DE69229572D1 - Gliazellen-aktivierender Faktor und dessen Herstellung - Google Patents
Gliazellen-aktivierender Faktor und dessen HerstellungInfo
- Publication number
- DE69229572D1 DE69229572D1 DE69229572T DE69229572T DE69229572D1 DE 69229572 D1 DE69229572 D1 DE 69229572D1 DE 69229572 T DE69229572 T DE 69229572T DE 69229572 T DE69229572 T DE 69229572T DE 69229572 D1 DE69229572 D1 DE 69229572D1
- Authority
- DE
- Germany
- Prior art keywords
- activating factor
- glia activating
- glial cell
- glia
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 210000004498 neuroglial cell Anatomy 0.000 title abstract 2
- 230000003213 activating effect Effects 0.000 title 1
- 102100037665 Fibroblast growth factor 9 Human genes 0.000 abstract 6
- 108090000367 Fibroblast growth factor 9 Proteins 0.000 abstract 6
- 101000993347 Gallus gallus Ciliary neurotrophic factor Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2086091 | 1991-02-14 | ||
JP22445491 | 1991-09-04 | ||
JP00339992A JP3385040B2 (ja) | 1991-02-14 | 1992-01-10 | グリア活性化因子およびその製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69229572D1 true DE69229572D1 (de) | 1999-08-19 |
DE69229572T2 DE69229572T2 (de) | 1999-11-11 |
Family
ID=27275805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69229572T Expired - Lifetime DE69229572T2 (de) | 1991-02-14 | 1992-02-13 | Gliazellen-aktivierender Faktor und dessen Herstellung |
Country Status (6)
Country | Link |
---|---|
US (2) | US5512460A (de) |
EP (1) | EP0503297B1 (de) |
JP (1) | JP3385040B2 (de) |
AT (1) | ATE182174T1 (de) |
CA (1) | CA2061148C (de) |
DE (1) | DE69229572T2 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840836A (en) * | 1989-02-17 | 1998-11-24 | Bayer Corporation | Pancreatic islet cell antigens obtained by molecular cloning |
US6811989B1 (en) * | 1989-02-17 | 2004-11-02 | Bayer Corporation | Pancreatic islet cell antigens obtained by molecular cloning |
EP0585631A1 (de) * | 1992-08-05 | 1994-03-09 | Takeda Chemical Industries, Ltd. | Blutplättchen vermehrendes Agens |
EP0608546A3 (en) * | 1992-12-22 | 1995-09-27 | Takeda Chemical Industries Ltd | Glia activating factor (gaf), antibodies against it and their uses. |
CA2115522A1 (en) * | 1993-02-12 | 1994-08-13 | Takeda Pharmaceutical Company Limited | Hst-2 mutein, dna coding for the same and preparation thereof |
US5922572A (en) | 1994-01-25 | 1999-07-13 | Human Genome Sciences, Inc. | Polynucleotides encoding haemopoietic maturation factor |
US6447783B1 (en) * | 1995-06-12 | 2002-09-10 | Yeda Research And Development Co., Ltd. | Compositions comprising FGF9 and use thereof for stimulating cartilage and bone repair |
US5731284A (en) * | 1995-09-28 | 1998-03-24 | Amgen Inc. | Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product |
WO1998029547A1 (en) * | 1996-12-31 | 1998-07-09 | The Rockefeller University | Modulators of radial glia-astrocyte differentiation and transformation, and diagnostic and therapeutic uses thereof |
WO1999013074A1 (fr) * | 1997-09-08 | 1999-03-18 | Taisho Pharmaceutical Co., Ltd. | Proteine activant des fonctions de cellules nerveuses |
US20010006939A1 (en) * | 1997-10-03 | 2001-07-05 | Ralph W. Niven | Secretory leukocyte protease inhibitor dry powder pharmaceutical compositions |
US7056885B1 (en) * | 1999-07-27 | 2006-06-06 | Curagen Corporation | Fibroblast growth factor and nucleic acids encoding same |
US20020058036A1 (en) * | 1999-07-27 | 2002-05-16 | Michael Jeffers | Novel fibroblast growth factor and nucleic acids encoding same |
US7291483B2 (en) | 1999-07-27 | 2007-11-06 | Curagen Corporation | FGF-CX polynucleotide sequences and methods of producing same |
IL139380A0 (en) * | 2000-10-31 | 2001-11-25 | Prochon Biotech Ltd | Active variants of fibroblast growth factor |
US6982250B2 (en) | 2000-11-06 | 2006-01-03 | Curagen Corporation | Methods of prevention and treatment of inflammatory bowel disease |
IL149562A0 (en) | 2002-05-09 | 2002-11-10 | Prochon Ltd | Fgf variants and methods for use thereof |
US7067123B2 (en) * | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
WO2007035778A2 (en) | 2005-09-19 | 2007-03-29 | Histogenics Corporation | Cell-support matrix and a method for preparation thereof |
CA2664921A1 (en) | 2006-09-28 | 2008-04-03 | Hepacore Ltd. | N-terminal fgf variants having increased receptor selectivity and uses thereof |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
US20090054984A1 (en) | 2007-08-20 | 2009-02-26 | Histogenics Corporation | Method For Use Of A Double-Structured Tissue Implant For Treatment Of Tissue Defects |
US8685107B2 (en) | 2007-07-03 | 2014-04-01 | Histogenics Corporation | Double-structured tissue implant and a method for preparation and use thereof |
WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
WO2012038953A2 (en) | 2010-09-21 | 2012-03-29 | Hepacore Ltd. | Fgf-18 truncated variants having increased receptor specificity and uses thereof |
WO2012140650A2 (en) | 2011-04-12 | 2012-10-18 | Hepacore Ltd. | Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
US20210395678A1 (en) | 2018-11-08 | 2021-12-23 | Integriculture Inc. | Animal cell growth promoter, culture medium for animal cell culture, and animal cell culture apparatus |
-
1992
- 1992-01-10 JP JP00339992A patent/JP3385040B2/ja not_active Expired - Lifetime
- 1992-02-13 DE DE69229572T patent/DE69229572T2/de not_active Expired - Lifetime
- 1992-02-13 EP EP92102385A patent/EP0503297B1/de not_active Expired - Lifetime
- 1992-02-13 CA CA002061148A patent/CA2061148C/en not_active Expired - Fee Related
- 1992-02-13 AT AT92102385T patent/ATE182174T1/de active
-
1994
- 1994-11-17 US US08/340,820 patent/US5512460A/en not_active Expired - Lifetime
-
1996
- 1996-01-24 US US08/593,535 patent/US5622928A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0503297A1 (de) | 1992-09-16 |
ATE182174T1 (de) | 1999-07-15 |
DE69229572T2 (de) | 1999-11-11 |
JPH05301893A (ja) | 1993-11-16 |
JP3385040B2 (ja) | 2003-03-10 |
CA2061148A1 (en) | 1992-08-15 |
US5512460A (en) | 1996-04-30 |
CA2061148C (en) | 2004-08-24 |
EP0503297B1 (de) | 1999-07-14 |
US5622928A (en) | 1997-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP |