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DE69226522D1 - Herstellung eines medikaments zur behandlung der drogenabhängigkeit - Google Patents

Herstellung eines medikaments zur behandlung der drogenabhängigkeit

Info

Publication number
DE69226522D1
DE69226522D1 DE69226522T DE69226522T DE69226522D1 DE 69226522 D1 DE69226522 D1 DE 69226522D1 DE 69226522 T DE69226522 T DE 69226522T DE 69226522 T DE69226522 T DE 69226522T DE 69226522 D1 DE69226522 D1 DE 69226522D1
Authority
DE
Germany
Prior art keywords
alkyl
hydrogen
hydroxy
medicine
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69226522T
Other languages
English (en)
Other versions
DE69226522T2 (de
Inventor
Jens Kristian Perregaard
Brenda Costall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of DE69226522D1 publication Critical patent/DE69226522D1/de
Application granted granted Critical
Publication of DE69226522T2 publication Critical patent/DE69226522T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Apparatuses And Processes For Manufacturing Resistors (AREA)
  • Disintegrating Or Milling (AREA)
DE69226522T 1991-03-01 1992-02-28 Herstellung eines medikaments zur behandlung der drogenabhängigkeit Expired - Fee Related DE69226522T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK036391A DK36391D0 (da) 1991-03-01 1991-03-01 Anvendelse af piperidylsubstituerede indolderivater til behandling af stofmisbrug
PCT/DK1992/000062 WO1992015302A1 (en) 1991-03-01 1992-02-28 Treatment of addiction to drugs and substances of abuse

Publications (2)

Publication Number Publication Date
DE69226522D1 true DE69226522D1 (de) 1998-09-10
DE69226522T2 DE69226522T2 (de) 1999-01-07

Family

ID=8092675

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226522T Expired - Fee Related DE69226522T2 (de) 1991-03-01 1992-02-28 Herstellung eines medikaments zur behandlung der drogenabhängigkeit

Country Status (17)

Country Link
US (1) US5462948A (de)
EP (1) EP0575430B1 (de)
JP (1) JP3332233B2 (de)
KR (1) KR0181740B1 (de)
AT (1) ATE169218T1 (de)
AU (1) AU661476B2 (de)
CA (1) CA2105384C (de)
DE (1) DE69226522T2 (de)
DK (2) DK36391D0 (de)
HK (1) HK1009253A1 (de)
IE (1) IE920571A1 (de)
IL (1) IL101101A (de)
NO (1) NO304350B1 (de)
NZ (1) NZ241801A (de)
PH (1) PH30084A (de)
WO (1) WO1992015302A1 (de)
ZA (1) ZA921463B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
US5824684A (en) * 1997-02-21 1998-10-20 Synapse Pharmaceuticals International, Inc. Method for treating drug and alcohol addiction
US6489341B1 (en) 1999-06-02 2002-12-03 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using sertindole derivatives
CA2606550C (en) * 2005-04-30 2014-05-27 Boehringer Ingelheim International Gmbh Piperidine-substituted indoles
US20070212412A1 (en) * 2005-09-08 2007-09-13 H. Lundbeck A/S Stable solid formulation of sertindole
TW200821296A (en) * 2006-06-01 2008-05-16 Lundbeck & Co As H Use of sertindole for the preventive treatment of suicidal behaviour

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4999382A (en) * 1988-10-26 1991-03-12 Massachusetts Institute Of Technology Compositions for treating tobacco withdrawal symptoms and methods for their use

Also Published As

Publication number Publication date
DK0575430T3 (da) 1999-05-10
EP0575430B1 (de) 1998-08-05
PH30084A (en) 1996-12-27
NZ241801A (en) 1997-05-26
CA2105384C (en) 2000-09-12
CA2105384A1 (en) 1992-09-02
NO304350B1 (no) 1998-12-07
KR930702977A (ko) 1993-11-29
KR0181740B1 (ko) 1999-05-01
HK1009253A1 (en) 1999-08-13
AU1370692A (en) 1992-10-06
IL101101A (en) 1996-03-31
ZA921463B (en) 1992-11-25
JPH06505021A (ja) 1994-06-09
NO933090D0 (no) 1993-08-31
NO933090L (no) 1993-08-31
DK36391D0 (da) 1991-03-01
IL101101A0 (en) 1992-11-15
JP3332233B2 (ja) 2002-10-07
ATE169218T1 (de) 1998-08-15
EP0575430A1 (de) 1993-12-29
IE920571A1 (en) 1992-09-09
DE69226522T2 (de) 1999-01-07
US5462948A (en) 1995-10-31
AU661476B2 (en) 1995-07-27
WO1992015302A1 (en) 1992-09-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee