[go: up one dir, main page]

DE69331176D1 - Knochenzement und Verfahren zu seiner Herstellung - Google Patents

Knochenzement und Verfahren zu seiner Herstellung

Info

Publication number
DE69331176D1
DE69331176D1 DE69331176T DE69331176T DE69331176D1 DE 69331176 D1 DE69331176 D1 DE 69331176D1 DE 69331176 T DE69331176 T DE 69331176T DE 69331176 T DE69331176 T DE 69331176T DE 69331176 D1 DE69331176 D1 DE 69331176D1
Authority
DE
Germany
Prior art keywords
manufacture
bone cement
cement
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331176T
Other languages
English (en)
Other versions
DE69331176T2 (de
Inventor
Steve T Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Inc
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE69331176D1 publication Critical patent/DE69331176D1/de
Application granted granted Critical
Publication of DE69331176T2 publication Critical patent/DE69331176T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K9/00Use of pretreated ingredients
    • C08K9/10Encapsulated ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0015Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0089Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44Radioisotopes, radionuclides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622Microcapsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
DE69331176T 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung Expired - Lifetime DE69331176T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/921,030 US5334626A (en) 1992-07-28 1992-07-28 Bone cement composition and method of manufacture

Publications (2)

Publication Number Publication Date
DE69331176D1 true DE69331176D1 (de) 2002-01-03
DE69331176T2 DE69331176T2 (de) 2002-07-11

Family

ID=25444810

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331176T Expired - Lifetime DE69331176T2 (de) 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung

Country Status (6)

Country Link
US (2) US5334626A (de)
EP (1) EP0581387B1 (de)
JP (2) JPH0678987A (de)
AU (1) AU666191B2 (de)
CA (1) CA2098082C (de)
DE (1) DE69331176T2 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080801A (en) * 1990-09-13 2000-06-27 Klaus Draenert Multi-component material and process for its preparation
KR0139235B1 (ko) * 1994-01-29 1998-04-28 조세현 정형외과용 세멘트 비드조성물 및 그의 제조방법
US5578662A (en) * 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US20020032298A1 (en) * 1994-07-22 2002-03-14 Bennett Steven L. Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
CA2223450A1 (en) * 1995-06-06 1996-12-12 Merck & Co., Inc. Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
US5942559A (en) * 1996-08-26 1999-08-24 Ivoclar Ag Dental light-curing opaquer
US5756127A (en) * 1996-10-29 1998-05-26 Wright Medical Technology, Inc. Implantable bioresorbable string of calcium sulfate beads
US5902839A (en) * 1996-12-02 1999-05-11 Northwestern University Bone cement and method of preparation
US6713527B2 (en) 1997-02-07 2004-03-30 Queen's University At Kingston Anaesthetic bone cement
US5847046A (en) * 1997-03-12 1998-12-08 United States Surgical Corporation Biodegradable bone cement
US6309420B1 (en) * 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
US6020396A (en) * 1998-03-13 2000-02-01 The Penn State Research Foundation Bone cement compositions
JP2002539894A (ja) * 1999-03-31 2002-11-26 ザ ブリガム アンド ウィメンズ ホスピタル,インコーポレイテッド 外科用ナノ複合材料およびその製造方法
US7371408B1 (en) * 1999-06-07 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
US6273916B1 (en) * 1999-09-02 2001-08-14 Cook Incorporated Method and apparatus for strengthening vertebral bodies
EP1367960B1 (de) * 2001-01-26 2005-11-02 UAB Research Foundation Knochenzement
US7008433B2 (en) * 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
US20020169066A1 (en) * 2001-04-16 2002-11-14 Cerabio, L.L.C. Dense porous structures for use as bone substitutes
ITVI20010126A1 (it) * 2001-05-30 2002-11-30 Tecres Spa Cemento osseo radiopaco per uso ortopedico nonche' metodo di realizzazione
US7371409B2 (en) 2001-09-06 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
DE60335248D1 (de) * 2002-03-29 2011-01-20 Wright Medical Tech Inc Knochentransplantat-ersatzzusammensetzung
US7291179B2 (en) 2002-06-24 2007-11-06 Wright Medical Technology, Inc. Bone graft substitute composition
US6652887B1 (en) 2002-06-24 2003-11-25 Wright Medical Technology, Inc. Bone graft substitute composition
JP4809605B2 (ja) * 2002-10-28 2011-11-09 タイコ ヘルスケア グループ エルピー 生体吸収性接着剤化合物
US7507257B2 (en) * 2003-02-04 2009-03-24 Wright Medical Technology, Inc. Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects
EP2311408B1 (de) 2003-03-14 2019-02-20 DePuy Spine, Inc. Hydraulische Vorrichtung zur Knochenzementeinspritzung bei perkutaner Vertebroplastie
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
IL166017A0 (en) * 2004-12-28 2006-01-15 Disc O Tech Medical Tech Ltd Materials devices and methods for treating bones
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
WO2005030034A2 (en) 2003-09-26 2005-04-07 Depuy Spine, Inc. Device for delivering viscous material
US7829105B2 (en) 2004-03-02 2010-11-09 Nanotherapeutics, Inc. Compositions for repairing bone
US7621952B2 (en) * 2004-06-07 2009-11-24 Dfine, Inc. Implants and methods for treating bone
US20060095138A1 (en) * 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
CN106963464B (zh) 2004-07-30 2019-11-05 德普伊新特斯产品有限责任公司 外科用具
US20060106459A1 (en) * 2004-08-30 2006-05-18 Csaba Truckai Bone treatment systems and methods
DE102004049121B4 (de) * 2004-10-07 2008-01-10 Heraeus Kulzer Gmbh Antibiotikum-/Antibiotika enthaltender PMMA-Knochenzement
US7250550B2 (en) * 2004-10-22 2007-07-31 Wright Medical Technology, Inc. Synthetic bone substitute material
US8048083B2 (en) * 2004-11-05 2011-11-01 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
IL174347A0 (en) * 2005-07-31 2006-08-20 Disc O Tech Medical Tech Ltd Bone cement and methods of use thereof
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
DE102005040429A1 (de) * 2005-08-25 2007-03-01 Heraeus Kulzer Gmbh Wirkstofffreisetzungssystem und seine Verwendung
US8025903B2 (en) 2005-09-09 2011-09-27 Wright Medical Technology, Inc. Composite bone graft substitute cement and articles produced therefrom
AU2006287478B2 (en) 2005-09-09 2012-02-02 Agnovos Healthcare, Llc Composite bone graft substitute cement and articles produced therefrom
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
WO2007089739A2 (en) * 2006-01-27 2007-08-09 Stryker Corporation Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment
US20070233249A1 (en) * 2006-02-07 2007-10-04 Shadduck John H Methods for treating bone
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
WO2007106256A2 (en) * 2006-03-01 2007-09-20 Poly-Med, Inc. Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement
US8685421B2 (en) 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
US9072808B2 (en) * 2006-07-17 2015-07-07 Syracuse University Multi-solution bone cements and methods of making the same
US8383734B2 (en) * 2006-07-17 2013-02-26 Syracuse University Multi-solution bone cements and methods of making the same
US8575274B2 (en) * 2006-07-17 2013-11-05 Syracuse University Multi-solution bone cements and methods of making the same
WO2008032322A2 (en) * 2006-09-14 2008-03-20 Depuy Spine, Inc. Bone cement and methods of use thereof
AU2011226788B2 (en) * 2006-09-14 2013-07-25 Depuy Spine, Inc. Bone Cement and Methods of Use Thereof
AU2007311451A1 (en) 2006-10-19 2008-04-24 Depuy Spine, Inc. Fluid delivery system
US20100233225A1 (en) * 2007-02-09 2010-09-16 Bingyun Li Method of surface coating devices to incorporate bioactive molecules
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
US7883511B2 (en) * 2007-09-12 2011-02-08 Fernyhough Jeffrey C Method and composition for use in reinforcing bone
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
WO2009073209A1 (en) * 2007-12-06 2009-06-11 Osseon Therapeutics, Inc. Vertebroplasty implant with enhanced interfacial shear strength
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
US9445854B2 (en) * 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
ES2483996T3 (es) * 2008-02-28 2014-08-08 Dfine, Inc. Sistemas y métodos de tratamiento de los huesos
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
EP2361077A4 (de) * 2008-07-11 2012-09-05 Univ Syracuse Multi-lösungs-knochenzemente und herstellungsverfahren dafür
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
US9125671B2 (en) 2010-04-29 2015-09-08 Dfine, Inc. System for use in treatment of vertebral fractures
CA2888241C (en) 2012-10-16 2020-12-29 Surmodics, Inc. Wound packing device and methods
TWI653279B (zh) 2013-09-30 2019-03-11 盧希特國際專業聚合物與樹脂公司 可硬化多部分丙烯酸系組合物
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
CN104906640A (zh) * 2015-06-15 2015-09-16 东华大学 一种可显影的生物降解医用捆扎带及其制备方法
US10478241B2 (en) 2016-10-27 2019-11-19 Merit Medical Systems, Inc. Articulating osteotome with cement delivery channel
US11026744B2 (en) 2016-11-28 2021-06-08 Dfine, Inc. Tumor ablation devices and related methods
WO2018107036A1 (en) 2016-12-09 2018-06-14 Dfine, Inc. Medical devices for treating hard tissues and related methods
WO2018129180A1 (en) 2017-01-06 2018-07-12 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
JP7021836B2 (ja) * 2017-03-31 2022-02-17 三井化学株式会社 硬組織補修用組成物及び硬組織補修用キット
DK3603685T3 (da) * 2017-03-31 2024-11-25 Mitsui Chemicals Inc Sammensætning til reparation af hårdt væv og sæt til reparation af hårdt væv
US11937864B2 (en) 2018-11-08 2024-03-26 Dfine, Inc. Ablation systems with parameter-based modulation and related devices and methods
WO2021055617A1 (en) 2019-09-18 2021-03-25 Merit Medical Systems, Inc. Osteotome with inflatable portion and multiwire articulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3715331A (en) * 1970-05-01 1973-02-06 Coe Labor Monomer soluble x-ray opaque methacrylate particles
US4045403A (en) * 1972-07-19 1977-08-30 General Electric Company Method of compounding thermo-plastic polymeric materials and fillers
US4404327A (en) * 1979-10-31 1983-09-13 Crugnola Aldo M Orthopaedic cement from acrylate polymers
US4341691A (en) * 1980-02-20 1982-07-27 Zimmer, Inc. Low viscosity bone cement
DE3128923A1 (de) * 1981-07-22 1983-02-10 Beiersdorf Ag, 2000 Hamburg Pulvermischung fuer chirurgische zwecke
JPS59500453A (ja) * 1982-03-12 1984-03-22 ユナイテイド ステイツ サ−ジカル コ−ポレイシヨン 高分子アクリル人工器官
US4535485A (en) * 1982-03-12 1985-08-20 Medical Biological Sciences, Inc. Polymeric acrylic prothesis
US4547390A (en) * 1982-03-12 1985-10-15 Medical Biological Sciences, Inc. Process of making implantable prosthesis material of modified polymeric acrylic (PMMA) beads coated with PHEMA and barium sulfate
US4500658A (en) * 1983-06-06 1985-02-19 Austenal International, Inc. Radiopaque acrylic resin
DE3341888A1 (de) * 1983-11-19 1985-05-30 Bayer Ag, 5090 Leverkusen Anorganisch-organische fuellstoffe, verfahren zu deren herstellung sowie deren verwendung in polymerisierbaren massen
KR920006865B1 (ko) * 1984-05-18 1992-08-21 워싱톤 유니버시티 테크놀러지 어소우시에이츠 인코오퍼레이티드 입자나 액적을 피복하는 방법과 장치
GB8524152D0 (en) * 1985-10-01 1985-11-06 Cole Polymers Ltd Bone cement
JPH01501756A (ja) * 1986-11-19 1989-06-22 ラボラトリウム フュー エクスペリメンテル シルージー、フォーチュングスインスティチュート、ダフォス 自己硬化性2成分系粉体液体骨セメントの調製方法および装置
US4837279A (en) * 1988-02-22 1989-06-06 Pfizer Hospital Products Corp, Inc. Bone cement
US5061520A (en) * 1990-10-05 1991-10-29 Kv Pharmaceutical Company Particle enrobing process and apparatus
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer

Also Published As

Publication number Publication date
EP0581387B1 (de) 2001-11-21
EP0581387A1 (de) 1994-02-02
JP3670637B2 (ja) 2005-07-13
DE69331176T2 (de) 2002-07-11
CA2098082A1 (en) 1994-01-29
US5334626A (en) 1994-08-02
JP2003160372A (ja) 2003-06-03
AU666191B2 (en) 1996-02-01
US5512610A (en) 1996-04-30
AU3984093A (en) 1994-02-03
CA2098082C (en) 2004-11-23
JPH0678987A (ja) 1994-03-22

Similar Documents

Publication Publication Date Title
DE69331176D1 (de) Knochenzement und Verfahren zu seiner Herstellung
DE69129746D1 (de) Modifiziertes Polysilazan und Verfahren zu seiner Herstellung
DE69214306D1 (de) Organopentasiloxan und Verfahren zu seiner Herstellung
DE69420383D1 (de) Schwingungsdämpfendes Material und Verfahren zu seiner Herstellung
DE69406502D1 (de) Weiches Seidenpapier und Verfahren zu seiner Herstellung
DE69411632D1 (de) Filtermaterial und Verfahren zu seiner Herstellung
DE59401343D1 (de) Medizinisches pflastermaterial sowie verfahren zu seiner herstellung
DE69225439D1 (de) Verdichter und Verfahren zu seiner Herstellung
ATE238310T1 (de) Kristalline substanz von pivoxilcefditoren und verfahren zu ihrer herstellung
DE69635445T2 (de) Alkalialuminiumhydroxycarbonatzusammensetzung und verfahren zur herstellung
DE69310402D1 (de) Beschichtungszusammensetzung und Verfahren zu ihrer Herstellung
DE69411694D1 (de) Durchsichtiger Gegenstand und Verfahren zu seiner Herstellung
DE69711648D1 (de) Antimikrobielle zusammensetzung und verfahren zu ihrere herstellung
DE69407907D1 (de) Zementprodukte und Verfahren zu deren Herstellung
DE69216692D1 (de) Kondensator und Verfahren zu seiner Herstellung
DE69032447D1 (de) Thermistor und Verfahren zu seiner Herstellung
DE69302810D1 (de) Verbundwerkstoffe und verfahren zu ihrer herstellung
DE69613323D1 (de) Gleitwerkstoff und Verfahren zu seiner Herstellung
DE69301771D1 (de) T-Butyl-R-(-)-4-cyano-3-hydroxybutyrat und Verfahren zu seiner Herstellung
DE69433156D1 (de) Varistor und Verfahren zu seiner Herstellung
DE69406051D1 (de) Synthetisches Quartzglasspulver und Verfahren zu seiner Herstellung
DE69327548D1 (de) Diamantkristall und Verfahren zu seiner Herstellung
DE59606485D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE69404221D1 (de) Bügeleisen und Verfahren zu seiner Herstellung
DE59606489D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZIMMER, INC. (N.D.GES.D. STAATES DELAWARE), WA, US