DE69230796D1 - Zusammensetzung enthaltend eine glutathion erhöhende substanz und vitamine zur behandlung von aids, krebs und diabetes - Google Patents
Zusammensetzung enthaltend eine glutathion erhöhende substanz und vitamine zur behandlung von aids, krebs und diabetesInfo
- Publication number
- DE69230796D1 DE69230796D1 DE69230796T DE69230796T DE69230796D1 DE 69230796 D1 DE69230796 D1 DE 69230796D1 DE 69230796 T DE69230796 T DE 69230796T DE 69230796 T DE69230796 T DE 69230796T DE 69230796 D1 DE69230796 D1 DE 69230796D1
- Authority
- DE
- Germany
- Prior art keywords
- glutathion
- vitamins
- diabetes
- cancer
- composition containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 208000030507 AIDS Diseases 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title 1
- 229960003180 glutathione Drugs 0.000 title 1
- 235000003969 glutathione Nutrition 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A61K31/51—Thiamines, e.g. vitamin B1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/30—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/063—Glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/711,530 US5977073A (en) | 1991-06-06 | 1991-06-06 | Nutrient composition for treatment of immune disorders |
| PCT/US1992/004653 WO1992021368A1 (en) | 1991-06-06 | 1992-06-04 | Composition and method for disease treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69230796D1 true DE69230796D1 (de) | 2000-04-20 |
Family
ID=24858455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69230796T Expired - Lifetime DE69230796D1 (de) | 1991-06-06 | 1992-06-04 | Zusammensetzung enthaltend eine glutathion erhöhende substanz und vitamine zur behandlung von aids, krebs und diabetes |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5977073A (de) |
| EP (1) | EP0604433B1 (de) |
| AU (1) | AU2187992A (de) |
| DE (1) | DE69230796D1 (de) |
| WO (1) | WO1992021368A1 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2947044B2 (ja) * | 1993-01-27 | 1999-09-13 | 味の素株式会社 | 免疫不全症候群治療の補助療法剤 |
| US5686436A (en) | 1993-05-13 | 1997-11-11 | Hiv Diagnostics, Inc. | Multi-faceted method to repress reproduction of latent viruses in humans and animals |
| US5886000A (en) * | 1994-01-26 | 1999-03-23 | Nissui Pharmaceutical Co., Ltd, | Anti-HIV agent |
| GB2289406A (en) * | 1994-04-15 | 1995-11-22 | Britannia Health Products Ltd | Vitamin, betacarotene and zinc composition for sperm health |
| DE4437403A1 (de) * | 1994-10-19 | 1996-04-25 | Mann Gerhard Chem Pharm Fab | Antioxidativum |
| US5627152A (en) * | 1995-01-18 | 1997-05-06 | Telluride Pharmaceutical Corporation | Method for increasing bodyweight |
| US6750209B1 (en) * | 1995-09-12 | 2004-06-15 | Kansas University Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
| RU2089179C1 (ru) * | 1995-12-14 | 1997-09-10 | Закрытое акционерное общество "ВАМ" | Стимулятор эндогенной продукции цитокинов и гепопоэтических факторов и способ его использования |
| ATE214936T1 (de) * | 1995-12-14 | 2002-04-15 | Novelos Therapeutics Inc | Oxidiertes glutathion als mittel zur verbesserung der endogenen produktion von cytokinen und haematopoietischen faktoren |
| US6251857B1 (en) | 1995-12-14 | 2001-06-26 | Novelos Therapeutics, Inc. | Cytokine and hemopoietic factor endogenous production enhancer and methods of use thereof |
| US6369106B1 (en) * | 1996-12-26 | 2002-04-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Treatment of ischemic brain injuries with brain targeted anti oxidant compounds |
| AU2387997A (en) * | 1997-04-18 | 1998-11-13 | Klinge Pharma Gmbh | Stabilized medicaments containing cysteinyl derivatives |
| DE19721470A1 (de) * | 1997-05-22 | 1998-12-03 | Ralf Dr Henkel | Die Verwendung von N-Acetyl-L-Cystein zur Behandlung von männlicher Unfruchtbarkeit |
| FR2766712B1 (fr) * | 1997-08-01 | 1999-10-22 | Aguettant Lab | Composition de preference solution antioxydante et medicaments en faisant application |
| US7371415B1 (en) | 1998-04-03 | 2008-05-13 | The Daily Wellness Company | Method and composition for improving sexual fitness |
| AU3221599A (en) * | 1998-04-03 | 1999-10-25 | Daily Wellness Company, The | Compositions comprising l-arginine, ginseng and gingko biloba for enhancing blood circulation |
| US6251868B1 (en) | 1998-04-30 | 2001-06-26 | Teijin Limited | Method for treating a human immunodeficiency virus infection |
| US20070142267A1 (en) * | 1998-11-23 | 2007-06-21 | Novelos Therapeutics, Inc. | Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells |
| RU2144374C1 (ru) * | 1998-11-23 | 2000-01-20 | Закрытое акционерное общество "ВАМ" | Способ получения композита окисленного глутатиона с cis-диаминодихлорплатиной и фармацевтических композиций на его основе, регулирующих метаболизм, пролиферацию, дифференцировку и механизмы апоптоза нормальных и трансформированных клеток |
| US6642259B1 (en) | 1999-05-07 | 2003-11-04 | Trustees Of Tufts College | Immune stimulating dietary supplement and method of use thereof |
| FR2794122B1 (fr) * | 1999-05-27 | 2001-09-07 | Centre Nat Rech Scient | Nouveaux antioxydants, procedes de preparation et utilisations |
| IT1317938B1 (it) * | 2000-11-17 | 2003-07-15 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento di alterazioni delmetabolismo lipidico, delle forme allergiche e per attivare le difese |
| US6497885B2 (en) * | 2000-12-22 | 2002-12-24 | The Daily Wellness Company | Method and composition for improving fertility health in female and male animals and humans |
| US6490345B2 (en) * | 2001-01-17 | 2002-12-03 | Sbc Technology Resources, Inc. | Dialing plan service including outgoing call screening, remote tie-line routing, call data reporting and billing |
| CN100378087C (zh) * | 2001-08-24 | 2008-04-02 | 马蒂亚斯·拉特 | 抗坏血酸化合物，合成方法及其应用 |
| WO2004033484A2 (en) * | 2002-10-11 | 2004-04-22 | University Of Virginia Patent Foundation | Use of stable glutamine derivatives to improve drug absorption |
| KR100925516B1 (ko) * | 2002-10-31 | 2009-11-05 | 박래옥 | 아연 및 ｌ-아르기닌을 함유한 항암용 조성물 |
| GB2396809A (en) * | 2003-01-03 | 2004-07-07 | Vitabiotics Ltd | Composition for the treatment of HIV and AIDS |
| JP2006516633A (ja) * | 2003-01-29 | 2006-07-06 | エクシトン−エクシマー ゲーエムベーハー | Ｈｉｖ−１及びｈｉｖ−２を処置するための治療用組成物 |
| WO2004093824A2 (en) * | 2003-04-08 | 2004-11-04 | Fairfield Clinical Trials, Llc | Peri-operative and peri-procedure nutritional supplementation |
| CA2531582A1 (en) * | 2003-06-06 | 2005-01-06 | Pro-Health, Inc. | Composition and method for treating upper abdominal pain and cramping |
| AU2003266526A1 (en) * | 2003-09-17 | 2005-04-11 | Kaname Kawasugi | Medicinal composition |
| US20050202521A1 (en) * | 2004-03-10 | 2005-09-15 | Albert Crum | Methods of assessing the need for and the effectiveness of therapy with antioxidants |
| US7727961B2 (en) * | 2004-04-30 | 2010-06-01 | Tokai Bussan Co., Ltd. | Antioxidant constituents |
| US8202546B2 (en) | 2005-08-04 | 2012-06-19 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| US8263137B2 (en) | 2005-08-04 | 2012-09-11 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US7998500B2 (en) | 2005-08-04 | 2011-08-16 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US7901710B2 (en) | 2005-08-04 | 2011-03-08 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| CN100360125C (zh) * | 2005-10-10 | 2008-01-09 | 浙江杭州鑫富药业股份有限公司 | 一种含谷氨酰胺的复方组合物及其制药用途 |
| IL172896A0 (en) * | 2005-12-29 | 2006-06-11 | Yeda Res & Dev | Cxcr4 inhibition |
| CA2714200C (en) | 2008-02-05 | 2017-10-17 | Kyowa Hakko Bio Co., Ltd. | Method for improving storage stability of glutathione |
| JP5499714B2 (ja) * | 2008-02-15 | 2014-05-21 | 味の素株式会社 | 腸管免疫賦活剤 |
| US20110064828A1 (en) * | 2009-09-11 | 2011-03-17 | Novelos Therapeutics, Incorporated | Treatment of metastatic tumors and other conditions |
| RU2482868C1 (ru) * | 2011-12-30 | 2013-05-27 | Общество С Ограниченной Ответственностью "Ива Фарм" | Средство для лечения диабета, фармацевтическая композиция и способ лечения заболеваний |
| RU2482869C1 (ru) * | 2011-12-30 | 2013-05-27 | Общество С Ограниченной Ответственностью "Ива Фарм" | Гемостимулирующее средство, фармацевтическая композиция и способ стимулирования гемопоэза |
| RU2522547C1 (ru) * | 2012-11-12 | 2014-07-20 | Федеральное государственное бюджетное учреждение "Научно-исследовательский институт онкологии имени Н.Н. Петрова" Министерства здравоохранения Российской Федерации | Фармакологическая геропротекторная композиция и способ ее получения |
| JOP20190146A1 (ar) | 2016-12-19 | 2019-06-18 | Axcella Health Inc | تركيبات حمض أميني وطرق لمعالجة أمراض الكبد |
| MA49906A (fr) | 2017-08-14 | 2020-06-24 | Axcella Health Inc | Acides aminés à chaîne ramifiée pour le traitement d'une maladie du foie |
| JP2021527670A (ja) | 2018-06-20 | 2021-10-14 | アクセラ・ヘルス・インコーポレイテッドＡｘｃｅｌｌａ Ｈｅａｌｔｈ Ｉｎｃ． | 筋肉中の脂肪浸潤の治療のための組成物及び方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4466978A (en) * | 1981-12-10 | 1984-08-21 | Graham John Naylor | Bodyweight reducing method |
| IT1176983B (it) * | 1984-10-16 | 1987-08-26 | Zambon Spa | Dipeptidi ad attivita' farmacologica |
| US4710489A (en) * | 1985-04-22 | 1987-12-01 | Cornell Research Foundation, Inc. | Glutathione delivery system |
| US4927808A (en) * | 1986-07-07 | 1990-05-22 | Teijin Limited | γ-L-glutamyl-L-cysteine ethyl ester and pharmaceutical compositions containing the same as an effective ingredient |
| ES2036553T3 (es) * | 1986-10-07 | 1993-06-01 | Boehringer Mannheim Italia S.P.A. | Composiciones farmaceuticas que tienen actividad antineoplastica. |
| US4968671A (en) * | 1987-11-26 | 1990-11-06 | Yamanouchi Pharmaceutical Co., Ltd. | Therapeutic agents for ischemic heart diseases |
| US5102871A (en) * | 1989-04-24 | 1992-04-07 | Kyowa Hakko Kogyo Co., Ltd. | Nutrient composition |
| WO1991002535A1 (en) * | 1989-08-11 | 1991-03-07 | Basil, Inc. | Cancer prevention composition and method |
-
1991
- 1991-06-06 US US07/711,530 patent/US5977073A/en not_active Expired - Lifetime
-
1992
- 1992-06-04 WO PCT/US1992/004653 patent/WO1992021368A1/en active IP Right Grant
- 1992-06-04 EP EP92913917A patent/EP0604433B1/de not_active Expired - Lifetime
- 1992-06-04 AU AU21879/92A patent/AU2187992A/en not_active Abandoned
- 1992-06-04 DE DE69230796T patent/DE69230796D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2187992A (en) | 1993-01-08 |
| EP0604433B1 (de) | 2000-03-15 |
| WO1992021368A1 (en) | 1992-12-10 |
| EP0604433A4 (de) | 1994-10-12 |
| US5977073A (en) | 1999-11-02 |
| EP0604433A1 (de) | 1994-07-06 |
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