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DE69327813D1 - Alpha-Glucosyl-Catecholaminderivate, ihre Salze, Herstellung und Verwendung - Google Patents

Alpha-Glucosyl-Catecholaminderivate, ihre Salze, Herstellung und Verwendung

Info

Publication number
DE69327813D1
DE69327813D1 DE69327813T DE69327813T DE69327813D1 DE 69327813 D1 DE69327813 D1 DE 69327813D1 DE 69327813 T DE69327813 T DE 69327813T DE 69327813 T DE69327813 T DE 69327813T DE 69327813 D1 DE69327813 D1 DE 69327813D1
Authority
DE
Germany
Prior art keywords
glucosyl
alpha
salts
production
catecholamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69327813T
Other languages
English (en)
Inventor
Tetsuya Nakada
Michio Kubota
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Application granted granted Critical
Publication of DE69327813D1 publication Critical patent/DE69327813D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69327813T 1992-03-09 1993-03-05 Alpha-Glucosyl-Catecholaminderivate, ihre Salze, Herstellung und Verwendung Expired - Lifetime DE69327813D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10154292A JP3457014B2 (ja) 1992-03-09 1992-03-09 α−グリコシル カテコールアミン類とその製造方法並びに用途

Publications (1)

Publication Number Publication Date
DE69327813D1 true DE69327813D1 (de) 2000-03-16

Family

ID=14303328

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327813T Expired - Lifetime DE69327813D1 (de) 1992-03-09 1993-03-05 Alpha-Glucosyl-Catecholaminderivate, ihre Salze, Herstellung und Verwendung

Country Status (6)

Country Link
US (4) US5380837A (de)
EP (1) EP0564099B1 (de)
JP (1) JP3457014B2 (de)
KR (1) KR930019686A (de)
DE (1) DE69327813D1 (de)
TW (1) TW270120B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3457014B2 (ja) * 1992-03-09 2003-10-14 株式会社林原生物化学研究所 α−グリコシル カテコールアミン類とその製造方法並びに用途
US5710133A (en) * 1993-05-07 1998-01-20 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo α-glycosyl derivative of catecholamine or its salt, and its preparation and uses
ES2159484B1 (es) * 1999-12-22 2002-05-01 Consejo Superior Investigacion Derivados de glicosil-diacil dopamina y sus sales como agentes potenciales de reposicion de dopamina en cerebro y su procedimiento de obtencion.
US20060189547A1 (en) * 2000-04-12 2006-08-24 Christian Samuel T Novel pharmaceutical agents containing carbohydrate moieties and methods of their preparation and use
US7345031B2 (en) * 2000-04-12 2008-03-18 International Medical Innovations, Inc. Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation and use
US9302982B2 (en) 2000-04-12 2016-04-05 Glycon Llc Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation and use
JP2002193990A (ja) * 2000-12-25 2002-07-10 Mitsui Chemicals Inc ハイドロカルコン配糖体および該配糖体を有効成分として配合した化粧料
WO2006056604A1 (en) * 2004-11-25 2006-06-01 Evolva Ag Levodopa glycosyl derivatives, methods of preparation and use
US20060280907A1 (en) * 2005-06-08 2006-12-14 Whitaker Robert H Novel mineral composition
US7651559B2 (en) * 2005-11-04 2010-01-26 Franklin Industrial Minerals Mineral composition
US20070104923A1 (en) * 2005-11-04 2007-05-10 Whitaker Robert H Novel mineral composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4311706A (en) * 1980-01-22 1982-01-19 Interx Research Corporation Novel dopa/dopamine prodrugs
US4337207A (en) * 1980-09-04 1982-06-29 Regents Of The University Of California Biologically active catecholamine derivatives
JP3457014B2 (ja) * 1992-03-09 2003-10-14 株式会社林原生物化学研究所 α−グリコシル カテコールアミン類とその製造方法並びに用途

Also Published As

Publication number Publication date
US5380837A (en) 1995-01-10
JPH05255371A (ja) 1993-10-05
EP0564099B1 (de) 2000-02-09
TW270120B (de) 1996-02-11
JP3457014B2 (ja) 2003-10-14
KR930019686A (ko) 1993-10-18
US5672587A (en) 1997-09-30
EP0564099A1 (de) 1993-10-06
US5618794A (en) 1997-04-08
US5656460A (en) 1997-08-12

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Legal Events

Date Code Title Description
8332 No legal effect for de