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DE69206460D1 - Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen. - Google Patents

Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen.

Info

Publication number
DE69206460D1
DE69206460D1 DE69206460T DE69206460T DE69206460D1 DE 69206460 D1 DE69206460 D1 DE 69206460D1 DE 69206460 T DE69206460 T DE 69206460T DE 69206460 T DE69206460 T DE 69206460T DE 69206460 D1 DE69206460 D1 DE 69206460D1
Authority
DE
Germany
Prior art keywords
oxindole
carboxamide derivatives
pharmaceutical preparations
preparations containing
containing injectable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69206460T
Other languages
English (en)
Other versions
DE69206460T2 (de
Inventor
Walter Fries
Carl Joerg Pfitzner
Guenther Dr Pfaff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MACK CHEM PHARM
Original Assignee
MACK CHEM PHARM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MACK CHEM PHARM filed Critical MACK CHEM PHARM
Priority to DE69206460T priority Critical patent/DE69206460T2/de
Application granted granted Critical
Publication of DE69206460D1 publication Critical patent/DE69206460D1/de
Publication of DE69206460T2 publication Critical patent/DE69206460T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69206460T 1991-04-08 1992-04-02 Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen. Expired - Fee Related DE69206460T2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE69206460T DE69206460T2 (de) 1991-04-08 1992-04-02 Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4111306A DE4111306C2 (de) 1991-04-08 1991-04-08 Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
DE69206460T DE69206460T2 (de) 1991-04-08 1992-04-02 Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen.

Publications (2)

Publication Number Publication Date
DE69206460D1 true DE69206460D1 (de) 1996-01-18
DE69206460T2 DE69206460T2 (de) 1996-04-25

Family

ID=6429052

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4111306A Expired - Fee Related DE4111306C2 (de) 1991-04-08 1991-04-08 Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
DE69206460T Expired - Fee Related DE69206460T2 (de) 1991-04-08 1992-04-02 Injizierbare 2-Oxindol-1-carboxamidderivate enthaltende Arzneizubereitungen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4111306A Expired - Fee Related DE4111306C2 (de) 1991-04-08 1991-04-08 Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind

Country Status (7)

Country Link
EP (1) EP0508311B1 (de)
JP (1) JPH05112528A (de)
AT (1) ATE131049T1 (de)
DE (2) DE4111306C2 (de)
DK (1) DK0508311T3 (de)
ES (1) ES2082260T3 (de)
GR (1) GR3019127T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2122236T3 (es) * 1993-01-22 1998-12-16 Pfizer Sal de lisina de la 6-cloro-5-fluoro-3-(2-tenoil)-2-oxindol-1-carboxamida.
US5298522A (en) * 1993-01-22 1994-03-29 Pfizer Inc. 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
JP4130700B2 (ja) * 1996-02-26 2008-08-06 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗腫瘍剤含有組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function

Also Published As

Publication number Publication date
DE4111306A1 (de) 1992-10-15
GR3019127T3 (en) 1996-05-31
DE69206460T2 (de) 1996-04-25
EP0508311B1 (de) 1995-12-06
ATE131049T1 (de) 1995-12-15
DK0508311T3 (da) 1996-03-18
JPH05112528A (ja) 1993-05-07
EP0508311A1 (de) 1992-10-14
ES2082260T3 (es) 1996-03-16
DE4111306C2 (de) 1994-06-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee