss accompanying the vaporization of the mass and correlating the heat loss to measurement of heat loss of known liquid aerosol mass made with the same device.
DE69332201T 1992-04-21 1993-04-19 AEROSOL MASS MEASUREMENT METHOD Expired - Lifetime DE69332201T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/871,873 US5261538A (en) 1992-04-21 1992-04-21 Aerosol testing method
PCT/US1993/003620 WO1993020956A1 (en) 1992-04-21 1993-04-19 Aerosol testing method

Publications (2)

Publication Number Publication Date
DE69332201D1 true DE69332201D1 (en) 2002-09-19
DE69332201T2 DE69332201T2 (en) 2003-05-28

Family

ID=25358349

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332201T Expired - Lifetime DE69332201T2 (en) 1992-04-21 1993-04-19 AEROSOL MASS MEASUREMENT METHOD

Country Status (9)

Country Link
US (1) US5261538A (en)
EP (1) EP0637270B1 (en)
JP (1) JP3249121B2 (en)
AT (1) ATE222353T1 (en)
AU (1) AU668183B2 (en)
CA (1) CA2134085A1 (en)
DE (1) DE69332201T2 (en)
FI (1) FI944910A0 (en)
WO (1) WO1993020956A1 (en)

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US20040089561A1 (en) * 1999-11-23 2004-05-13 Herman Craig Steven Method and package for storing a pressurized container containing a drug
WO2001064524A2 (en) 2000-03-01 2001-09-07 Glaxo Group Limited Metered dose inhaler
AU2001270074A1 (en) 2000-06-22 2002-01-02 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
GB0016123D0 (en) * 2000-07-01 2000-08-23 Glaxo Group Ltd Valve for aerosol container
US20030207057A1 (en) 2000-09-18 2003-11-06 Britto Ignatius Loy Metered dose inhaler can coated two or more times with fluorocarbon polymers
GB0025092D0 (en) * 2000-10-13 2000-11-29 Glaxo Group Ltd Medicament dispenser
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GB0125380D0 (en) * 2001-10-23 2001-12-12 Glaxo Group Ltd Medicament dispenser
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UY33373A (en) 2010-05-10 2011-12-30 Gilead Sciences Inc ? Bifunctional pyrazolopyridine compounds, their use in therapy and compositions that comprise them ?.
AU2011253203A1 (en) 2010-05-10 2012-11-22 Gilead Sciences, Inc. Bifunctional quinoline derivatives
KR101970837B1 (en) 2010-06-24 2019-04-19 길리애드 사이언시즈, 인코포레이티드 Pyrazolo[1,5-a]pyrimidines as antiviral agents
CA2804840C (en) 2010-07-22 2018-09-11 Gilead Sciences, Inc. Methods and compounds for treating paramyxoviridae virus infections
TW201305185A (en) 2010-09-13 2013-02-01 Gilead Sciences Inc 2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
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KR102109223B1 (en) 2012-05-29 2020-05-11 패리온 사이언스 인코퍼레이티드 Dendrimer like amino amides possessing sodium channel blocker activity for the treatment of dry eye and other mucosal diseases
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US9029382B2 (en) 2012-12-17 2015-05-12 Parion Sciences, Inc. 3,5-diamino-6-chloro-N-(N-(4-phenylbutyl)carbamimidoyl) pyrazine-2-carboxamide compounds
MX379300B (en) 2012-12-17 2025-03-11 Parion Sciences Inc CHLORO-PYRAZINE CARBOXAMIDE DERIVATIVES WITH BLOCKING ACTIVITY ON EPITHELIAL SODIUM CHANNELS.
UA119050C2 (en) 2013-11-11 2019-04-25 Ґілеад Саєнсиз, Інк. PYROL [1.2-f] [1.2.4] TRIASINES USED FOR TREATMENT OF RESPIRATORY-SYNCITAL VIRAL INFECTIONS
TWI678369B (en) 2014-07-28 2019-12-01 美商基利科學股份有限公司 Thieno[3,2-d]pyrimidine, furo[3,2-d]pyrimidine, and pyrrolo[3,2-d]pyrimidines useful for treating respiratory syncitial virus infections
TWI673283B (en) 2014-08-21 2019-10-01 美商基利科學股份有限公司 2'-chloro aminopyrimidinone and pyrimidine dione nucleosides
US10330638B2 (en) 2017-01-16 2019-06-25 Wyatt Technology Corporation Method and apparatus to characterize pressurized liquid sample
PH12022551441A1 (en) 2019-12-24 2023-11-20 Carna Biosciences Inc Diacylglycerol kinase modulating compounds
TWI791193B (en) 2020-02-18 2023-02-01 美商基利科學股份有限公司 Antiviral compounds
AU2021224588B2 (en) 2020-02-18 2024-07-18 Gilead Sciences, Inc. Antiviral compounds
TWI775313B (en) 2020-02-18 2022-08-21 美商基利科學股份有限公司 Antiviral compounds
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JP2024522594A (en) 2021-06-23 2024-06-21 ギリアード サイエンシーズ， インコーポレイテッド Diacylglycerol kinase modulating compounds
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Also Published As

Publication number Publication date
ATE222353T1 (en) 2002-08-15
AU4289493A (en) 1993-11-18
EP0637270A4 (en) 1997-05-28
DE69332201T2 (en) 2003-05-28
FI944910L (en) 1994-10-19
AU668183B2 (en) 1996-04-26
US5261538A (en) 1993-11-16
FI944910A0 (en) 1994-10-19
EP0637270B1 (en) 2002-08-14
JP2000515238A (en) 2000-11-14
EP0637270A1 (en) 1995-02-08
WO1993020956A1 (en) 1993-10-28
CA2134085A1 (en) 1993-10-28
JP3249121B2 (en) 2002-01-21

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