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DE69233630D1 - Sätze von HIV Sonden für Solution Sandwich Hybridationsverfahren - Google Patents

Sätze von HIV Sonden für Solution Sandwich Hybridationsverfahren

Info

Publication number
DE69233630D1
DE69233630D1 DE69233630T DE69233630T DE69233630D1 DE 69233630 D1 DE69233630 D1 DE 69233630D1 DE 69233630 T DE69233630 T DE 69233630T DE 69233630 T DE69233630 T DE 69233630T DE 69233630 D1 DE69233630 D1 DE 69233630D1
Authority
DE
Germany
Prior art keywords
sets
sandwich hybridization
hybridization procedures
hiv
probes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233630T
Other languages
English (en)
Other versions
DE69233630T2 (de
Inventor
D Irvine
A Kolberg
S Urdea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69233630D1 publication Critical patent/DE69233630D1/de
Application granted granted Critical
Publication of DE69233630T2 publication Critical patent/DE69233630T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • AIDS & HIV (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
DE69233630T 1991-12-23 1992-12-22 Sätze von HIV-Sonden zur Verwendung in Sandwich-Hydridisierungsassays in Lösungsphase Expired - Lifetime DE69233630T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81358391A 1991-12-23 1991-12-23
US813583 1991-12-23
PCT/US1992/011168 WO1993013223A1 (en) 1991-12-23 1992-12-22 Hiv probes for use in solution phase sandwich hybridization assays

Publications (2)

Publication Number Publication Date
DE69233630D1 true DE69233630D1 (de) 2006-07-20
DE69233630T2 DE69233630T2 (de) 2007-05-31

Family

ID=25212818

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233630T Expired - Lifetime DE69233630T2 (de) 1991-12-23 1992-12-22 Sätze von HIV-Sonden zur Verwendung in Sandwich-Hydridisierungsassays in Lösungsphase

Country Status (11)

Country Link
US (1) US6300056B1 (de)
EP (2) EP1752545A3 (de)
JP (5) JP3907201B2 (de)
AT (1) ATE329054T1 (de)
CA (1) CA2124797C (de)
DE (1) DE69233630T2 (de)
DK (1) DK0726962T3 (de)
ES (1) ES2267094T3 (de)
PT (1) PT726962E (de)
TW (1) TW294722B (de)
WO (1) WO1993013223A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
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US5856088A (en) * 1989-07-11 1999-01-05 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
AU686616B2 (en) 1993-03-26 1998-02-12 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5681697A (en) * 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
US6593086B2 (en) 1996-05-20 2003-07-15 Mount Sinai School Of Medicine Of New York University Nucleic acid amplification methods
USRE38442E1 (en) * 1994-06-22 2004-02-24 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
US5876924A (en) * 1994-06-22 1999-03-02 Mount Sinai School Of Medicine Nucleic acid amplification method hybridization signal amplification method (HSAM)
EP0717782A1 (de) * 1994-06-22 1996-06-26 Mount Sinai School Of Medicine Of The City University Of New York Ligation-abhängige amplifizierung zum nachweis von infektösen pathogenen und anormalen genen
US5942391A (en) 1994-06-22 1999-08-24 Mount Sinai School Of Medicine Nucleic acid amplification method: ramification-extension amplification method (RAM)
US5733781A (en) * 1994-07-19 1998-03-31 Gen-Probe Incorporated Oligonucleotides and methods for inhibiting propagation of human immunodeficiency virus
US5599662A (en) * 1995-02-17 1997-02-04 Hoffmann-La Roche Inc. Oliconucleotide primers and probes for the detection of HIV-1
US5780227A (en) * 1995-06-07 1998-07-14 Sheridan; Patrick J. Oligonucleotide probe conjugated to a purified hydrophilic alkaline phosphatase and uses thereof
US5853974A (en) * 1995-06-07 1998-12-29 Chiron Corporation Enhancement of alkaline phosphatase with SDS in chemiluminescent substrates
US6265152B1 (en) 1995-12-22 2001-07-24 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
US6830887B2 (en) 1997-03-18 2004-12-14 Bayer Healthcare Llc Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample
US5962665A (en) 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US6261781B1 (en) 1997-08-05 2001-07-17 Wisconsin Alumni Research Foundation Direct detection and mutation analysis of low copy number nucleic acids
US6013442A (en) * 1997-08-05 2000-01-11 Wisconsin Alumni Res Found Direct quantitation of low copy number RNA
CA2302201A1 (en) * 1997-09-26 1999-04-08 Visible Genetics Inc. Method and kit for evaluation of hiv mutations
US6365346B1 (en) * 1998-02-18 2002-04-02 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
WO2000046403A2 (en) * 1999-02-03 2000-08-10 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OFHEALT H AND HUMAN SERVICES Methods and reagents for molecular detection of hiv-1 groups m, n and o
DE60043789D1 (de) * 1999-07-09 2010-03-18 Gen Probe Inc HIV-1 Detektion mittels Nukleinsäureamplifizierung
WO2001098537A2 (en) * 2000-06-17 2001-12-27 Third Wave Technologies, Inc. Nucleic acid accessible hybridization sites
US20090075256A1 (en) * 2000-06-17 2009-03-19 Third Wave Technologies, Inc. Nucleic Acid Accessible Hybridization Site Identification Using Mass Spectrometry
US6893822B2 (en) 2001-07-19 2005-05-17 Nanogen Recognomics Gmbh Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
US8617816B2 (en) * 2007-03-16 2013-12-31 454 Life Sciences, A Roche Company System and method for detection of HIV drug resistant variants
US20100136516A1 (en) * 2008-12-01 2010-06-03 454 Life Sciences Corporation System and method for detection of HIV integrase variants
WO2011119920A2 (en) 2010-03-25 2011-09-29 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2568289A3 (de) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
KR102062418B1 (ko) 2012-08-31 2020-01-03 도레이 카부시키가이샤 표적 핵산의 검출 방법
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CN108138243A (zh) * 2015-09-18 2018-06-08 西门子医疗保健诊断公司 用于hiv分析的试剂和方法
US10689689B2 (en) * 2015-12-28 2020-06-23 Roche Molecular Systems, Inc. Generic method for the stabilization of specific RNA

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008182A (en) * 1986-01-10 1991-04-16 Cetus Corporation Detection of AIDS associated virus by polymerase chain reaction
AU606043B2 (en) 1985-03-28 1991-01-31 F. Hoffmann-La Roche Ag Detection of viruses by amplification and hybridization
JPS63502477A (ja) 1985-12-03 1988-09-22 エル・ギユ−リイ・エム・ラフアツト 病気診断のための方法、装置および製品
US4868105A (en) 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
FR2600342B1 (fr) 1986-06-19 1989-11-17 Eurobio Lab Procede pour le depistage, chez les individus seropositifs, des sequences d'adn du retrovirus htlv iii-lav et coffret pour sa mise en oeuvre
US5030714A (en) 1986-06-23 1991-07-09 Institut Pasteur Variant of LAV viruses
EP0276302B1 (de) 1986-08-11 1993-04-28 Siska Diagnostics,Inc. Methoden und zusammensetzungen für tests mit nukleinsäuresonden
EP0272098A3 (de) 1986-12-15 1990-06-06 City Of Hope National Medical Center Verfahren zur Vergrösserung und zum Nachweis von RNS-Sequenzen
JP2948823B2 (ja) 1987-01-16 1999-09-13 アンステイテユ・パストウール ヒト免疫不全レトロウィルス(hiv)関連抗原性ペプチド、そのウィルス感染の検出及びワクチンへの使用
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
CA1339351C (en) * 1987-10-15 1997-08-26 Michael S. Urdea Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5030557A (en) 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
EP0326395A2 (de) 1988-01-29 1989-08-02 City Of Hope Verfahren zum Nachweis und zur Identifizierung von bestimmten viralen Sequenzien
JPH03504199A (ja) 1988-05-10 1991-09-19 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー 迅速な核酸検出法
CA2002076A1 (en) 1988-11-21 1990-05-21 Brent A. Burdick Diagnostic kit and method using a solid phase capture means for detecting nucleic acids
CA2026573A1 (en) 1989-02-03 1990-08-04 John B. Findlay Nucleic acid test article and its use to detect a predetermined nucleic acid
DK0806484T3 (da) * 1989-06-02 2006-08-14 Pasteur Institut Syntese af proteiner eller polypeptider kodet af en nucleotidsekvens af HIV-1, HIV-2 eller SIV.
EP0510085B1 (de) * 1990-01-10 1999-09-08 Chiron Diagnostics Corporation Dns-abhängige rns-polymerase-transkripte als reportermoleküle zur signalverstärkung in nukleinsäure-hybridisierungsuntersuchungen
FR2663040B1 (fr) * 1990-06-11 1995-09-15 Bio Merieux Procede de detection d'une sequence nucleotidique selon la technique d'hybridation sandwich.
US5229364A (en) * 1991-03-15 1993-07-20 Francesca Chiodi Polypeptides derived from the human immunodeficiency virus endonuclease protein

Also Published As

Publication number Publication date
TW294722B (de) 1997-01-01
JP2006254924A (ja) 2006-09-28
DK0726962T3 (da) 2006-10-09
PT726962E (pt) 2006-10-31
EP0726962B1 (de) 2006-06-07
US6300056B1 (en) 2001-10-09
EP1752545A2 (de) 2007-02-14
CA2124797C (en) 2004-03-30
JP2003000286A (ja) 2003-01-07
ATE329054T1 (de) 2006-06-15
EP1752545A3 (de) 2007-12-26
EP0726962A4 (de) 1998-05-13
JP2004298197A (ja) 2004-10-28
JP2001069997A (ja) 2001-03-21
JPH07502654A (ja) 1995-03-23
WO1993013223A1 (en) 1993-07-08
ES2267094T3 (es) 2007-03-01
CA2124797A1 (en) 1993-07-08
EP0726962A1 (de) 1996-08-21
JP3907201B2 (ja) 2007-04-18
DE69233630T2 (de) 2007-05-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

R071 Expiry of right

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