[go: up one dir, main page]

DE69204639D1 - Verwendung von Modafinil zur Herstellung eines antiischämischen Arzneimittels. - Google Patents

Verwendung von Modafinil zur Herstellung eines antiischämischen Arzneimittels.

Info

Publication number
DE69204639D1
DE69204639D1 DE69204639T DE69204639T DE69204639D1 DE 69204639 D1 DE69204639 D1 DE 69204639D1 DE 69204639 T DE69204639 T DE 69204639T DE 69204639 T DE69204639 T DE 69204639T DE 69204639 D1 DE69204639 D1 DE 69204639D1
Authority
DE
Germany
Prior art keywords
modafinil
manufacture
ischemic drug
ischemic
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69204639T
Other languages
English (en)
Other versions
DE69204639T2 (de
Inventor
00 00 Fr 00
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of DE69204639D1 publication Critical patent/DE69204639D1/de
Publication of DE69204639T2 publication Critical patent/DE69204639T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/065—Diphenyl-substituted acyclic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69204639T 1991-12-13 1992-12-11 Verwendung von Modafinil zur Herstellung eines antiischämischen Arzneimittels. Expired - Lifetime DE69204639T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9115534A FR2684875B1 (fr) 1991-12-13 1991-12-13 Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique.

Publications (2)

Publication Number Publication Date
DE69204639D1 true DE69204639D1 (de) 1995-10-12
DE69204639T2 DE69204639T2 (de) 1996-04-04

Family

ID=9420051

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69204639T Expired - Lifetime DE69204639T2 (de) 1991-12-13 1992-12-11 Verwendung von Modafinil zur Herstellung eines antiischämischen Arzneimittels.

Country Status (12)

Country Link
US (1) US5391576A (de)
EP (1) EP0547952B1 (de)
JP (1) JPH0825873B2 (de)
KR (1) KR100252390B1 (de)
AT (1) ATE127342T1 (de)
AU (1) AU656642B2 (de)
DE (1) DE69204639T2 (de)
DK (1) DK0547952T3 (de)
FR (1) FR2684875B1 (de)
HU (2) HU216193B (de)
TW (1) TW244335B (de)
UA (1) UA27231C2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2697162B1 (fr) * 1992-10-23 1995-01-13 Lafon Labor Utilisation du modafinil pour la fabrication d'un médicament pour le traitement de l'incontinence urinaire et des troubles sphinctériens urétro vésicaux.
FR2706767B1 (de) * 1993-06-22 1995-09-08 Lafon Labor
FR2708201B1 (fr) * 1993-06-30 1995-10-20 Lafon Labor Utilisation de dérivés d'acétamide pour la fabrication de médicaments.
US5618845A (en) * 1994-10-06 1997-04-08 Cephalon, Inc. Acetamide derivative having defined particle size
DE19943983A1 (de) * 1999-09-14 2001-03-15 Joseph Clasen Verwendung von Modafinil zur Herstellung eines plastizitätsfördernden Arzneimittels
US20010034373A1 (en) * 2000-02-09 2001-10-25 Matthew Miller Low dose modafinil for enhancement of cognitive function
US6492396B2 (en) 2000-05-16 2002-12-10 Cephalon, Inc. Substituted thioacetamides
CN100584322C (zh) * 2000-10-11 2010-01-27 赛福伦公司 包含莫达非尼化合物的组合物
US7704975B2 (en) * 2000-12-19 2010-04-27 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7141555B2 (en) * 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
MXPA03010705A (es) * 2001-05-25 2004-05-27 Cephalon Inc Formulaciones farmaceuticas solidas que comprenden modafinil.
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040048931A1 (en) 2002-07-12 2004-03-11 Craig Heacock Modafinil pharmaceutical compositions
US6992219B2 (en) 2002-08-09 2006-01-31 Cephalon France Modafinil polymorphic forms
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
IL153098A0 (en) * 2002-11-26 2003-06-24 Chemagis Ltd Pharmaceutical compositions containing modafinil
WO2004075841A2 (en) * 2003-02-24 2004-09-10 Mallinckrodt Inc. Process for preparing benzhydrylthioacetamide
US20040253308A1 (en) * 2003-04-29 2004-12-16 Barr Laboratories, Inc. Surface-treated modafinil particles
AR045423A1 (es) * 2003-05-13 2005-10-26 Cephalon Inc Combinaciones de analiticos y antidepresivos
US7368591B2 (en) 2003-09-19 2008-05-06 Cephalon France Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
US7119214B2 (en) * 2004-04-13 2006-10-10 Cephalon France Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives
EP1586560A1 (de) * 2004-04-13 2005-10-19 Cephalon, Inc. Thio-substituierte Arylmethansulfinyl-Derivate
US7314875B2 (en) * 2004-04-13 2008-01-01 Cephalon, Inc. Tricyclic aromatic and bis-phenyl sulfinyl derivatives
US7297817B2 (en) * 2004-04-13 2007-11-20 Cephalon France Thio-substituted arylmethanesulfinyl derivatives
US20060024370A1 (en) 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20080181966A1 (en) * 2006-10-18 2008-07-31 Cephalon, Inc. Modafinil pharmaceutical compositions
US20090325999A1 (en) * 2008-06-27 2009-12-31 Jie Du Personalized pharmaceutical kits, packaging and compositions for the treatment of allergic conditions
EP2238973A1 (de) 2009-04-07 2010-10-13 Cephalon France Lyophilisierte Präparate von Proteasominhibitoren
KR101414831B1 (ko) * 2011-10-25 2014-07-04 이화여자대학교 산학협력단 모다피닐 또는 이의 유도체를 포함하는 ＫＣａ3.1 채널 매개 질환 치료용 조성물
KR101345860B1 (ko) * 2011-10-25 2013-12-30 이화여자대학교 산학협력단 모다피닐 또는 이의 유도체를 포함하는 혈관질환 치료용 조성물
WO2013062316A2 (ko) * 2011-10-25 2013-05-02 이화여자대학교 산학협력단 모다피닐 또는 이의 유도체를 포함하는 혈관질환 또는 ＫＣａ3.1 채널 매개 질환 치료용 조성물
WO2015030283A1 (ko) 2013-08-30 2015-03-05 주식회사 녹십자에이치에스 진세노사이드 성분이 증가된 가공인삼분말 또는 가공인삼추출물을 함유하는 암 관련 피로의 예방 및 치료용 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
FR2663225B1 (fr) * 1990-06-14 1994-11-04 Lafon Labor Nouvelle utilisation du modafinil.

Also Published As

Publication number Publication date
DK0547952T3 (da) 1996-01-22
EP0547952A1 (de) 1993-06-23
DE69204639T2 (de) 1996-04-04
TW244335B (de) 1995-04-01
HU9203921D0 (en) 1993-03-29
ATE127342T1 (de) 1995-09-15
FR2684875B1 (fr) 1995-05-24
HUT67784A (en) 1995-04-28
EP0547952B1 (de) 1995-09-06
HU216193B (hu) 1999-05-28
FR2684875A1 (fr) 1993-06-18
KR100252390B1 (ko) 2000-05-01
JPH0665070A (ja) 1994-03-08
AU656642B2 (en) 1995-02-09
US5391576A (en) 1995-02-21
AU3008092A (en) 1993-06-17
UA27231C2 (uk) 2000-08-15
KR930012022A (ko) 1993-07-20
JPH0825873B2 (ja) 1996-03-13

Similar Documents

Publication Publication Date Title
DE69204639D1 (de) Verwendung von Modafinil zur Herstellung eines antiischämischen Arzneimittels.
DE68922726D1 (de) Medizinisches material und verfahren zur herstellung.
DE69020075D1 (de) Katheterführung und Führungsdrahts zur Durchführung eines schnellen Katheteraustausches.
ATE150643T1 (de) Analgetisches mittel und dessen verwendung
DE59006880D1 (de) Gerät zur Herstellung von Formkörpern und Verwendung desselben zur Herstellung von Inlays, Onlays, und Kronen in der Zahnmedizin.
DE10199020I2 (de) Galanthamin oder dessen Analoge zur Behandlung derAlzheimerschen Krankheit.
ATE213411T1 (de) Verwendung von phenserin zur herstellung von medikamenten zur behandlung von kognitiven störungen
DE59200764D1 (de) Verfahren und Einrichtung zur Aufbereitung oder Herstellung von Kunststoffen.
DE69212620D1 (de) Verwendung von Glycosaminoglycanen zur Behandlung von diabetischer Nephropathie und diabetischer Neuropathie
ATE141505T1 (de) Verwendung von 3-guanidinopropionsäure zur herstellung eines medikaments zur behandlung und prävention von fettsucht
ATE191849T1 (de) Verwendung von (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidinacetamid zur herstellung eines medikaments zur behandlung von angst
DE59101776D1 (de) Verfahren zur Herstellung klein dimensionierter Formkörper mit hohem Etofibrat-Gehalt und kontrollierter Wirkstoff-Freisetzung, deren Verwendung und daraus bestehende oral verabreichbare Applikationsformen.
DE69233725D1 (de) Verwendung von DNA oder RNA zur Herstellung eines Medikaments zur Behandlung von Tumoren
DE69431199D1 (de) Melatonin-Derivate zur Verwendung in der Behandlung von Schlafstörungen
DE68916266D1 (de) Methode zur Herstellung und Stabilisierung von Halosilanen mit Acrylfunktionen.
DE69232911D1 (de) Verwendung eines polyhydroxybenzamids oder dessen Derivat zur Herstellung eines Medikaments für die Behandlung von viralen Infektionen
ATE78395T1 (de) Verwendung von dopamin-agonisten zur herstellung eines arzneimittels zur behandlung von psychostimulant-sucht.
DE68905657D1 (de) Verwendung von arginin-aspartat zur herstellung eines arzneimittels zur behandlung gewisser gedaechtnisstoerungen.
DE69300037D1 (de) Verwendung von Bucillamin zur Herstellung eines Arzneimittels zur Behandlung von Cystinuria.
DE69100171D1 (de) Synergistische kombination zur ophthalmischen verwendung.
ATE114464T1 (de) Verwendung von zofenopril zur herstellung von medikamenten gegen rheumatoide arthritis.
DE59202454D1 (de) Verfahren zur Herstellung von TiO2-haltigen Pellets und deren Verwendung.
DE69202842D1 (de) Verbessertes Herzstück und Verfahren zur dessen Herstellung.
DE69009989D1 (de) Verwendung von chlormethiazol zur herstellung eines artzneimittels zur prophylaxe oder therapie der neurodegeneration.
DE69222032D1 (de) Verfahren zur kombinierten herstellung von stickstoff und sauerstoff mit regelbarem durchfluss

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
R071 Expiry of right

Ref document number: 547952

Country of ref document: EP