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DE69326559D1 - RECOMBINANT METHOD AND HOST FOR THE PRODUCTION OF XYLITOL - Google Patents

RECOMBINANT METHOD AND HOST FOR THE PRODUCTION OF XYLITOL

Info

Publication number
DE69326559D1
DE69326559D1 DE69326559T DE69326559T DE69326559D1 DE 69326559 D1 DE69326559 D1 DE 69326559D1 DE 69326559 T DE69326559 T DE 69326559T DE 69326559 T DE69326559 T DE 69326559T DE 69326559 D1 DE69326559 D1 DE 69326559D1
Authority
DE
Germany
Prior art keywords
xylitol
host
production
recombinant method
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69326559T
Other languages
German (de)
Other versions
DE69326559T2 (en
Inventor
Anu Harkki
Andrey Myasnikov
Juha Apajalahti
Ossi Pastinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xyrofin Oy
Original Assignee
Xyrofin Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xyrofin Oy filed Critical Xyrofin Oy
Application granted granted Critical
Publication of DE69326559D1 publication Critical patent/DE69326559D1/en
Publication of DE69326559T2 publication Critical patent/DE69326559T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel methods for the synthesis of xylitol are described.
DE69326559T 1992-11-05 1993-11-05 RECOMBINANT METHOD AND HOST FOR THE PRODUCTION OF XYLITOL Expired - Lifetime DE69326559T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97332592A 1992-11-05 1992-11-05
PCT/FI1993/000450 WO1994010325A1 (en) 1992-11-05 1993-11-05 Recombinant method and host for manufacture of xylitol

Publications (2)

Publication Number Publication Date
DE69326559D1 true DE69326559D1 (en) 1999-10-28
DE69326559T2 DE69326559T2 (en) 2000-02-10

Family

ID=25520759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326559T Expired - Lifetime DE69326559T2 (en) 1992-11-05 1993-11-05 RECOMBINANT METHOD AND HOST FOR THE PRODUCTION OF XYLITOL

Country Status (15)

Country Link
JP (1) JP3433295B2 (en)
KR (1) KR950704503A (en)
AT (1) ATE184917T1 (en)
AU (1) AU5421594A (en)
BR (1) BR9307391A (en)
CA (1) CA2148622A1 (en)
DE (1) DE69326559T2 (en)
ES (1) ES2139024T3 (en)
FI (1) FI108300B (en)
HU (1) HU219016B (en)
NO (1) NO951747L (en)
NZ (1) NZ257561A (en)
PL (1) PL178040B1 (en)
RU (1) RU2142999C1 (en)
WO (1) WO1994010325A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6723540B1 (en) 1992-11-05 2004-04-20 Xyrofin Oy Manufacture of xylitol using recombinant microbial hosts
WO2001053306A2 (en) * 2000-01-21 2001-07-26 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
GB9514538D0 (en) * 1995-07-15 1995-09-13 Cerestar Holding Bv Process for the production of xylitol
FR2762011B1 (en) * 1997-04-11 1999-06-25 Roquette Freres PROCESS FOR THE PREPARATION OF RIBITOL BY FERMENTATION AND A STRAIN OF MICROORGANISMS USED IN THIS PROCESS
FR2765589B1 (en) * 1997-07-03 1999-09-17 Roquette Freres DNA FRAGMENT COMPRISING THE YAMADAZYMA OHMERI SPECIFIC RIBULOSE REDUCTASE NADPH PROMOTER, VECTOR CONTAINING THE SAME, AND PROTEIN PREPARATION METHOD USING THE SAME
JP3855486B2 (en) * 1997-10-17 2006-12-13 味の素株式会社 Method for producing xylitol
JPH11266888A (en) 1997-10-17 1999-10-05 Ajinomoto Co Inc Production of xylitol
US6335177B1 (en) * 1998-07-08 2002-01-01 Ajinomoto Co., Inc. Microorganisms and method for producing xylitol or d-xylulose
PE20001023A1 (en) * 1998-07-30 2000-10-10 Ajinomoto Kk ACETIC ACID BACTERIA XYLITOL DEHYDROGENASE AND ITS GENE
EP1147196A4 (en) 1998-12-08 2002-10-16 Childrens Hosp Medical Center LOCI POLYMORPHS ALLOWING TO DISTINGUISH ESCHERICHIA COLI 0157: H7 FROM OTHER STRAINS
JP2000210095A (en) * 1999-01-20 2000-08-02 Ajinomoto Co Inc Production of xylitol or d-xylulose
JP2000295994A (en) * 1999-02-09 2000-10-24 Ajinomoto Co Inc Production of xylitol
US6830903B1 (en) 1999-07-23 2004-12-14 Archer-Daniels-Midland Company Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
EP1208205B1 (en) * 1999-07-23 2006-09-27 Archer-Daniels-Midland Company Methods for producing l-amino acids by increasing cellular nadph
US6894199B2 (en) 2001-04-27 2005-05-17 Danisco Sweeteners Oy Process for the production of xylitol
GB2406855A (en) * 2003-02-07 2005-04-13 Danisco Sweeteners Oy Production of xylitol from a carbon source other than xylose and xylulose
US20060110805A1 (en) * 2004-05-19 2006-05-25 Biotechnology Research And Development Corporation Microbial production of xylitol via hexose phosphate and pentose phosphate intermediate
US8088572B2 (en) * 2004-05-20 2012-01-03 Aes Chemunex S.A. Polynucleotides for the detection of Escherichia coli O157:H7 and Escherichia coli O157:NM verotoxin producers
KR101246780B1 (en) * 2010-10-06 2013-03-26 한국과학기술원 Xylitol producing microorganism introduced with arabinose metabolic pathway and production method of xylitol using the same
EP2957640B1 (en) * 2014-06-18 2018-03-14 Roquette Freres Production of xylitol from glucose by a recombinant strain
KR20250008908A (en) * 2022-05-09 2025-01-16 카아길, 인코포레이팃드 Genetically modified yeast and fermentation process for the production of polyols

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009676A1 (en) * 1990-03-26 1991-10-02 Rhein Biotech Proz & Prod Gmbh DNA SEQUENCE, COMPREHENSIVE STRUCTURAL GENERATING FOR XYLOSE REDUCTASE AND / OR XYLITOLDEHYDROGENASE
FI901771A (en) * 1990-04-06 1991-10-07 Valtion Teknillinen ANVAENDNING AV XYLOS HOS HYBRIDJAEST.

Also Published As

Publication number Publication date
RU95113172A (en) 1997-03-27
PL308742A1 (en) 1995-08-21
WO1994010325A1 (en) 1994-05-11
AU5421594A (en) 1994-05-24
HUT72187A (en) 1996-03-28
HU219016B (en) 2001-01-29
RU2142999C1 (en) 1999-12-20
FI108300B (en) 2001-12-31
FI952148A0 (en) 1995-05-04
DE69326559T2 (en) 2000-02-10
HU9501288D0 (en) 1995-06-28
CA2148622A1 (en) 1994-05-11
KR950704503A (en) 1995-11-20
ATE184917T1 (en) 1999-10-15
NO951747D0 (en) 1995-05-04
NZ257561A (en) 1996-09-25
BR9307391A (en) 1999-08-31
NO951747L (en) 1995-07-05
JP3433295B2 (en) 2003-08-04
PL178040B1 (en) 2000-02-29
JPH08505522A (en) 1996-06-18
ES2139024T3 (en) 2000-02-01
FI952148L (en) 1995-07-04

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: XYROFIN OY, ESPOO, FI

8364 No opposition during term of opposition