DE69232143D1 - Verwendung von Amlexanox zur Herstellung eines Arzneimittels zur Behandlung von aphtösen Ulcera - Google Patents
Verwendung von Amlexanox zur Herstellung eines Arzneimittels zur Behandlung von aphtösen UlceraInfo
- Publication number
- DE69232143D1 DE69232143D1 DE69232143T DE69232143T DE69232143D1 DE 69232143 D1 DE69232143 D1 DE 69232143D1 DE 69232143 T DE69232143 T DE 69232143T DE 69232143 T DE69232143 T DE 69232143T DE 69232143 D1 DE69232143 D1 DE 69232143D1
- Authority
- DE
- Germany
- Prior art keywords
- amlexanox
- manufacture
- alkyl
- treatment
- cyano
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SGRYPYWGNKJSDL-UHFFFAOYSA-N amlexanox Chemical compound NC1=C(C(O)=O)C=C2C(=O)C3=CC(C(C)C)=CC=C3OC2=N1 SGRYPYWGNKJSDL-UHFFFAOYSA-N 0.000 title abstract 4
- 229960003731 amlexanox Drugs 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 208000025865 Ulcer Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 231100000397 ulcer Toxicity 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 208000002399 aphthous stomatitis Diseases 0.000 abstract 1
- 125000005098 aryl alkoxy carbonyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 nitro, hydroxy, carboxyl Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
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- A61K31/12—Ketones
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
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- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Physiology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68234791A | 1991-04-09 | 1991-04-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69232143D1 true DE69232143D1 (de) | 2001-11-22 |
DE69232143T2 DE69232143T2 (de) | 2002-06-06 |
Family
ID=24739298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69232143T Expired - Lifetime DE69232143T2 (de) | 1991-04-09 | 1992-04-09 | Verwendung von Amlexanox zur Herstellung eines Arzneimittels zur Behandlung von aphtösen Ulcera |
Country Status (8)
Country | Link |
---|---|
EP (2) | EP0518798A3 (de) |
JP (1) | JPH0597706A (de) |
AT (1) | ATE206922T1 (de) |
CA (1) | CA2065496C (de) |
DE (1) | DE69232143T2 (de) |
DK (1) | DK0836852T3 (de) |
ES (1) | ES2166043T3 (de) |
PT (1) | PT836852E (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9707934D0 (en) | 1997-04-18 | 1997-06-04 | Danbiosyst Uk | Improved delivery of drugs to mucosal surfaces |
ES2249846T3 (es) | 1997-12-02 | 2006-04-01 | Archimedes Development Limited | Composiciones para administracion nasal. |
US6432415B1 (en) * | 1999-12-17 | 2002-08-13 | Axrix Laboratories, Inc. | Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces |
AR029489A1 (es) | 2000-03-10 | 2003-07-02 | Euro Celtique Sa | Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento |
AR036873A1 (es) | 2001-09-07 | 2004-10-13 | Euro Celtique Sa | Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento |
AR037233A1 (es) | 2001-09-07 | 2004-11-03 | Euro Celtique Sa | Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento |
GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
GB0414803D0 (en) * | 2004-07-01 | 2004-08-04 | Glaxo Group Ltd | Composition |
WO2014071203A1 (en) * | 2012-11-02 | 2014-05-08 | University Of Kentucky Research Foundation | Sustained release of topical anesthetics |
EP3544570B1 (de) * | 2016-12-27 | 2020-12-02 | Colgate-Palmolive Company | Mundpflegeprodukte und verfahren für deren verwendung und herstellung |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4255576A (en) * | 1977-03-08 | 1981-03-10 | Takeda Chemical Industries, Ltd. | 1-Azaxanthone derivatives |
US4228173A (en) * | 1978-08-15 | 1980-10-14 | Fisons Limited | Thiopyrano-benzopyrans, compositions and method of use thereof |
IT1232252B (it) * | 1989-02-22 | 1992-01-28 | Rotta Research Lab | Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione |
EP0416925A3 (en) * | 1989-09-07 | 1991-09-25 | Glaxo Group Limited | Use of 4-hydroxy-alpha 1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedimethanol or its salts in the treatment of allergy and inflammation |
-
1992
- 1992-04-08 JP JP4087185A patent/JPH0597706A/ja active Pending
- 1992-04-09 DK DK97202524T patent/DK0836852T3/da active
- 1992-04-09 AT AT97202524T patent/ATE206922T1/de not_active IP Right Cessation
- 1992-04-09 ES ES97202524T patent/ES2166043T3/es not_active Expired - Lifetime
- 1992-04-09 CA CA002065496A patent/CA2065496C/en not_active Expired - Lifetime
- 1992-04-09 EP EP9292470014A patent/EP0518798A3/en not_active Withdrawn
- 1992-04-09 EP EP97202524A patent/EP0836852B1/de not_active Expired - Lifetime
- 1992-04-09 PT PT97202524T patent/PT836852E/pt unknown
- 1992-04-09 DE DE69232143T patent/DE69232143T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0836852A1 (de) | 1998-04-22 |
ATE206922T1 (de) | 2001-11-15 |
DK0836852T3 (da) | 2001-11-19 |
EP0518798A2 (de) | 1992-12-16 |
EP0836852B1 (de) | 2001-10-17 |
CA2065496A1 (en) | 1992-10-10 |
CA2065496C (en) | 2003-03-25 |
DE69232143T2 (de) | 2002-06-06 |
ES2166043T3 (es) | 2002-04-01 |
JPH0597706A (ja) | 1993-04-20 |
EP0518798A3 (en) | 1994-12-07 |
PT836852E (pt) | 2002-02-28 |
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Owner name: ACCESS PHARMACEUTICALS,INC.(N. D. GES. D. STAA, US |
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8327 | Change in the person/name/address of the patent owner |
Owner name: ULURU INC. (N. D. GES. D. STAATES NEVADA ), AD, US |