DE69221826D1 - Aufgetragene Mikrokugeln - Google Patents
Aufgetragene MikrokugelnInfo
- Publication number
- DE69221826D1 DE69221826D1 DE69221826T DE69221826T DE69221826D1 DE 69221826 D1 DE69221826 D1 DE 69221826D1 DE 69221826 T DE69221826 T DE 69221826T DE 69221826 T DE69221826 T DE 69221826T DE 69221826 D1 DE69221826 D1 DE 69221826D1
- Authority
- DE
- Germany
- Prior art keywords
- layers
- multiplicity
- microspheres
- covalent bonds
- species
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000004005 microsphere Substances 0.000 title abstract 4
- 239000010410 layer Substances 0.000 abstract 7
- 239000000203 mixture Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000002356 single layer Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/28016—Particle form
- B01J20/28019—Spherical, ellipsoidal or cylindrical
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
- B01J20/28004—Sorbent size or size distribution, e.g. particle size
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3257—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3289—Coatings involving more than one layer of same or different nature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3295—Coatings made of particles, nanoparticles, fibers, nanofibers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
- B01J20/3297—Coatings in the shape of a sheet
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/16—Organic material
- B01J39/17—Organic material containing also inorganic materials, e.g. inert material coated with an ion-exchange resin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J47/00—Ion-exchange processes in general; Apparatus therefor
- B01J47/016—Modification or after-treatment of ion-exchangers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL10010591A IL100105A (en) | 1991-11-20 | 1991-11-20 | Supported microspheres |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69221826D1 true DE69221826D1 (de) | 1997-10-02 |
DE69221826T2 DE69221826T2 (de) | 1998-01-02 |
Family
ID=11063080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69221826T Expired - Fee Related DE69221826T2 (de) | 1991-11-20 | 1992-11-19 | Aufgetragene Mikrokugeln |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0544450B1 (de) |
JP (1) | JPH05262672A (de) |
AT (1) | ATE157283T1 (de) |
CA (1) | CA2083296A1 (de) |
DE (1) | DE69221826T2 (de) |
IL (1) | IL100105A (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4312970A1 (de) * | 1993-04-21 | 1994-10-27 | Juergen Dr Schrezenmeir | Mikrokapsel sowie Verfahren und Vorrichtung zu ihrer Herstellung |
US5653875A (en) * | 1994-02-04 | 1997-08-05 | Supelco, Inc. | Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices |
US5633085A (en) * | 1994-06-10 | 1997-05-27 | Potters Industries Inc. | Durable composite particle and method of making same |
US6133436A (en) * | 1996-11-06 | 2000-10-17 | Sequenom, Inc. | Beads bound to a solid support and to nucleic acids |
DE10038124B4 (de) * | 2000-08-04 | 2006-05-11 | Infineon Technologies Ag | Verwendung einer mehrwandigen Nanoröhre auf einem Substrat und als elektronisches Bauelement |
EP2055727A1 (de) * | 2007-10-30 | 2009-05-06 | Corning Incorporated | Leistungsfähige Nanopartikelimmobilisierungsoberfläche |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3795313A (en) * | 1970-05-22 | 1974-03-05 | Du Pont | Chromatographic packing with chemically bonded organic stationary phases |
US4070283A (en) * | 1976-12-08 | 1978-01-24 | E. I. Du Pont De Nemours And Company | Controlled surface porosity particles and a method for their production |
US4111838A (en) * | 1977-09-09 | 1978-09-05 | Eastman Kodak Company | Composition for chromatography |
US4252644A (en) * | 1979-05-25 | 1981-02-24 | The Dow Chemical Company | High performance ion exchange composition and the removal and separation of ions therewith |
DE3130924A1 (de) * | 1981-08-05 | 1983-02-17 | Röhm GmbH, 6100 Darmstadt | Oberflaechenreiche systeme zur fixierung von nucleophile gruppen enthaltenden substraten |
DE68900216D1 (de) * | 1988-06-07 | 1991-09-26 | Rohm & Haas | Ionenaustauscherzusammenstellungen fuer die ionenaustauschchromatographie. |
FR2635019B1 (fr) * | 1988-08-02 | 1992-06-12 | Centre Nat Rech Scient | Materiau capable de fixer les substances biologiques, et ses applications notamment comme support de chromatographie d'affinite |
CA1331254C (en) * | 1989-02-27 | 1994-08-02 | Victor Berber Barretto | Ion-exchange composition employing resin attachment to dispersant and method for forming the same |
-
1991
- 1991-11-20 IL IL10010591A patent/IL100105A/en not_active IP Right Cessation
-
1992
- 1992-11-19 AT AT92310555T patent/ATE157283T1/de active
- 1992-11-19 CA CA002083296A patent/CA2083296A1/en not_active Abandoned
- 1992-11-19 DE DE69221826T patent/DE69221826T2/de not_active Expired - Fee Related
- 1992-11-19 EP EP92310555A patent/EP0544450B1/de not_active Expired - Lifetime
- 1992-11-20 JP JP4333805A patent/JPH05262672A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL100105A0 (en) | 1992-08-18 |
CA2083296A1 (en) | 1993-05-21 |
ATE157283T1 (de) | 1997-09-15 |
JPH05262672A (ja) | 1993-10-12 |
IL100105A (en) | 1996-01-19 |
DE69221826T2 (de) | 1998-01-02 |
EP0544450A1 (de) | 1993-06-02 |
EP0544450B1 (de) | 1997-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA199800369A1 (ru) | Способ переноса гена в клетки-мишени с помощью ретровируса | |
DE3586838D1 (de) | Kieseltraeger. | |
ATE150176T1 (de) | Chromatographisches material | |
DE59204608D1 (de) | Aufzeichnungsträger zur Aufnahme von farbgebenden Stoffen. | |
AU8011294A (en) | Fluorescence energy transfer and intramolecular energy transfer in particles using novel compounds | |
NO166836C (no) | Fremgangsmaate for behandling av et organtransplantat. | |
CA2206602A1 (en) | Sequential delivery of purified biological and chemical reagents | |
ES2031138T3 (es) | Nuevos compuestos lipido-proteina y articulos y procedimientos para su preparacion. | |
NO992167D0 (no) | Preparater og fremgangsmÕter for immobilisering av nukleinsyrer til faste bµrere | |
ATE142340T1 (de) | Universalbindefilm | |
AU585253B2 (en) | Carrier material for use in immune determinations | |
DE68918217D1 (de) | Familie von modifizierten Antikörpern mit hoher Affinität zur Behandlung von Krebs. | |
DE69417184D1 (de) | Transparente, leitfähige Beschichtungszusammensetzung, und transparenter, antistatischer Formkörper | |
ES2176347T3 (es) | Modulacion de la respuesta inmune. | |
CA2137655A1 (en) | Sensor for optical assay | |
DE69221826D1 (de) | Aufgetragene Mikrokugeln | |
AU6969187A (en) | Composition of mixture of 1gG and 1gM type antibodies | |
EP1944321A3 (de) | Verfahren und Verbindungen zur Bestimmung der Reinheit von chemisch synthetisierten Nukleinsäuren | |
AU568857B2 (en) | Polymerisable composition containing inorganic material | |
AU5983786A (en) | Shaped articles, which are provided with coatings, for the binding of substances having a bioaffinity, a process for their preparation, and their use | |
JPS5663845A (en) | Inorganic substance product having surface layer rendered hydrophilic and its manufacture | |
DE3580542D1 (de) | Chromatographische trennungsprozesse an polypeptidtraegermaterial. | |
AU8259087A (en) | Purified appetite-regulating substances of biological origin their antibodies, immunocomplexes of the appetite-regulating substances formed with the antibodies and processes for preparing same | |
ATE66235T1 (de) | Peptidderivate und deren verwendung als substrate zur quantitativen bestimmung von enzymen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |